diff --git a/lmdk/libraries/dummy/dummy_mtl.toml b/lmdk/libraries/dummy/dummy_mtl.toml
index 3094e10f3396..58b3820331fa 100644
--- a/lmdk/libraries/dummy/dummy_mtl.toml
+++ b/lmdk/libraries/dummy/dummy_mtl.toml
@@ -60,7 +60,7 @@ count = 1
 
 	[[module.entry]]
 	name = "DUMMY"
-	uuid = "01010101-0101-0101-0101-010101010101"
+	uuid = "01234567-89AB-CDEF-0102-030405060708"
 	affinity_mask = "0x1"
 	instance_count = "15"
 	domain_types = "0"
diff --git a/lmdk/modules/dummy/dummy.c b/lmdk/modules/dummy/dummy.c
index 7c9f49289542..de126062bad0 100644
--- a/lmdk/modules/dummy/dummy.c
+++ b/lmdk/modules/dummy/dummy.c
@@ -18,7 +18,8 @@ __attribute__((section(".module")))
 const struct sof_man_module_manifest dummy_module_manifest = {
 	.module = {
 		.name = "DUMMY",
-		.uuid = {1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1},
+		.uuid = { 0x01234567, 0x89AB, 0xCDEF, { 0x01, 0x02, 0x03, 0x04, 0x05, 0x06, 0x07,
+			  0x08 }},
 		.entry_point = (uint32_t)dummyPackageEntryPoint,
 		.type = {
 			.load_type = SOF_MAN_MOD_TYPE_MODULE,
diff --git a/src/audio/aria/aria.c b/src/audio/aria/aria.c
index 7fe6e319e79a..85dc7b64719f 100644
--- a/src/audio/aria/aria.c
+++ b/src/audio/aria/aria.c
@@ -319,13 +319,10 @@ SOF_MODULE_INIT(aria, sys_comp_module_aria_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_ARIA 0x6D, 0x16, 0xF7, 0x99, 0x2C, 0x37, 0xEF, 0x43, 0xF6, 0x81, \
-	0x22, 0x00, 0x7A, 0xA1, 0x5F, 0x03
-
 SOF_LLEXT_MOD_ENTRY(aria, &aria_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("ARIA", aria_llext_entry, 1, UUID_ARIA, 8);
+	SOF_LLEXT_MODULE_MANIFEST("ARIA", aria_llext_entry, 1, SOF_REG_UUID(aria), 8);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/asrc/asrc.c b/src/audio/asrc/asrc.c
index 45a0acc81bfb..ea72e50bf92d 100644
--- a/src/audio/asrc/asrc.c
+++ b/src/audio/asrc/asrc.c
@@ -879,12 +879,10 @@ SOF_MODULE_INIT(asrc, sys_comp_module_asrc_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_ASRC 0x2d, 0x40, 0xb4, 0x66, 0x68, 0xb4, 0xf2, 0x42, \
-		  0x81, 0xa7, 0xb3, 0x71, 0x21, 0x86, 0x3d, 0xd4
 SOF_LLEXT_MOD_ENTRY(asrc, &asrc_interface);
 
 static const struct sof_man_module_manifest mod_manifest[] __section(".module") __used = {
-	SOF_LLEXT_MODULE_MANIFEST("ASRC", asrc_llext_entry, 1, UUID_ASRC, 2),
+	SOF_LLEXT_MODULE_MANIFEST("ASRC", asrc_llext_entry, 1, SOF_REG_UUID(asrc4), 2),
 };
 
