v1.59.1 - RYR1 fix

1.59.1 (2026-06-18)

• fix: data fix for RYR1 (35a0eac)

Full DB export available: https://files.cpicpgx.org/data/database/cpic_db_dump-v1.59.1.sql.gz

v1.59.0 - Ondansetron guideline + RYR1 + PharmVar update

1.59.0 (2026-06-17)

• fix: add db role grant to bootstrap script (55654dd)
• fix: fix bug when loading phenotype history (68f83bb)
• fix: fix the FrequencyCalculator to use the new Frequency data structure and not aggregate allelels (cb0d892)
• fix: stop polling PharmVar IDs on every deployment (72e2d4a)
• feat: add docs for coding agents (7d88a8b)
• feat: add task for dumping changelog (bab9763)
• feat: data update (e4b6c9c)
• feat: new CYP2D6 allele (5376d83)
• feat: new CYP3A5 and NUDT15 alleles (1751dc1)
• feat: ondansetron guideline update (f7ea077)

Full DB export available: https://files.cpicpgx.org/data/database/cpic_db_dump-v1.59.0.sql.gz

v1.58.0

1.58.0 (2026-05-14)

• feat: support "Retired" pairs and update peginterferon guideline data (079f962)
• data: retired pairs for peginterferon guideline

Full DB export available: https://files.cpicpgx.org/data/database/cpic_db_dump-v1.58.0.sql.gz

v1.57.0

1.57.0 (2026-05-12)

• feat: add change log import for phenotype files (c45a659)
• feat: add thiopurines correction PDF as supplement to publication (0b72e64)
• feat: data update (2a1c6ba)
• fix: fix bug in gene resource importer to handle PharmGKB ID correctly (335e6c5)

Full DB export available: https://files.cpicpgx.org/data/database/cpic_db_dump-v1.57.0.sql.gz

v1.56.0

1.56.0 (2026-05-01)

• feat: data update (8c93ddd)
• fix: fix PharmVar API usage (c82da7c)

Full DB export available: https://files.cpicpgx.org/data/database/cpic_db_dump-v1.56.0.sql.gz

v1.55.0 - Move to ClinPGx

1.55.0 (2026-03-13)

THIS RELEASE MAY BREAK YOUR CODE

As seen in the changelog below, names of columns have been changed to accommodate the move from PharmGKB to ClinPGx. The semantic meaning is the same but the names have changed. Please see the ClinPGx blog for more details.

• fix: change guideline links to clinpgx.org (cb71681)
• fix: more URL changes to clinpgx.org (5ee5faf)
• fix: remove NUDT15*2 from allele definitions file (866edda)
• fix: rename pgkbcalevel to clinpgxlevel (f957c58)
• fix: update thiopurine recommendation files (c26148d)
• chore: remove data source config (8b3e81c)
• feat: convert PharmGKB references to ClinPGx (333ef5d)
• feat: CYP2C19 allele definition update from PharmVar (73637d1)

Full DB export available: https://files.cpicpgx.org/data/database/cpic_db_dump-v1.55.0.sql.gz

v1.54.0 - Thiopurines guideline update

1.54.0 (2026-02-04)

• fix: change command for exporting data change log (0d0ba19)
• feat: data update (48c94f7)

Full DB export available: https://files.cpicpgx.org/data/database/cpic_db_dump-v1.54.0.sql.gz

v1.53.2 - NAT2 Alleles Fix

1.53.2 (2025-10-28)

• fix: updated to the correct NAT2 allele definition list (b62dd20)

Full DB export available: https://files.cpicpgx.org/data/database/cpic_db_dump-v1.53.2.sql.gz

v1.53.1

1.53.1 (2025-10-27)

• fix: corrected c.930 allele in MT-RNR1 from A>G to G>A (583fd18)

Full DB export available: https://files.cpicpgx.org/data/database/cpic_db_dump-v1.53.1.sql.gz

v1.53.0

1.53.0 (2025-10-20)

• chore: update dependencies (c34e679)
• feat: data update from PharmVar 6.2.17 (a2f3d34)

Full DB export available: https://files.cpicpgx.org/data/database/cpic_db_dump-v1.53.0.sql.gz