Releases: adoebley/Griffin
Releases · adoebley/Griffin
v0.2.0 revisions version
This includes a number of updates made while revising the manuscript:
- Sites no longer need to be filtered for mappability before running Griffin (Instead, Griffin excludes positions with known problems using the encode unified exclusion list, centromere positions, sequence patches and other lists)
- Minor corrections have been made to the GC correction procedure
- A mappability correction option has been added (not recommended and currently not in the snakemake)
- GC correction and nucleosome profiling run faster
- New output structure (hopefully easier to use)
- CNA normalization option which corrects each site by the local coverage (not recommended except when looking at individual sites, can be turned on by setting
CNA_normalization: True
and providing a large normalization window to capture the surrounding coveragenorm_window: -50000 50000
)