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New term: conducting airway epithelium #3492

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68 changes: 42 additions & 26 deletions src/ontology/uberon-edit.obo
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Original file line number Diff line number Diff line change
Expand Up @@ -34823,8 +34823,7 @@ xref: MA:0001862
xref: NCIT:C33797
xref: UMLS:C1179002 {source="ncithesaurus:Tracheal_Epithelium"}
xref: VHOG:0001045
is_a: UBERON:0000485 ! simple columnar epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: UBERON:1100003 ! conducting airway epithelium
intersection_of: part_of UBERON:0003126 ! trachea
relationship: contributes_to_morphology_of UBERON:0003126 ! trachea
relationship: develops_from UBERON:0003258 ! endoderm of foregut
Expand Down Expand Up @@ -36854,7 +36853,7 @@ intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0002187 ! terminal bronchiole
relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 ! Aleix Puig-Barbé
relationship: has_part CL:0000158 {source="FMA"} ! club cell
relationship: has_part CL:1000271 ! lung ciliated cell
relationship: has_part CL:1000271 ! lung multiciliated epithelial cell
property_value: taxon_notes "A pseudostratified epithelium, containing basal cells, stem cells of the airway, submucosal glands and cartilage rings, is limited to the trachea and large lobar airways in the mouse (Morrisey and Hogan, 2010). This more complex epithelium extends to terminal bronchioles in the human[DOI:10.1242/dev.115469]" xsd:string

[Term]
Expand Down Expand Up @@ -38967,8 +38966,7 @@ xref: FMA:67782
xref: MA:0001839
xref: NCIT:C32231
xref: UMLS:C0599333 {source="ncithesaurus:Bronchial_Epithelium"}
is_a: UBERON:0000485 ! simple columnar epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: UBERON:1100003 ! conducting airway epithelium
intersection_of: part_of UBERON:0002185 ! bronchus
relationship: contributes_to_morphology_of UBERON:0002185 ! bronchus
relationship: has_part CL:0002209 {source="FMA"} ! intermediate epitheliocyte
Expand Down Expand Up @@ -39642,8 +39640,8 @@ intersection_of: part_of UBERON:0002186 ! bronchiole
relationship: contributes_to_morphology_of UBERON:0002186 ! bronchiole
relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 ! Aleix Puig-Barbé
relationship: has_part CL:0000158 ! club cell
relationship: has_part CL:0002145 {source="FMA"} ! ciliated columnar cell of tracheobronchial tree
relationship: has_part CL:1000271 ! lung ciliated cell
relationship: has_part CL:0002145 {source="FMA"} ! multiciliated columnar cell of tracheobronchial tree
relationship: has_part CL:1000271 ! lung multiciliated epithelial cell
relationship: part_of UBERON:0005039 ! mucosa of bronchiole

[Term]
Expand Down Expand Up @@ -47862,11 +47860,11 @@ synonym: "secondary bronchus epithelium" EXACT [OBOL:automatic]
xref: EMAPA:32695
xref: FMA:86624
xref: MA:0001842
intersection_of: UBERON:0000483 ! epithelium
intersection_of: UBERON:1100003 ! conducting airway epithelium
intersection_of: part_of UBERON:0002183 ! lobar bronchus
relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 ! Aleix Puig-Barbé
relationship: has_part CL:0002329 ! basal epithelial cell of tracheobronchial tree
relationship: has_part CL:0002332 ! ciliated cell of the bronchus
relationship: has_part CL:0002332 ! multiciliated epithelial cell of the bronchus
relationship: has_part CL:0017000 ! pulmonary ionocyte

[Term]
Expand Down Expand Up @@ -47897,7 +47895,7 @@ xref: FMA:86625
xref: MA:0001847
xref: VHOG:0001034
is_a: UBERON:0002031 ! epithelium of bronchus
intersection_of: UBERON:0000483 ! epithelium
intersection_of: UBERON:1100003 ! conducting airway epithelium
intersection_of: part_of UBERON:0002182 ! main bronchus
relationship: part_of UBERON:0002182 ! main bronchus

