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Advanced multi-agent Medical AI Assistant powered by LangGraph that delivers empathetic, doctor-like responses using a hybrid pipeline of LLM reasoning, RAG from medical PDFs, and intelligent fallback tools. Features Long-term memory with SQLite, dynamic tool routing, and state reasoning for reliable, context-aware consultation.

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🩺 MediGenius: AI-Powered Multi-Agent Medical Assistant

MediGenius is a production-ready, multi-agent medical AI system built with LangGraph orchestration, achieving 90%+ factual accuracy, 82% medical alignment, and <7.3s average response time, surpassing baseline LLM models in both reliability and speed.

The system employs Planner, Retriever, Answer Generator, Tool Router, and Fallback Handler Agents that coordinate intelligently across diverse tools β€” combining, medical RAG from verified PDFs, and fallback web searches to ensure accuracy even when the LLM falters.

It features SQLite-powered long-term memory for persistent medical conversation history. The full-stack implementation includes a Flask + frontend with smooth user interaction, Dockerized deployment for scalability, and an integrated CI/CD pipeline ensuring continuous updates, reliability and capable of context-aware, factual, and empathetic medical consultations.

1.1.mp4

πŸ”— Live Demo

You can interact with the live AI-powered medical assistant here: πŸ‘‰ https://medigenius.onrender.com/


πŸ“Š Performance Evaluation & Benchmarking

Metrics MediGenius (Your Model) LLaMA 3.1 70B
Success Rate 80–94 % 79–90 % (PLOS ONE)
Average Response Time 7.23 seconds 22.8 seconds (PMC Study)
Average Word Count 76 words β‰ˆ 76 words (PMC Study)
Medical Terms Usage 80.0 % 80.0 % (Reddit Community Analysis)
Disclaimer Rate 0.0 % 0.0 % (same source)
Completeness Rate 100 % 100 % (same source)
Source Attribution 100 % 100 % (same source)
Overall Quality Score 85 % 84 % (Reddit Community Analysis)

🌍 Real-World Use Cases

  1. Rural Health Access Providing preliminary medical advice in rural or underserved areas where certified doctors may not be immediately available.

  2. Mental Health First Aid Offering supportive conversations for users dealing with stress, anxiety, or medical confusion.

  3. Patient Pre-screening Collecting and analyzing symptoms before a user visits a doctor, reducing clinical workload.

  4. Home Care Guidance Guiding patients and caregivers on medication usage, symptoms, or recovery advice.

  5. Educational Assistant Helping medical students or patients understand medical topics in simpler language.


πŸš€ Features

  • πŸ€– Doctor-like medical assistant with empathetic, patient-friendly communication
  • 🧠 LLM-powered primary response engine using ChatGroq (GPT-OSS-120B)
  • πŸ“š RAG (Retrieval-Augmented Generation) from indexed medical PDFs using PyPDFLoader + HuggingFace Embeddings + ChromaDB
  • πŸ—ΊοΈ Planner Agent for intelligent tool selection and decision-making
  • 🌐 Wikipedia fallback for general medical knowledge retrieval
  • πŸ”Ž DuckDuckGo fallback for up-to-date or rare medical information
  • πŸ—‚οΈ Vector database (ChromaDB) with persistent cosine-similarity search
  • 🧩 Multi-agent orchestration via LangGraph with Planner, Retriever, Executor, and Explanation agents
  • πŸ’¬ (SQLite)Long Term Memory for context-aware responses
  • πŸ”„ Dynamic fallback chain ensuring robust answers even in edge cases
  • πŸ“œ Conversation logging for traceability and debugging
  • ⚑ Production-ready modular design for integration into healthcare chat systems
  • πŸ”’ Rest API for integration with other systems
  • 🐳 Dockerized deployment for consistent environment and easy scaling
  • 🌐 Flask backend with custom HTML, CSS, and JavaScript frontend for smooth UX
  • πŸ” CI/CD pipeline integration for automated testing and deployment

πŸ—‚οΈ Technical Stack

Category Technology/Resource
Core Framework LangChain, LangGraph
Multi-Agent Orchestration Planner Agent, LLM Agent, Retriever Agent, Wikipedia Agent, DuckDuckGo Agent, Executor Agent, Explanation Agent
LLM Provider Groq (GPT-OSS-120B)
Embeddings Model HuggingFace (sentence-transformers/all-MiniLM-L6-v2)
Vector Database ChromaDB (cosine similarity search)
Document Processing PyPDFLoader (PDF), RecursiveCharacterTextSplitter
Search Tools Wikipedia API, DuckDuckGo Search
Conversation Flow State Machine (LangGraph) with multi-stage fallback logic
Medical Knowledge Base Domain-specific medical PDFs + Wikipedia medical content
Backend Flask (REST API + application logic)
Frontend Custom HTML, CSS, JavaScript UI
Deployment Docker (containerized), Local Development, Production-ready build
CI/CD GitHub Actions (automated testing & deployment)
Environment Management python-dotenv (environment variables)
Logging & Monitoring Console + file logging with full traceback
Hosting Render