 SOF_LLEXT_BUILDINFO;
diff --git a/src/audio/codec/dts/dts.c b/src/audio/codec/dts/dts.c
index c61ac2b8ef00..0563ea130599 100644
--- a/src/audio/codec/dts/dts.c
+++ b/src/audio/codec/dts/dts.c
@@ -478,13 +478,10 @@ SOF_MODULE_INIT(dts, sys_comp_module_dts_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_DTS 0x4F, 0xC3, 0x5F, 0xD9, 0x0F, 0x37, 0xC7, 0x4A, 0x86, 0xBC, \
-		0xBF, 0xDC, 0x5B, 0xE2, 0x41, 0xE6
-
 SOF_LLEXT_MOD_ENTRY(dts, &dts_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("DTS", dts_llext_entry, 1, UUID_DTS, 40);
+	SOF_LLEXT_MODULE_MANIFEST("DTS", dts_llext_entry, 1, SOF_REG_UUID(dts), 40);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/crossover/crossover.c b/src/audio/crossover/crossover.c
index dae27ff12b56..3c91c329a2f4 100644
--- a/src/audio/crossover/crossover.c
+++ b/src/audio/crossover/crossover.c
@@ -639,13 +639,10 @@ SOF_MODULE_INIT(crossover, sys_comp_module_crossover_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_CROSSOVER 0xD1, 0x9A, 0x8C, 0x94, 0x6A, 0x80, 0x31, 0x41, 0x6C, 0xAD, \
-		0xB2, 0xBD, 0xA9, 0xE3, 0x5A, 0x9F
-
 SOF_LLEXT_MOD_ENTRY(crossover, &crossover_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("XOVER", crossover_llext_entry, 1, UUID_CROSSOVER, 40);
+	SOF_LLEXT_MODULE_MANIFEST("XOVER", crossover_llext_entry, 1, SOF_REG_UUID(crossover), 40);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/dcblock/dcblock.c b/src/audio/dcblock/dcblock.c
index 4d4888d8b4f8..180a71099825 100644
--- a/src/audio/dcblock/dcblock.c
+++ b/src/audio/dcblock/dcblock.c
@@ -264,13 +264,10 @@ SOF_MODULE_INIT(dcblock, sys_comp_module_dcblock_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_DCBLOCK 0xAF, 0xEF, 0x09, 0xB8, 0x81, 0x56, 0xB1, 0x42, 0xD6, 0x9E, \
-		0x04, 0xBB, 0x01, 0x2D, 0xD3, 0x84
-
 SOF_LLEXT_MOD_ENTRY(dcblock, &dcblock_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("DCBLOCK", dcblock_llext_entry, 1, UUID_DCBLOCK, 40);
+	SOF_LLEXT_MODULE_MANIFEST("DCBLOCK", dcblock_llext_entry, 1, SOF_REG_UUID(dcblock), 40);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/drc/drc.c b/src/audio/drc/drc.c
index 000e804cbd00..04734a2384d4 100644
--- a/src/audio/drc/drc.c
+++ b/src/audio/drc/drc.c
@@ -410,13 +410,10 @@ SOF_MODULE_INIT(drc, sys_comp_module_drc_interface_init);
 #include <module/module/api_ver.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_DRC 0xda, 0xe4, 0x6e, 0xb3, 0x6f, 0x00, 0xf9, 0x47, \
-		 0xa0, 0x6d, 0xfe, 0xcb, 0xe2, 0xd8, 0xb6, 0xce
-
 SOF_LLEXT_MOD_ENTRY(drc, &drc_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("DRC", drc_llext_entry, 1, UUID_DRC, 40);
+	SOF_LLEXT_MODULE_MANIFEST("DRC", drc_llext_entry, 1, SOF_REG_UUID(drc), 40);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/eq_fir/eq_fir.c b/src/audio/eq_fir/eq_fir.c
index b02c104cdf89..3380d79047de 100644
--- a/src/audio/eq_fir/eq_fir.c
+++ b/src/audio/eq_fir/eq_fir.c
@@ -488,13 +488,10 @@ SOF_MODULE_INIT(eq_fir, sys_comp_module_eq_fir_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_EQFIR 0xe7, 0x0c, 0xa9, 0x43, 0xa5, 0xf3, 0xdf, 0x41, \
-		 0xac, 0x06, 0xba, 0x98, 0x65, 0x1a, 0xe6, 0xa3
-
 SOF_LLEXT_MOD_ENTRY(eq_fir, &eq_fir_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("EQFIR", eq_fir_llext_entry, 1, UUID_EQFIR, 40);
+	SOF_LLEXT_MODULE_MANIFEST("EQFIR", eq_fir_llext_entry, 1, SOF_REG_UUID(eq_fir), 40);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/eq_iir/eq_iir.c b/src/audio/eq_iir/eq_iir.c
index e11d9454433b..96d4899ed643 100644
--- a/src/audio/eq_iir/eq_iir.c
+++ b/src/audio/eq_iir/eq_iir.c
@@ -258,13 +258,10 @@ SOF_MODULE_INIT(eq_iir, sys_comp_module_eq_iir_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_EQIIR 0xE6, 0xC0, 0x50, 0x51, 0xF9, 0x27, 0xC8, 0x4E, \
-		0x83, 0x51, 0xC7, 0x05, 0xB6, 0x42, 0xD1, 0x2F
-