Expand All @@ -47917,16 +47915,16 @@ xref: EMAPA:37740 {source="MA:th"}
xref: FMA:86626
xref: MA:0001850
is_a: UBERON:0002031 ! epithelium of bronchus
intersection_of: UBERON:0000483 ! epithelium
intersection_of: UBERON:1100003 ! conducting airway epithelium
intersection_of: part_of UBERON:0002184 ! segmental bronchus
relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 ! Aleix Puig-Barbé
relationship: has_part CL:0000158 ! club cell
relationship: has_part CL:0002208 ! brush cell of bronchus
relationship: has_part CL:0002329 ! basal epithelial cell of tracheobronchial tree
relationship: has_part CL:0002332 ! ciliated cell of the bronchus
relationship: has_part CL:0002332 ! multiciliated epithelial cell of the bronchus
relationship: has_part CL:0017000 ! pulmonary ionocyte
relationship: has_part CL:1000143 ! lung goblet cell
relationship: has_part CL:1000223 ! lung neuroendocrine cell
relationship: has_part CL:1000223 ! pulmonary neuroendocrine cell
relationship: part_of UBERON:0002184 ! segmental bronchus

[Term]
Expand Down Expand Up @@ -72967,8 +72965,8 @@ id: UBERON:0003532
name: hindlimb skin
def: "A zone of skin that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic]
synonym: "hind limb skin" EXACT [OBOL:automatic]
synonym: "lower limb skin" EXACT [FMA:23102]
synonym: "lower limb skin" EXACT [https://orcid.org/0000-0002-0819-0473]
synonym: "lower limb skin" EXACT [FMA:23102]
synonym: "skin of hind limb" EXACT [OBOL:automatic]
synonym: "skin of hindlimb" EXACT [OBOL:automatic]
synonym: "skin of lower extremity" EXACT [OBOL:automatic]
Expand Down Expand Up @@ -92458,19 +92456,15 @@ property_value: structure_notes "The epithelium of the cervix is varied. The ect
[Term]
id: UBERON:0004802
name: respiratory tract epithelium
def: "The pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi." [ISBN:0-683-40008-8, MGI:anna, MP:0010942]
subset: pheno_slim
def: "An epithelium that is part of the respiratory tract." [ISBN:0-683-40008-8]
synonym: "airway epithelium" RELATED [BTO:0000419]
synonym: "epithelial tissue of respiratory tract" EXACT [OBOL:automatic]
synonym: "epithelium of respiratory tract" EXACT [OBOL:automatic]
synonym: "respiratory epithelium" RELATED [BTO:0000419]
synonym: "respiratory tract epithelial tissue" EXACT [OBOL:automatic]
xref: BTO:0000419
xref: CALOHA:TS-0023
xref: EMAPA:32827
xref: MA:0001480
xref: SCTID:321764001
is_a: UBERON:0010499 ! pseudostratified ciliated columnar epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000065 ! respiratory tract
relationship: contributes_to_morphology_of UBERON:0001004 ! respiratory system
Expand Down Expand Up @@ -116141,7 +116135,7 @@ xref: NCIT:C45715
xref: UMLS:C0682578 {source="ncithesaurus:Glandular_Epithelium"}
xref: UMLS:C1708242 {source="ncithesaurus:Glandular_Epithelial_Tissue"}
intersection_of: UBERON:0000483 ! epithelium
intersection_of: composed_primarily_of CL:0000150 ! glandular epithelial cell
intersection_of: composed_primarily_of CL:0000150 ! glandular secretory epithelial cell
disjoint_from: UBERON:0011952 ! non-glandular epithelium
property_value: editor_note "consider splitting epithelium from epithelial tissue" xsd:string

Expand Down Expand Up @@ -117484,14 +117478,14 @@ xref: FMA:64800
xref: NCIT:C13182
xref: UMLS:C0225337 {source="ncithesaurus:Columnar_Epithelium"}
intersection_of: UBERON:0000485 ! simple columnar epithelium
intersection_of: composed_primarily_of CL:0000150 ! glandular epithelial cell
intersection_of: composed_primarily_of CL:0000150 ! glandular secretory epithelial cell

