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AliA-Mohamed/README.md

# Hi, I'm Ali Mohamed

PhD candidate in Pharmacological and Biomolecular Sciences at the University of Milan.
I work on motor neuron disorders, focusing on mitochondrial dysfunction in SBMA using iPSC-based models and omics approaches.
My background combines wet-lab experience (cell culture, imaging, molecular biology) with bioinformatics and data analysis (RNA-seq, scRNA-seq, proteomics).


About Me

  • Training in pharmacology, biotechnology, and bioinformatics
  • Research on neurodegeneration: SBMA, Parkinson’s disease, and microglia biology
  • Skilled in omics data analysis and workflow development
  • Interested in bridging lab biology with computational pipelines

Skills

  • Programming & Data Analysis: R, Python, Bash
  • Pipelines & Reproducibility: Snakemake, Nextflow, Conda
  • Omics: RNA-seq, scRNA-seq, proteomics, transcriptomics
  • Experimental: Stem cell culture, mitochondrial function assays, imaging

Selected Projects

  • RNA-seq pipeline: from QC to differential expression
  • Integration of transcriptomics and proteomics datasets in neurodegeneration
  • Drug Pharmacomicrobiomics web portal (database project, 2018)

Publications

  • Ferrari V, Tedesco B, Cozzi M, … Mohamed A, Poletti A.
    Lysosome quality control in health and neurodegenerative diseases.
    Cell Mol Biol Lett (2024).

  • Cozzi M, Tedesco B, Ferrari V, … Mohamed A, Poletti A.
    One gene, many phenotypes: the role of KIF5A in neurodegeneration.
    Cell Commun Signal (2025).

  • Chierichetti M, Cristofani R, Crippa V, … Mohamed A, Poletti A.
    Small heat shock protein B8: from cell functions to therapeutic applications.
    Neural Regen Res (2025).

  • Cristofani R, Tedesco B, Ferrari V, … Mohamed A, Poletti A.
    Targeting androgen receptor stability in SBMA.
    Cell Commun Signal (2025).

Full list on ORCID


Awards

  • Excellence Scholarship – University of Milan
  • Best Graduation Project – October 6 University
  • Several recognitions in clinical skills, counseling, and research competitions

Contact


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