 SOF_LLEXT_MOD_ENTRY(eq_iir, &eq_iir_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("EQIIR", eq_iir_llext_entry, 1, UUID_EQIIR, 40);
+	SOF_LLEXT_MODULE_MANIFEST("EQIIR", eq_iir_llext_entry, 1, SOF_REG_UUID(eq_iir), 40);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/google/google_ctc_audio_processing.c b/src/audio/google/google_ctc_audio_processing.c
index 12ecac66f8a7..8639e598dd04 100644
--- a/src/audio/google/google_ctc_audio_processing.c
+++ b/src/audio/google/google_ctc_audio_processing.c
@@ -466,14 +466,11 @@ SOF_MODULE_INIT(google_ctc_audio_processing,
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_GOOGLE_CTC 0xBC, 0x1B, 0x0E, 0xBF, 0x6A, 0xDC, 0xFE, 0x45, 0x90, 0xBC, \
-	 0x25, 0x54, 0xCB, 0x13, 0x7A, 0xB4
-
 SOF_LLEXT_MOD_ENTRY(google_ctc_audio_processing, &google_ctc_audio_processing_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
 	SOF_LLEXT_MODULE_MANIFEST("CTC", google_ctc_audio_processing_llext_entry,
-				  1, UUID_GOOGLE_CTC, 40);
+				  1, SOF_REG_UUID(google_ctc_audio_processing), 40);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/google/google_rtc_audio_processing.c b/src/audio/google/google_rtc_audio_processing.c
index c84cadb4c5c8..da673b7e52fa 100644
--- a/src/audio/google/google_rtc_audio_processing.c
+++ b/src/audio/google/google_rtc_audio_processing.c
@@ -861,14 +861,11 @@ SOF_MODULE_INIT(google_rtc_audio_processing,
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_GOOGLE_RTC_AEC 0xA6, 0xA0, 0x80, 0xB7, 0x9F, 0x26, 0x6F, 0x46, 0x77, 0xB4, \
-		 0x23, 0xDF, 0xA0, 0x5A, 0xF7, 0x58
-
 SOF_LLEXT_MOD_ENTRY(google_rtc_audio_processing, &google_rtc_audio_processing_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
 	SOF_LLEXT_MODULE_MANIFEST("RTC_AEC", google_rtc_audio_processing_llext_entry,
-				  7, UUID_GOOGLE_RTC_AEC, 1);
+				  7, SOF_REG_UUID(google_rtc_audio_processing), 1);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/igo_nr/igo_nr.c b/src/audio/igo_nr/igo_nr.c
index 78eead2b1e97..1750b5972508 100644
--- a/src/audio/igo_nr/igo_nr.c
+++ b/src/audio/igo_nr/igo_nr.c
@@ -893,13 +893,10 @@ SOF_MODULE_INIT(igo_nr, sys_comp_module_igo_nr_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_IGO_NR 0xBC, 0xE2, 0x6A, 0x69, 0x77, 0x28, 0xEB, 0x11, 0xC1, 0xAD, \
-		0x02, 0x42, 0xAC, 0x12, 0x00, 0x02
-
 SOF_LLEXT_MOD_ENTRY(igo_nr, &igo_nr_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("IGO_NR", igo_nr_llext_entry, 1, UUID_IGO_NR, 40);
+	SOF_LLEXT_MODULE_MANIFEST("IGO_NR", igo_nr_llext_entry, 1, SOF_REG_UUID(igo_nr), 40);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/mfcc/mfcc.c b/src/audio/mfcc/mfcc.c
index 964b4bae7d38..489df60c40b3 100644
--- a/src/audio/mfcc/mfcc.c
+++ b/src/audio/mfcc/mfcc.c
@@ -266,13 +266,10 @@ SOF_MODULE_INIT(mfcc, sys_comp_module_mfcc_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_MFCC 0x73, 0xA7, 0x10, 0xDB, 0xA4, 0x1A, 0xEA, 0x4C, 0x1F, 0xA2, \
-		0x2D, 0x57, 0xA5, 0xC9, 0x82, 0xEB
-
 SOF_LLEXT_MOD_ENTRY(mfcc, &mfcc_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("MFCC", mfcc_llext_entry, 1, UUID_MFCC, 40);
+	SOF_LLEXT_MODULE_MANIFEST("MFCC", mfcc_llext_entry, 1, SOF_REG_UUID(mfcc), 40);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/mixin_mixout/mixin_mixout.c b/src/audio/mixin_mixout/mixin_mixout.c
index 94a61c89d097..fe9120946dec 100644
--- a/src/audio/mixin_mixout/mixin_mixout.c
+++ b/src/audio/mixin_mixout/mixin_mixout.c
@@ -949,18 +949,13 @@ SOF_MODULE_INIT(mixout, sys_comp_module_mixout_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_MIXIN 0xB2, 0x6E, 0x65, 0x39, 0x71, 0x3B, 0x49, 0x40, \
-		0x8D, 0x3F, 0xF9, 0x2C, 0xD5, 0xC4, 0x3C, 0x09
-#define UUID_MIXOUT 0x5A, 0x50, 0x56, 0x3C, 0xD7, 0x24, 0x8F, 0x41, \
-		0xBD, 0xDC, 0xC1, 0xF5, 0xA3, 0xAC, 0x2A, 0xE0
-
 SOF_LLEXT_MOD_ENTRY(mixin, &mixin_interface);
 SOF_LLEXT_MOD_ENTRY(mixout, &mixout_interface);
 
