Skip to content

Conversation

@JABelfiore
Copy link
Collaborator

No description provided.

enterocyte of epithelium of small intestine --> small intestine enterocyte
early enterocyte --> early small intestine enterocyte.
@JABelfiore JABelfiore requested a review from dosumis February 10, 2025 16:47
@JABelfiore JABelfiore self-assigned this Feb 10, 2025
@JABelfiore JABelfiore linked an issue Feb 10, 2025 that may be closed by this pull request
@JABelfiore JABelfiore changed the title 2882 enterocyte refactor renaming Enterocyte refactor renaming Feb 10, 2025
@dosumis
Copy link
Contributor

dosumis commented Feb 14, 2025

#gogoeditdiff

@github-actions
Copy link
Contributor

github-actions bot commented Feb 14, 2025

Here's a diff of how these changes impact the classified ontology (on -base file):

Ontology comparison

Left

  • Ontology IRI: http://purl.obolibrary.org/obo/cl/cl-base.owl
  • Version IRI: http://purl.obolibrary.org/obo/cl/releases/2025-03-12/cl-base.owl
  • Loaded from: file:/__w/cell-ontology/cell-ontology/src/ontology/cl-base-master.owl/cl-base.owl

Right

  • Ontology IRI: http://purl.obolibrary.org/obo/cl/cl-base.owl
  • Version IRI: http://purl.obolibrary.org/obo/cl/releases/2025-03-12/cl-base.owl
  • Loaded from: file:/__w/cell-ontology/cell-ontology/src/ontology/cl-base-pr.owl/cl-base.owl

Ontology imports

Ontology annotations

enterocyte http://purl.obolibrary.org/obo/CL_0000584

Removed

Added

  • enterocyte IAO_0000115 "An epithelial cell that has its apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen. This covers both the large and small intestine."

enterocyte of epithelium of intestinal villus http://purl.obolibrary.org/obo/CL_1000335

Added

immature colonocyte http://purl.obolibrary.org/obo/CL_4047018

Removed

Added

immature small intestine enterocyte http://purl.obolibrary.org/obo/CL_4047019

Removed

Added

immature small intestine entrocyte http://purl.obolibrary.org/obo/CL_0008050

Added

mature colonocyte http://purl.obolibrary.org/obo/CL_0008052

Added

mature small intestince enterocyte http://purl.obolibrary.org/obo/CL_0008051

Added

small intestine enterocyte http://purl.obolibrary.org/obo/CL_1000334

Removed

Added

@github-actions
Copy link
Contributor

github-actions bot commented Feb 14, 2025

Here's a diff of your edit file (unreasoned)

Ontology comparison

Left

  • Ontology IRI: http://purl.obolibrary.org/obo/cl-edit.owl
  • Version IRI: None
  • Loaded from: file:/__w/cell-ontology/cell-ontology/master/src/ontology/cl-edit.owl

Right

  • Ontology IRI: http://purl.obolibrary.org/obo/cl-edit.owl
  • Version IRI: None
  • Loaded from: file:/__w/cell-ontology/cell-ontology/branch/src/ontology/cl-edit.owl

Ontology imports

Ontology annotations

early colonocyte http://purl.obolibrary.org/obo/CL_4047018

Removed

Added

early enterocyte http://purl.obolibrary.org/obo/CL_4047019

Removed

Added

enterocyte http://purl.obolibrary.org/obo/CL_0000584

Removed

Added

  • enterocyte definition "An epithelial cell that has its apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen. This covers both the large and small intestine."

enterocyte of epithelium of intestinal villus http://purl.obolibrary.org/obo/CL_1000335

Added

enterocyte of epithelium of small intestine http://purl.obolibrary.org/obo/CL_1000334

Removed

Added

immature small intestine entrocyte http://purl.obolibrary.org/obo/CL_0008050

Added

mature colonocyte http://purl.obolibrary.org/obo/CL_0008052

Added

mature small intestince enterocyte http://purl.obolibrary.org/obo/CL_0008051

Added

JABelfiore and others added 8 commits February 18, 2025 10:52
- [x] Make sure early is not part of standard/mature
- [x] Get rid of differentiated enterocyte from synonyms
- [x] Mature and immature to be used instead of early and late
QUick attempt at fix.  Needs review to see if any more earlier changes need reverting.
@dosumis
Copy link
Contributor

dosumis commented Mar 12, 2025

#gogoeditdiff

@github-actions
Copy link
Contributor

Your branch is 3 commit/s behind, please update your branch.

@dosumis
Copy link
Contributor

dosumis commented Mar 12, 2025

#gogoeditdiff

@dosumis dosumis marked this pull request as draft March 12, 2025 12:21
@dosumis
Copy link
Contributor

dosumis commented Apr 2, 2025

Remaining issues:

  1. General definition of enterocyte refers to mature state. Ditto colonocyte.
  2. Defs needed for mature colonocyte + immature and mature small intestine enterocyte
  3. EC def of immature small intestine enterocyte is dubious
  4. Species neutral terminology: Can we make enterocyte neutral, or should we aim to use 'gut absorptive cell'? A: making either species neutral requires deleting taxon restriction on mucosa to chordata (in Uberon). Suggest push to second ticket.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment

Labels

None yet

Projects

None yet

Development

Successfully merging this pull request may close these issues.

Enterocyte refactor & renaming

3 participants