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code documentation of study 3, effects of optical defocus on choroidal thickness

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defocus_and_choroidal_thickness

Code documentation of study: effects of optical defocus on choroidal thickness

Purpose: to compile and to analyses topographical choroidal maps

Jupyter notebook, Python: average_rnfl_layers_after_im_registration.jpynb

Aim: find macula centre (low RNFL thickness) for landmark matching of choroidal thickness maps

Jupyter notebook, Python: gif_from_projection_of_anterior_segment.jpynb

Aim: create gif from intra participant z-projection of anterior segment of the eye from OCT scans to estimate quality of transformation, i.e., finding shifts between scans

Jupyter notebook, Python: averaged_choroid_thickess_data_from_reg_scansV2.jpynb

Aim: use transformation info from z-projections to align intra participant choroidal thickness maps

Jupyter notebook, Python: macula_matching_averaging_of_layer_thickness_V3.jpynb

Aim: compile topographical choroidal thickness map

  • Use macula centre position to match inter participant choroidal thickness maps
  • Disregard data from optic nerve head using annotated z-projections
  • Apply outlier filtering
  • Calculating residuals for post and pre intervention

Jupyter notebook, Python: choroidal_thickness_residual_visualisation.jpynb

Aim: visualise data and proceed stats

  • Statistical analyses on interparticipant landmark matched choroid thickness residual data
  • Visualization of the residual of interparticipant landmark matched choroid thickness data post and pre intervention

Dependencies of jpynb:

from oct_helpers_lib import OctDataAccess as get_px_meta

  • Easy access of participant’s meta data e.g., file location from oct_helpers_lib import TopconSegmentationData as TSD
  • Extracting specific data from OCT data extractor output file

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code documentation of study 3, effects of optical defocus on choroidal thickness

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