 static const struct sof_man_module_manifest mod_manifest[] __section(".module") __used =
 {
-	SOF_LLEXT_MODULE_MANIFEST("MIXIN", mixin_llext_entry, 1, UUID_MIXIN, 30),
-	SOF_LLEXT_MODULE_MANIFEST("MIXOUT", mixout_llext_entry, 1, UUID_MIXOUT, 30),
+	SOF_LLEXT_MODULE_MANIFEST("MIXIN", mixin_llext_entry, 1, SOF_REG_UUID(mixin), 30),
+	SOF_LLEXT_MODULE_MANIFEST("MIXOUT", mixout_llext_entry, 1, SOF_REG_UUID(mixout), 30),
 };
 
 SOF_LLEXT_BUILDINFO;
diff --git a/src/audio/module_adapter/module/waves/waves.c b/src/audio/module_adapter/module/waves/waves.c
index 4f606fd594dd..ee45c7077405 100644
--- a/src/audio/module_adapter/module/waves/waves.c
+++ b/src/audio/module_adapter/module/waves/waves.c
@@ -907,15 +907,10 @@ SOF_MODULE_INIT(waves, sys_comp_module_waves_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-/* d944281a-afe9-4695-a043-d7f62b89538e */
-#define UUID_WAVES_CODEC 0x1A, 0x28, 0x44, 0xD9, 0xE9, 0xAF, 0x95, 0x46, \
-		0xA0, 0x43, 0xD7, 0xF6, 0x2B, 0x89, 0x53, 0x8E
-
 SOF_LLEXT_MOD_ENTRY(waves, &waves_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("WAVES", waves_llext_entry,
-				  7, UUID_WAVES_CODEC, 8);
+	SOF_LLEXT_MODULE_MANIFEST("WAVES", waves_llext_entry, 7, SOF_REG_UUID(waves), 8);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/multiband_drc/multiband_drc.c b/src/audio/multiband_drc/multiband_drc.c
index 3ffe8e0f511e..f948e3354e33 100644
--- a/src/audio/multiband_drc/multiband_drc.c
+++ b/src/audio/multiband_drc/multiband_drc.c
@@ -426,13 +426,11 @@ SOF_MODULE_INIT(multiband_drc, sys_comp_module_multiband_drc_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_MULTIBAND_DRC 0x56, 0x22, 0x9F, 0x0D, 0x4F, 0x8E, 0xB3, 0x47, 0x48, 0x84, \
-		0x23, 0x9A, 0x33, 0x4F, 0x11, 0x91
-
 SOF_LLEXT_MOD_ENTRY(multiband_drc, &multiband_drc_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("MB_DRC", multiband_drc_llext_entry, 1, UUID_MULTIBAND_DRC, 40);
+	SOF_LLEXT_MODULE_MANIFEST("MB_DRC", multiband_drc_llext_entry, 1,
+				  SOF_REG_UUID(multiband_drc), 40);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/mux/mux.c b/src/audio/mux/mux.c
index 8d65b2b2698d..79280e376220 100644
--- a/src/audio/mux/mux.c
+++ b/src/audio/mux/mux.c
@@ -482,24 +482,20 @@ SOF_MODULE_INIT(demux, sys_comp_module_demux_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_MUX 0x35, 0x6E, 0xCE, 0x64, 0x7A, 0x85, 0x78, 0x48, 0xE8, 0xAC, \
-		0xE2, 0xA2, 0xF4, 0x2E, 0x30, 0x69
 SOF_LLEXT_MOD_ENTRY(mux, &mux_interface);
 
 /*
  * The demux entry is removed because mtl.toml doesn't have an entry
  * for it. Once that is fixed, the manifest line below can be
  * re-activated:
- * #define UUID_DEMUX 0x68, 0x68, 0xB2, 0xC4, 0x30, 0x14, 0x0E, 0x47, 0x89, 0xA0, \
- *		0x15, 0xD1, 0xC7, 0x7F, 0x85, 0x1A
  * SOF_LLEXT_MOD_ENTRY(demux, &demux_interface);
  */
 
 static const struct sof_man_module_manifest mod_manifest[] __section(".module") __used = {
-	SOF_LLEXT_MODULE_MANIFEST("MUX", mux_llext_entry, 1, UUID_MUX, 15),
+	SOF_LLEXT_MODULE_MANIFEST("MUX", mux_llext_entry, 1, SOF_REG_UUID(mux4), 15),
 	/*
 	 * See comment above for a demux deactivation reason
-	 * SOF_LLEXT_MODULE_MANIFEST("DEMUX", demux_llext_entry, 1, UUID_DEMUX, 15),
+	 * SOF_LLEXT_MODULE_MANIFEST("DEMUX", demux_llext_entry, 1, SOF_REG_UUID(demux), 15),
 	 */
 };
 