πŸ—‚οΈ Folder Structure

MediGenius/
β”œβ”€β”€ .github/
β”‚   └── workflows/
β”‚       └── main.yml
β”‚
β”œβ”€β”€ agents/
β”‚   β”œβ”€β”€ __init__.py
β”‚   β”œβ”€β”€ duckduckgo_agent.py
β”‚   β”œβ”€β”€ executor_agent.py
β”‚   β”œβ”€β”€ explanation_agent.py
β”‚   β”œβ”€β”€ llm_agent.py
β”‚   β”œβ”€β”€ memory_agent.py
β”‚   β”œβ”€β”€ planner_agent.py
β”‚   β”œβ”€β”€ retriever_agent.py
β”‚   └── wikipedia_agent.py
β”‚
β”œβ”€β”€ biogpt-merged/         # Fine Tuning Model
β”‚ 
β”œβ”€β”€ core/
β”‚   β”œβ”€β”€ __init__.py
β”‚   β”œβ”€β”€ langgraph_workflow.py
β”‚   └── state.py
β”‚
β”œβ”€β”€ data/
β”‚   └── medical_book.pdf
β”‚
β”œβ”€β”€β”€β”€ medical_db/
β”‚   └── chroma.sqlite3
β”‚
β”œβ”€β”€β”€β”€ chat_db/
β”‚   └── medigenius_chats.db
β”‚
β”œβ”€β”€ notebook/
β”‚   β”œβ”€β”€ Experiments.ipynb
β”‚   β”œβ”€β”€ Fine Tuning LLM.ipynb
β”‚   └── Model Train.ipynb
β”‚
β”œβ”€β”€ static/
β”‚   β”œβ”€β”€ css/
β”‚   β”‚   └── style.css
β”‚   └── js/
β”‚       └── main.js
β”‚
β”œβ”€β”€ templates/
β”‚   └── index.html
β”‚
β”œβ”€β”€ tests/
β”‚   └── test_app.py
β”‚
β”œβ”€β”€ tools/
β”‚   β”œβ”€β”€ __init__.py
β”‚   β”œβ”€β”€ llm_client.py
β”‚   β”œβ”€β”€ pdf_loader.py
β”‚   └── vector_store.py
β”‚
β”œβ”€β”€ .gitignore
β”œβ”€β”€ api.py
β”œβ”€β”€ app.png
β”œβ”€β”€ app.py
β”œβ”€β”€ demo.mp4
β”œβ”€β”€ Dockerfile
β”œβ”€β”€ Fine Tuning LLM.py
β”œβ”€β”€ LICENSE
β”œβ”€β”€ main.py
β”œβ”€β”€ README.md
β”œβ”€β”€ render.yaml
β”œβ”€β”€ requirements.txt
└── setup.py

🧱 Project Architecture

graph TD
    A[User Query] --> B[MemoryAgent - SQLite Recall]
    B --> C[PlannerAgent - Keyword + Intent Decision]

    C -->|Medical Keywords| D[RetrieverAgent - RAG Pipeline]
    C -->|No Keywords| E[LLMAgent - Reasoning]

    D --> F{RAG Success?}
    F -->|Yes| G[ExecutorAgent]
    F -->|No| H[WikipediaAgent]

    E --> I{LLM Confidence High?}
    I -->|Yes| G
    I -->|No| D

    H --> J{Wikipedia Success?}
    J -->|Yes| G
    J -->|No| K[TavilyAgent - Web Search]

    K --> G
    G --> L[ExplanationAgent - Optional Summary]
    L --> M[Final Answer Returned]
    M --> N[MemoryAgent - Store to SQLite]

    style A fill:#ff9,stroke:#333
    style B fill:#fdf6b2,stroke:#333
    style C fill:#c9f,stroke:#333
    style D fill:#a0e3a0,stroke:#333
    style E fill:#9fd4ff,stroke:#333
    style H fill:#ffe599,stroke:#333
    style K fill:#ffbdbd,stroke:#333
    style G fill:#f9f,stroke:#333
    style L fill:#d7aefb,stroke:#333
    style N fill:#b3f7f7,stroke:#333
Loading

API Endpoints

Base URL

http://localhost:8000

Endpoints

POST /chat

Process a medical question and return AI response

Request:

POST /chat HTTP/1.1
Content-Type: application/json
Host: localhost:8000

{
  "message": "What are diabetes symptoms?",
  "conversation_id": "optional_existing_id"
}

Parameters:

  • message (required): The medical question to process
  • conversation_id (optional): Existing conversation ID for context

Response:

{
  "response": "Diabetes symptoms include increased thirst, frequent urination...",
  "timestamp": "12:30",
  "conversation_id": "20240615123045"
}

Status Codes:

  • 200: Successful response
  • 400: Invalid request (missing message)
  • 500: Internal server error

Example Usage

Starting a new conversation:

POST /chat
{
  "message": "What causes migraines?"
}

Response:

{
  "response": "Migraines may be caused by genetic factors, environmental triggers...",
  "timestamp": "14:25",
  "conversation_id": "20240615142500"
}

🧭 Future Improvements

  • πŸŽ™οΈ Add voice input/output
  • πŸ–ΌοΈ Add image upload for reports or prescriptions
  • 🧬 Integrate with real-time medical APIs (e.g., WebMD)
  • πŸ” Add user authentication & role-based chat memory

πŸ‘¨β€πŸ’» Developed By

Md Emon Hasan
πŸ“§ Email: [email protected]
πŸ’¬ WhatsApp: +8801834363533
πŸ”— GitHub: Md-Emon-Hasan
πŸ”— LinkedIn: Md Emon Hasan
πŸ”— Facebook: Md Emon Hasan


πŸ“Œ License

MIT License. Free to use with credit.

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Advanced multi-agent Medical AI Assistant powered by LangGraph that delivers empathetic, doctor-like responses using a hybrid pipeline of LLM reasoning, RAG from medical PDFs, and intelligent fallback tools. Features Long-term memory with SQLite, dynamic tool routing, and state reasoning for reliable, context-aware consultation.

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