Multi-scale bioinformatics pipeline for patient-specific drug screening via computational simulation of patient-derived organoids. Integrates U-Net segmentation, agent-based cell simulation, QSAR drug modelling and PDE diffusion.

Official Research Repository for TEMPO: A Novel Hybrid Neuromorphic Framework for Efficient and Interpretable Integration of Multi-Omic High-Dimensional Oncology Data

GNN optimization for Protein Interaction (PPI) analysis in Oncology. Implements normalized graph convolution for stable Edge AI execution on SBC

End-to-end computational platform for pharmaceutical-grade cancer biomarker discovery. Integrates multi-omics data, machine learning, and clinical validation frameworks for precision oncology applications.

Edge-GNN: Constraint-aware graph neural networks for biological interaction modeling under edge deployment constraints (computational oncology, PPI networks).

Fisher-Kolmogorov reaction-diffusion model for simulating glioma invasion: 1D/2D/3D solvers with anisotropic diffusion and therapy simulation

Digital patient generation and drug response prediction via TCGA-DepMap integration — CVAE virtual patients, multi-level similarity scoring, 578-compound drug profiling

LLM-driven multi-agent simulation of the KRAS G12D pancreatic tumor microenvironment — emergent immunosuppression, NK/DC agents, ablation studies. bioRxiv 2026.

Operator-theoretic spatial biology framework for tumor–immune interface analysis using Hodge decomposition, antisymmetric commutator geometry, and graph operator dynamics. Validated across HCC, IMC, CABO/NIVO, and a pan-cancer Visium cohort (26 sections, 118k+ spots, 6 cancer types).

Stability-optimised Program Architecture Reconstruction frameworK: A graph-based algorithmic framework integrating multimodality filtering, network construction, community detection, and stability-based parameter selection within a reproducible workflow

Weighted combination of distance metrics on cancer mutation trees, optimized with survival data for prognostic prediction in AML and Breast Cancer.