diff --git a/.github/workflows/wheel-aarch64.yaml b/.github/workflows/wheel-aarch64.yaml
new file mode 100644
index 00000000..22edf057
--- /dev/null
+++ b/.github/workflows/wheel-aarch64.yaml
@@ -0,0 +1,52 @@
+name: Wheels AArch64
+
+on:
+  push:
+    tags:
+      - "v*"
+
+jobs:
+  build_wheels:
+    name: Build wheel on ${{matrix.arch}} for ${{ matrix.os }}
+    runs-on: ${{ matrix.os }}
+    strategy:
+      fail-fast: false
+      matrix:
+        os: [ubuntu-latest]
+        arch: [aarch64]
+    env:
+      CIBW_ARCHS_LINUX: ${{matrix.arch}}
+      CIBW_TEST_COMMAND: pytest --pyargs numcodecs
+      CIBW_TEST_REQUIRES: pytest
+      CIBW_SKIP: "pp* cp36-* *-musllinux_* *win32 *_i686 *_s390x"
+      CIBW_ENVIRONMENT: "DISABLE_NUMCODECS_AVX2=1 DISABLE_NUMCODECS_SSE2=1"
+
+    steps:
+      - uses: actions/checkout@v3
+        with:
+          submodules: true
+
+      - uses: docker/setup-qemu-action@v1
+        name: Set up QEMU
+
+      - uses: pypa/cibuildwheel@v2.12.0
+
+      - uses: actions/upload-artifact@v3
+        with:
+          name: wheels
+          path: ./wheelhouse
+
+  upload_pypi:
+    needs: [build_wheels]
+    runs-on: ubuntu-latest
+    steps:
+      - uses: actions/download-artifact@v3
+        with:
+          name: wheels
+          path: dist
+
+      - uses: pypa/gh-action-pypi-publish@master
+        with:
+          user: __token__
+          password: ${{ secrets.pypi_password }}
+          # To test: repository_url: https://test.pypi.org/legacy/
diff --git a/docs/release.rst b/docs/release.rst
index d7211436..a5995bb3 100644
--- a/docs/release.rst
+++ b/docs/release.rst
@@ -31,6 +31,9 @@ Maintenance
 * Cleanup ``import``s in ``adhoc/blosc_memleak_check.py``
   By :user:`John Kirkham <jakirkham>`, :issue:`408`.
 
+* Build wheels for Linux AArch64 on verison release.
+  By :user:`Jeremy Hetzel <jthetzel>`, :issue:`315`.
+
 .. _release_0.11.0:
 
 0.11.0
diff --git a/setup.py b/setup.py
index f07cf8d4..1b0563c9 100644
--- a/setup.py
+++ b/setup.py
@@ -3,6 +3,7 @@
 from glob import glob
 
 import cpuinfo
+import platform
 from Cython.Distutils.build_ext import new_build_ext as build_ext
 from setuptools import Extension, setup
 from setuptools.errors import CCompilerError, ExecError, PlatformError
@@ -21,6 +22,8 @@
 if have_cflags:
     # respect compiler options set by user
     pass
+elif platform.machine() == 'aarch64':
+    pass
 elif os.name == 'posix':
     if disable_sse2:
         base_compile_args.append('-mno-sse2')