diff --git a/src/audio/rtnr/rtnr.c b/src/audio/rtnr/rtnr.c
index 830bbde413e7..2f9fabe43d8a 100644
--- a/src/audio/rtnr/rtnr.c
+++ b/src/audio/rtnr/rtnr.c
@@ -876,14 +876,10 @@ SOF_MODULE_INIT(rtnr, sys_comp_module_rtnr_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-/* 5c7ca334-e15d-11eb-ba800242ac130004 */
-#define UUID_RTNR 0x34, 0xA3, 0x7C, 0x5C, 0x5D, 0xE1, 0xEB, 0x11, \
-		0xBA, 0x80, 0x02, 0x42, 0xAC, 0x13, 0x00, 0x04
-
 SOF_LLEXT_MOD_ENTRY(rtnr, &rtnr_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("RTNR", rtnr_llext_entry, 1, UUID_RTNR, 40);
+	SOF_LLEXT_MODULE_MANIFEST("RTNR", rtnr_llext_entry, 1, SOF_REG_UUID(rtnr), 40);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/selector/selector.c b/src/audio/selector/selector.c
index 8032a3d7dea9..9b9ee5f63d03 100644
--- a/src/audio/selector/selector.c
+++ b/src/audio/selector/selector.c
@@ -923,13 +923,11 @@ SOF_MODULE_INIT(selector, sys_comp_module_selector_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_SELECTOR 0x32, 0xFE, 0x92, 0xC1, 0x17, 0x1E, 0xC2, 0x4F, 0x58, 0x97, \
-		0xC7, 0xF3, 0x54, 0x2E, 0x98, 0x0A
-
 SOF_LLEXT_MOD_ENTRY(selector, &selector_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("MICSEL", selector_llext_entry, 1, UUID_SELECTOR, 8);
+	SOF_LLEXT_MODULE_MANIFEST("MICSEL", selector_llext_entry, 1, SOF_REG_UUID(selector4),
+				  8);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/src/src.c b/src/audio/src/src.c
index d75b1eb53822..68718f747400 100644
--- a/src/audio/src/src.c
+++ b/src/audio/src/src.c
@@ -89,21 +89,18 @@ SOF_MODULE_INIT(src, sys_comp_module_src_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_SRC 0x8D, 0xB2, 0x1B, 0xE6, 0x9A, 0x14, 0x1F, 0x4C, \
-		 0xB7, 0x09, 0x46, 0x82, 0x3E, 0xF5, 0xF5, 0xAE
 SOF_LLEXT_MOD_ENTRY(src, &src_interface);
 
 #if CONFIG_COMP_SRC_LITE
-#define UUID_SRC_LITE 0x51, 0x10, 0x44, 0x33, 0xCD, 0x44, 0x6A, 0x46, \
-		      0x83, 0xA3, 0x17, 0x84, 0x78, 0x70, 0x8A, 0xEA
 extern const struct module_interface src_lite_interface;
 SOF_LLEXT_MOD_ENTRY(src_lite, &src_lite_interface);
 #endif
 
 static const struct sof_man_module_manifest mod_manifest[] __section(".module") __used = {
-	SOF_LLEXT_MODULE_MANIFEST("SRC", src_llext_entry, 1, UUID_SRC, 1),
+	SOF_LLEXT_MODULE_MANIFEST("SRC", src_llext_entry, 1, SOF_REG_UUID(src4), 1),
 #if CONFIG_COMP_SRC_LITE
-	SOF_LLEXT_MODULE_MANIFEST("SRC_LITE", src_lite_llext_entry, 1, UUID_SRC_LITE, 1),
+	SOF_LLEXT_MODULE_MANIFEST("SRC_LITE", src_lite_llext_entry, 1, SOF_REG_UUID(src_lite),
+				  1),
 #endif
 };
 
diff --git a/src/audio/tdfb/tdfb.c b/src/audio/tdfb/tdfb.c
index dbb99bddb5aa..39f47a61527d 100644
--- a/src/audio/tdfb/tdfb.c
+++ b/src/audio/tdfb/tdfb.c
@@ -831,13 +831,10 @@ SOF_MODULE_INIT(tdfb, sys_comp_module_tdfb_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_TDFB 0x49, 0x17, 0x51, 0xdd, 0xfa, 0xd9, 0x5c, 0x45, 0xb3, 0xa7, \
-		  0x13, 0x58, 0x56, 0x93, 0xf1, 0xaf
-
 SOF_LLEXT_MOD_ENTRY(tdfb, &tdfb_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("TDFB", tdfb_llext_entry, 1, UUID_TDFB, 40);
+	SOF_LLEXT_MODULE_MANIFEST("TDFB", tdfb_llext_entry, 1, SOF_REG_UUID(tdfb), 40);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/audio/volume/volume.c b/src/audio/volume/volume.c
index b3cf42cf116a..a92f9ccf9047 100644
--- a/src/audio/volume/volume.c
+++ b/src/audio/volume/volume.c
@@ -820,23 +820,19 @@ SOF_MODULE_INIT(gain, sys_comp_module_gain_interface_init);
 #include <rimage/sof/user/manifest.h>
 
 #if CONFIG_COMP_PEAK_VOL
-#define UUID_PEAKVOL 0x23, 0x13, 0x17, 0x8a, 0xa3, 0x94, 0x1d, 0x4e, \
-		     0xaf, 0xe9, 0xfe, 0x5d, 0xba, 0xa4, 0xc3, 0x93
 SOF_LLEXT_MOD_ENTRY(peakvol, &volume_interface);
 #endif
 
