31: Sample data: social interaction EEG data
Attention-deficit hyperactivity disorder (ADHD) is characterized by symptoms of inattention and/or hyperactivity-impulsivity. This neurodevelopmental disorder becomes apparent before the age of twelve (American Psychiatric Association, 2013). The prevalence of ADHD in primary school children is 11.4% (Willcutt, 2012). Currently, the diagnosis and classification of ADHD primarily depend on the clinical observation of patients’ behavior and on diagnostic interviews (American Psychiatric Association, 2013).
Here, we used complex naturalistic stimuli to probe the neural correlates of social perception in ADHD. Specifically, two versions of tailored movie films with the same scenes and crews but different with high- or low-level of social interactions were shown to participants. Their EEG signals were continuously recorded during movie viewing. The goal is to classify the individual contributing to the EEG data belongs to either the healthy control or ADHD group.
Twenty-eight children with ADHD and 20 age-matched controls were enrolled in this study. Their ages ranged between 6 and 15 years. All participants with ADHD were recruited from the outpatient clinics at a tertiary medical center in northern Taiwan. They met the DSM-5 criteria for the diagnosis of ADHD (American Psychiatric Association, 2013), and none had taken any ADHD drug before participating in the experiment (i.e. they were ADHD medication-naïve). The control children were age-matched to the ADHD group and were recruited from ordinary primary schools and outpatient clinics.
EEG was collected from each participant to exclude epilepsy. All children had normal or corrected-to-normal vision. No participant had any psychiatric or neurological disorders, and none was taking any medication. Children with autism spectrum disorder were excluded from our study.
The study was approved by the Research Ethics Review Committee of Far Eastern Memorial Hospital, New Taipei City, Taiwan. Informed consent forms were obtained from all participants and their parents.
Two movie clips were professionally filmed with the same crew (four players) to have either a high- or low-level of verbal and non-verbal social interactions. The theme of the movie was people playing basketball at an outdoor court. Scenes in two movie clips were matched between each other. The duration of each movie was 5’05”. Participants were instructed to view movies. Each movie will be shown once to each participant. The order of first showing the low- or a high-level social interaction movie was randomized across participants. The figure below shows six representative snapshots of two movies.
EEG data (NicoletOne, Natus, Pleasanton, CA, USA) were sampled at 256 Hz at 21 channels. The topology of EEG electrodes followed the international 10-20 system. EEG was recorded continuously for each participant for the whole duration of the movie clip using a 20-channel cap.
EEG data from 28 ADHD patients and 28 healthy controls can be downloaded at University of Toronto OneDrive. Data are Matlab mat files. Variables data_high and data_low are EEG data during viewing high- and low-level social interaction movies, respectively.