[Term]
id: UBERON:0006930
name: glandular cuboidal epithelium
xref: FMA:66809
intersection_of: UBERON:0000484 ! simple cuboidal epithelium
intersection_of: composed_primarily_of CL:0000150 ! glandular epithelial cell
intersection_of: composed_primarily_of CL:0000150 ! glandular secretory epithelial cell

[Term]
id: UBERON:0006931
Expand Down Expand Up @@ -134919,7 +134913,7 @@ synonym: "pulmonary neuroepithelial body" EXACT [MP:0010921]
xref: EMAPA:37943 {source="MA:th"}
is_a: UBERON:0000061 {source="MP"} ! anatomical structure
relationship: contributes_to_morphology_of UBERON:0000115 ! lung epithelium
relationship: has_part CL:1000223 ! lung neuroendocrine cell
relationship: has_part CL:1000223 ! pulmonary neuroendocrine cell
relationship: part_of UBERON:0000115 ! lung epithelium
relationship: part_of UBERON:8600018 ! neuroendocrine system

Expand Down Expand Up @@ -166343,7 +166337,7 @@ name: left lung lobar bronchus epithelium
def: "An epithelium that is part of a lobar bronchus of left lung." [OBOL:automatic]
xref: EMAPA:17658
xref: MA:0003135
intersection_of: UBERON:0000483 ! epithelium
intersection_of: UBERON:1100003 ! conducting airway epithelium
intersection_of: part_of UBERON:0003405 ! lobar bronchus of left lung

[Term]
Expand All @@ -166352,7 +166346,7 @@ name: right lung lobar bronchus epitheium
def: "An epithelium that is part of a lobar bronchus of right lung." [OBOL:automatic]
xref: EMAPA:17666
xref: MA:0003136
intersection_of: UBERON:0000483 ! epithelium
intersection_of: UBERON:1100003 ! conducting airway epithelium
intersection_of: part_of UBERON:0003404 ! lobar bronchus of right lung

[Term]
Expand Down Expand Up @@ -189986,6 +189980,28 @@ intersection_of: connects UBERON:0004921 ! subdivision of digestive tract
relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 ! David Osumi-Sutherland
creation_date: 2021-02-05T11:19:31Z

[Term]
id: UBERON:1100003
name: conducting airway epithelium
def: "The pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi." [ISBN:0-683-40008-8, MGI:anna, MP:0010942]
synonym: "airway epithelium" RELATED [BTO:0000419]
xref: CALOHA:TS-0023
xref: EMAPA:32827
xref: MA:0001480
xref: SCTID:321764001
intersection_of: UBERON:0010499 ! pseudostratified ciliated columnar epithelium
intersection_of: part_of UBERON:0000065 ! respiratory tract
relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 ! David Osumi-Sutherland
property_value: dcterms-date "2025-03-17T12:43:44Z" xsd:dateTime

[Term]
id: UBERON:1100004
name: pseudostratified ciliated epithelium of larynx
intersection_of: UBERON:0010499 ! pseudostratified ciliated columnar epithelium
intersection_of: part_of UBERON:0001737 ! larynx
relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 ! David Osumi-Sutherland
property_value: dcterms-date "2025-03-17T12:59:29Z" xsd:dateTime

[Term]
id: UBERON:1500000
name: scapular blade
Expand Down Expand Up @@ -223958,7 +223974,7 @@ name: epithelium of lobular bronchiole
def: "An epithelium of the lobular bronchiole." [FMA:62497]
synonym: "epithelium of preterminal bronchiole" EXACT [PMID:16543587]
synonym: "lobular bronchiole epithelium" EXACT [FMA:62497]
intersection_of: UBERON:0000483 ! epithelium
intersection_of: UBERON:1100003 ! conducting airway epithelium
intersection_of: part_of UBERON:8600000 ! lobular bronchiole
relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 ! Aleix Puig-Barbé
property_value: dcterms-date "2023-02-10T14:26:09Z" xsd:dateTime
Expand Down