 #if CONFIG_COMP_GAIN
-#define UUID_GAIN 0xa8, 0xa9, 0xbc, 0x61, 0xd0, 0x18, 0x18, 0x4a, \
-		  0x8e, 0x7b, 0x26, 0x39, 0x21, 0x98, 0x04, 0xb7
 SOF_LLEXT_MOD_ENTRY(gain, &gain_interface);
 #endif
 
 static const struct sof_man_module_manifest mod_manifest[] __section(".module") __used = {
 #if CONFIG_COMP_PEAK_VOL
-	SOF_LLEXT_MODULE_MANIFEST("PEAKVOL", peakvol_llext_entry, 1, UUID_PEAKVOL, 10),
+	SOF_LLEXT_MODULE_MANIFEST("PEAKVOL", peakvol_llext_entry, 1, SOF_REG_UUID(volume), 10),
 #endif
 #if CONFIG_COMP_GAIN
-	SOF_LLEXT_MODULE_MANIFEST("GAIN", gain_llext_entry, 1, UUID_GAIN, 40),
+	SOF_LLEXT_MODULE_MANIFEST("GAIN", gain_llext_entry, 1, SOF_REG_UUID(gain), 40),
 #endif
 };
 
diff --git a/src/include/module/module/llext.h b/src/include/module/module/llext.h
index 05b8f0ffb5f5..e1d294694280 100644
--- a/src/include/module/module/llext.h
+++ b/src/include/module/module/llext.h
@@ -10,7 +10,7 @@
 { \
 	.module = { \
 		.name = manifest_name, \
-		.uuid = {mod_uuid},			  \
+		.uuid = mod_uuid, \
 		.entry_point = (uint32_t)(entry), \
 		.instance_max_count = instances, \
 		.type = { \
diff --git a/src/include/sof/ipc/topology.h b/src/include/sof/ipc/topology.h
index 5726b7055b32..5605c6ef9837 100644
--- a/src/include/sof/ipc/topology.h
+++ b/src/include/sof/ipc/topology.h
@@ -50,7 +50,7 @@ struct ipc_comp_dev;
 const struct comp_driver *ipc4_get_comp_drv(uint32_t module_id);
 struct comp_dev *ipc4_get_comp_dev(uint32_t comp_id);
 int ipc4_add_comp_dev(struct comp_dev *dev);
-const struct comp_driver *ipc4_get_drv(const uint8_t *uuid);
+const struct comp_driver *ipc4_get_drv(const void *uuid);
 int ipc4_chain_manager_create(struct ipc4_chain_dma *cdma);
 int ipc4_chain_dma_state(struct comp_dev *dev, struct ipc4_chain_dma *cdma);
 int ipc4_create_chain_dma(struct ipc *ipc, struct ipc4_chain_dma *cdma);
diff --git a/src/include/sof/lib/uuid.h b/src/include/sof/lib/uuid.h
index 7c7691bfff38..d45f821613d7 100644
--- a/src/include/sof/lib/uuid.h
+++ b/src/include/sof/lib/uuid.h
@@ -50,13 +50,19 @@
  * pass UUIDs as a linear array of bytes, only one endianness will
  * work.  If SOF ever ships on a BE system all use of sof_uuid will
  * need to be modified to byte swap the a/b/c values.
+ *
+ * Some identifiers are taken from the module manifest. Since the module
+ * manifest structure (sof_man_module) is marked as packed, the pointer
+ * to the sof_uuid structure may not be properly aligned. To avoid possible
+ * problems with accessing fields of this structure from unaligned addresses,
+ * it has been marked as packed.
  */
 struct sof_uuid {
 	uint32_t a;
 	uint16_t b;
 	uint16_t c;
 	uint8_t  d[8];
-};
+} __packed;
 
 #define _UUID_INIT(va, vb, vc, d0, d1, d2, d3, d4, d5, d6, d7) \
 	{ va, vb, vc, { d0, d1, d2, d3, d4, d5, d6, d7 } }
@@ -126,6 +132,14 @@ struct sof_uuid_entry {
 	_DEF_UUID(entity_name, uuid_name,			\
 		  _UUID_INIT(va, vb, vc, vd0, vd1, vd2, vd3, vd4, vd5, vd6, vd7))
 
+/** \brief Get UUID value sourced from the fixed SOF registry
+ *
+ * The ID value is sourced by name from the uuid-registry.txt file distributed with the source tree.
+ *
+ * \param name Name of the UUID, must match an entry in uuid-registry.txt
+ */
+#define SOF_REG_UUID(name) _UUIDREG_##name
+
 /** \brief Defines UUID sourced from the fixed SOF registry
  *
  * As for SOF_DEFINE_UUID(), but the ID value is sourced by name from
@@ -136,7 +150,7 @@ struct sof_uuid_entry {
  *
  * \param name Name of the UUID, must match an entry in uuid-registry.txt
  */
-#define SOF_DEFINE_REG_UUID(name) _DEF_UUID(#name, name##_uuid, _UUIDREG_##name)
+#define SOF_DEFINE_REG_UUID(name) _DEF_UUID(#name, name##_uuid, SOF_REG_UUID(name))
 
