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Homology and Domain Based Search Tools

This repository provides scripts for homology and domain-based searches in transcriptomes or proteomes

1. BLAST (Basic Local Alignment Search Tool)

  • BLAST is the most commonly used tool and allows you to find similar sequences by aligning your query against local or online databases
  • Local BLAST is highly recommended for fast searches on large datasets, high-throughput analysis and custom database searches

2. Pfam (Protein Family Database)

Pfam provides HMM profiles for protein domains. Using HMMER tools, you can detect conserved domains in your protein sequences

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