Technical framework for Health Information Exchange (HIE) integration - patterns for interoperability, resilience, and HIPAA compliance
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Updated
Jan 31, 2026 - Shell
Technical framework for Health Information Exchange (HIE) integration - patterns for interoperability, resilience, and HIPAA compliance
Communication-first, identity-proofed interoperability for person-centered care.
FHIR-Native Clinical Data Interoperability Framework — Canonical profiles, HL7 v2/C-CDA mapping, computable quality metrics, provenance tracking, and verifiable exchange bundles for digital health data systems.
Kno2 provides Interoperability as a Service for healthcare - a single Communication API to SEND, RECEIVE, and FIND patient information across the healthcare ecosystem. One connection reaches Direct Secure Messaging, clinical document exchange, HL7 FHIR resources, HL7 V2.x, cloud fax, and national record location and retrieval through Kno2's…
Predoc is an AI-native medical records platform that automates the retrieval, aggregation, normalization, de-duplication, and structured delivery of complete patient histories. It queries health information exchanges (HIEs) and initiates outreach to non-connected providers, ingests faxes, PDFs, and digital formats, and delivers clean…
Collective Medical is a full-continuum, real-time care collaboration network for healthcare, connecting hospitals, health systems, post-acute providers, health plans, and payers so care teams can coordinate around complex, high-risk, and vulnerable patients across the entire patient journey.
Collectivemedical — Collective Medical was a Salt Lake City-based healthtech company that operated a real-time care-collaboration network connecting hospitals, emergency departments, health plans, and provider organizations to identify and coordinate care for high-risk and complex patients.
Federated health information exchange reference: EU/US jurisdiction cells, OPA policy-as-code, OPAL live consent, FHIR R4
Smile Digital Health (formerly Smile CDR) is a Toronto-based health interoperability software company and the commercial steward of the open source HAPI FHIR project (the world's most widely deployed Java implementation of the HL7 FHIR standard).
OPAL policy mirror for Cloud Healthcare Exchange — Rego authorization bundle (ADR 0007)
Curve Health is a New York City-based digital health technology company, founded in 2020, that delivers a virtual care and telemedicine platform purpose-built for skilled nursing facilities (SNFs) and senior care.
eClinicalWorks is a cloud-based EHR and practice management platform serving more than 180,000 physicians and 850,000 medical professionals. It provides REST and FHIR-compliant APIs for accessing patient data, appointments, clinical notes, billing, and health information exchange.
Particle Health is a healthcare data interoperability platform that aggregates patient medical records from across the US healthcare system into a single RESTful API. Particle is connected to all three nationwide health information exchange networks (Carequality, CommonWell, eHealth Exchange), TEFCA / QHIN partners, state HIEs (Healthix in New…
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