 /** \brief Creates local unique 32-bit representation of UUID structure.
  *
diff --git a/src/ipc/ipc4/helper.c b/src/ipc/ipc4/helper.c
index 0dfb4bc73fc2..3e8cfdcf5815 100644
--- a/src/ipc/ipc4/helper.c
+++ b/src/ipc/ipc4/helper.c
@@ -93,7 +93,7 @@ static inline char *ipc4_get_comp_new_data(void)
 
 static const struct comp_driver *ipc4_library_get_comp_drv(char *data)
 {
-	return ipc4_get_drv((const uint8_t *)data);
+	return ipc4_get_drv(data);
 }
 #else
 static inline char *ipc4_get_comp_new_data(void)
@@ -773,7 +773,7 @@ int ipc4_chain_manager_create(struct ipc4_chain_dma *cdma)
 	const struct comp_driver *drv;
 	struct comp_dev *dev;
 
-	drv = ipc4_get_drv((const uint8_t *)&uuid);
+	drv = ipc4_get_drv(&uuid);
 	if (!drv)
 		return -EINVAL;
 
@@ -912,8 +912,9 @@ int ipc4_process_on_core(uint32_t core, bool blocking)
 	return IPC4_SUCCESS;
 }
 
-const struct comp_driver *ipc4_get_drv(const uint8_t *uuid)
+const struct comp_driver *ipc4_get_drv(const void *uuid)
 {
+	const struct sof_uuid *const sof_uuid = (const struct sof_uuid *)uuid;
 	struct comp_driver_list *drivers = comp_drivers_get();
 	struct list_item *clist;
 	const struct comp_driver *drv = NULL;
@@ -936,11 +937,11 @@ const struct comp_driver *ipc4_get_drv(const uint8_t *uuid)
 		}
 	}
 
-	tr_warn(&comp_tr, "get_drv(): the provided UUID (%08x %08x %08x %08x) can't be found!",
-		*(uint32_t *)(&uuid[0]),
-		*(uint32_t *)(&uuid[4]),
-		*(uint32_t *)(&uuid[8]),
-		*(uint32_t *)(&uuid[12]));
+	tr_warn(&comp_tr,
+		"get_drv(): the provided UUID (%08x-%04x-%04x-%02x%02x-%02x%02x%02x%02x%02x%02x) can't be found!",
+		sof_uuid->a, sof_uuid->b, sof_uuid->c, sof_uuid->d[0], sof_uuid->d[1],
+		sof_uuid->d[2], sof_uuid->d[3], sof_uuid->d[4], sof_uuid->d[5], sof_uuid->d[6],
+		sof_uuid->d[7]);
 
 out:
 	irq_local_enable(flags);
@@ -998,13 +999,13 @@ const struct comp_driver *ipc4_get_comp_drv(uint32_t module_id)
 #endif
 	}
 	/* Check already registered components */
-	drv = ipc4_get_drv(mod->uuid);
+	drv = ipc4_get_drv(&mod->uuid);
 
 #if CONFIG_LIBRARY_MANAGER
 	if (!drv) {
 		/* New module not registered yet. */
 		lib_manager_register_module(module_id);
-		drv = ipc4_get_drv(mod->uuid);
+		drv = ipc4_get_drv(&mod->uuid);
 	}
 #endif
 
diff --git a/src/library_manager/lib_manager.c b/src/library_manager/lib_manager.c
index ae824d512dc5..c208fde81988 100644
--- a/src/library_manager/lib_manager.c
+++ b/src/library_manager/lib_manager.c
@@ -641,7 +641,7 @@ int lib_manager_register_module(const uint32_t component_id)
 	}
 
 	mod = (struct sof_man_module *)((const uint8_t *)desc + SOF_MAN_MODULE_OFFSET(entry_index));
-	const struct sof_uuid *uid = (struct sof_uuid *)&mod->uuid[0];
+	const struct sof_uuid *uid = (struct sof_uuid *)&mod->uuid;
 
 	lib_manager_prepare_module_adapter(drv, uid);
 
diff --git a/src/probe/probe.c b/src/probe/probe.c
index 190633c34ec8..4ca71685d7db 100644
--- a/src/probe/probe.c
+++ b/src/probe/probe.c
@@ -1620,13 +1620,10 @@ SOF_MODULE_INIT(probe, sys_comp_module_probe_interface_init);
 #include <module/module/llext.h>
 #include <rimage/sof/user/manifest.h>
 
-#define UUID_PROBE 0x08, 0x08, 0xAD, 0x7C, 0x10, 0xAB, 0x23, 0xCD, 0xEF, 0x45, \
-		0x12, 0xAB, 0x34, 0xCD, 0x56, 0xEF,
-
 SOF_LLEXT_MOD_ENTRY(probe, &probe_interface);
 
 static const struct sof_man_module_manifest mod_manifest __section(".module") __used =
-	SOF_LLEXT_MODULE_MANIFEST("PROBE", probe_llext_entry, 1, UUID_PROBE, 40);
+	SOF_LLEXT_MODULE_MANIFEST("PROBE", probe_llext_entry, 1, SOF_REG_UUID(probe4), 40);
 
