Issues

• Curate r_1603: the thiamine pyrimidine (HMP-P) synthase uses PLP and histidine and needs O2

  curation
  SysBioChalmers/yeast-GEM#424 · Filter by author edkerk opened on Oct 7, 2026

• Reconsider small and inconsistently named subsystems

  curation
  SysBioChalmers/yeast-GEM#420 · Filter by author edkerk opened on Oct 7, 2026

• Ferrocytochrome b5 in the ER (s_4209) has charge 3 and ferricytochrome cross-references

  curation
  SysBioChalmers/yeast-GEM#419 · Filter by author edkerk opened on Oct 5, 2026

• Proton leak (r_2129) is unbounded and can absorb oxygen without ATP

  SysBioChalmers/yeast-GEM#418 · Filter by author edkerk opened on Sep 25, 2026

• ecYeastGEM: enzyme-constrained model available via ecModels; automated reconstruction planned

  SysBioChalmers/yeast-GEM#416 · Filter by author edkerk opened on Sep 24, 2026

• Curation backlog: non-blocking findings from model-qc.yml

  SysBioChalmers/yeast-GEM#408 · Filter by author edkerk opened on Sep 1, 2026

• Implement YAML-based curation

  SysBioChalmers/yeast-GEM#379 · Filter by author edkerk opened on Dec 22, 2024
  2

  

• Yeast-GEM visualization?

  SysBioChalmers/yeast-GEM#367 · Filter by author forxhunter opened on Jul 29, 2024
  4

• feat: function to report if flux vector is ΔG-compatible

  enhancement
  SysBioChalmers/yeast-GEM#353 · Filter by author edkerk opened on Sep 28, 2023

• duplicate metabolites identified

  SysBioChalmers/yeast-GEM#338 · Filter by author feiranl opened on Jun 6, 2023
  1

• reaction references

  SysBioChalmers/yeast-GEM#334 · Filter by author mihai-sysbio opened on Apr 11, 2023

• feat: single ec-code annotation per reaction

  SysBioChalmers/yeast-GEM#319 · Filter by author edkerk opened on Jun 5, 2022
  5

  

• feat: KEGG pathway annotation

  SysBioChalmers/yeast-GEM#317 · Filter by author edkerk opened on Jun 5, 2022

• Feat-stoichiometry coefficients for subunits in the enzyme complex

  SysBioChalmers/yeast-GEM#297 · Filter by author feiranl opened on Jan 31, 2022
  10

• Fix-amino acid pathways localization

  bugwip
  SysBioChalmers/yeast-GEM#294 · Filter by author feiranl opened on Jan 31, 2022
  1

  

• feat: have SLIMEr as option

  SysBioChalmers/yeast-GEM#289 · Filter by author edkerk opened on Dec 11, 2021

• feat: curate grRules with GPRuler output

  SysBioChalmers/yeast-GEM#288 · Filter by author edkerk opened on Dec 11, 2021
  

• doc: tutorial for yeast-GEM

  SysBioChalmers/yeast-GEM#286 · Filter by author edkerk opened on Dec 10, 2021

• feat:Missing annotations for Rhea and ModelSEED database

  help wanted
  SysBioChalmers/yeast-GEM#231 · Filter by author feiranl opened on Jun 19, 2020
  3

• fix: remove generic reactions

  question
  SysBioChalmers/yeast-GEM#219 · Filter by author BenjaSanchez opened on May 5, 2020
  5

• feat: allow contributions from python users

  format fixstandby
  SysBioChalmers/yeast-GEM#218 · Filter by author BenjaSanchez opened on Apr 24, 2020
  1

• fix: mass- and charge balance reactions

  bughelp wanted
  SysBioChalmers/yeast-GEM#194 · Filter by author edkerk opened on Jul 22, 2019
  2

  

• fix: biomass tests from memote

  memotestandby
  SysBioChalmers/yeast-GEM#138 · Filter by author BenjaSanchez opened on Jul 13, 2018
  1

• fix: stoichiometric consistency due to SLIME rxns

  help wantedmemotequestion
  SysBioChalmers/yeast-GEM#135 · Filter by author BenjaSanchez opened on Jul 13, 2018

• ATP/NADH issue

  question
  SysBioChalmers/yeast-GEM#64 · Filter by author feiranl opened on Feb 12, 2018
  6