 SOF_LLEXT_BUILDINFO;
 
diff --git a/src/samples/audio/smart_amp_test_ipc4.c b/src/samples/audio/smart_amp_test_ipc4.c
index 41d8ff2db25a..3d1cd244cc6a 100644
--- a/src/samples/audio/smart_amp_test_ipc4.c
+++ b/src/samples/audio/smart_amp_test_ipc4.c
@@ -408,8 +408,8 @@ SOF_LLEXT_MOD_ENTRY(smart_amp_test, &smart_amp_test_interface);
 static const struct sof_man_module_manifest main_manifest __section(".module") __attribute__((used)) = {
 	.module = {
 		.name = "SMATEST",
-		.uuid = {0x1E, 0x96, 0x7A, 0x16, 0xE4, 0x8A, 0xEA, 0x11,
-			 0x89, 0xF1, 0x00, 0x0C, 0x29, 0xCE, 0x16, 0x35},
+		.uuid = { 0x167A961E, 0x8AE4, 0x11EA, { 0x89, 0xF1, 0x00, 0x0C, 0x29, 0xCE, 0x16,
+			  0x35 }},
 		.entry_point = (uint32_t)smart_amp_test_llext_entry,
 		.instance_max_count = 1,
 		.type = {
diff --git a/tools/rimage/src/adsp_config.c b/tools/rimage/src/adsp_config.c
index 7dd30864ff54..5ce44a689826 100644
--- a/tools/rimage/src/adsp_config.c
+++ b/tools/rimage/src/adsp_config.c
@@ -1910,7 +1910,7 @@ static int parse_module(const toml_table_t *toml, struct parse_ctx *pctx,
 		if (ret < 0)
 			return err_key_parse("uuid", NULL);
 
-		parse_uuid(buf, mod_man->uuid);
+		parse_uuid(buf, &mod_man->uuid);
 
 		mod_man->affinity_mask = parse_uint32_hex_key(mod_entry, &ctx_entry,
 							      "affinity_mask", 1, &ret);
@@ -1952,7 +1952,7 @@ static int parse_module(const toml_table_t *toml, struct parse_ctx *pctx,
 		header->version_major = 2;
 		header->version_minor = 5;
 		header->ext_module_config_length = sizeof(struct fw_ext_mod_config_header);
-		memcpy(header->guid, mod_man->uuid, sizeof(mod_man->uuid));
+		memcpy(header->guid, &mod_man->uuid, sizeof(mod_man->uuid));
 
 		type = parse_uint32_hex_key(mod_entry, &ctx_entry, "module_type", 1, &ret);
 		if (ret < 0)
diff --git a/tools/rimage/src/include/rimage/sof/user/manifest.h b/tools/rimage/src/include/rimage/sof/user/manifest.h
index 829b1b134810..c206fe7a5055 100644
--- a/tools/rimage/src/include/rimage/sof/user/manifest.h
+++ b/tools/rimage/src/include/rimage/sof/user/manifest.h
@@ -86,13 +86,20 @@ struct sof_man_segment_desc {
 #define SOF_MAN_MOD_SHA384_LEN		48
 #define SOF_MAN_MOD_ID			{'$', 'A', 'M', 'E'}
 
+struct sof_man_uuid {
+	uint32_t a;
+	uint16_t b;
+	uint16_t c;
+	uint8_t  d[8];
+};
+
 /*
  * Each module has an entry in the FW header. Used by ROM - Immutable.
  */
 struct sof_man_module {
 	uint8_t struct_id[SOF_MAN_MOD_ID_LEN];	/* SOF_MAN_MOD_ID */
 	uint8_t name[SOF_MAN_MOD_NAME_LEN];
-	uint8_t uuid[16];
+	struct sof_man_uuid uuid;
 	struct sof_man_module_type type;
 	uint8_t hash[SOF_MAN_MOD_SHA256_LEN];
 	uint32_t entry_point;
diff --git a/tools/rimage/src/include/rimage/toml_utils.h b/tools/rimage/src/include/rimage/toml_utils.h
index 22f257c2c65d..94c512f31aa0 100644
--- a/tools/rimage/src/include/rimage/toml_utils.h
+++ b/tools/rimage/src/include/rimage/toml_utils.h
@@ -115,7 +115,7 @@ void parse_str_key(const toml_table_t *table, struct parse_ctx *ctx, const char
  * Parse UUID hex string into a byte array. The endianness of the output
  * is architecture-dependent: do not use in any portable code.
  */
-void parse_uuid(const char *buf, uint8_t *uuid);
+void parse_uuid(const char *buf, void *uuid);
 
 /** version is stored as toml array with integer number, something like:
  *   "version = [1, 8]"
diff --git a/tools/rimage/src/manifest.c b/tools/rimage/src/manifest.c
index d7a1fbe58e4e..f0c92014ce00 100644
--- a/tools/rimage/src/manifest.c
+++ b/tools/rimage/src/manifest.c
@@ -205,7 +205,7 @@ static void man_get_section_manifest(struct image *image,
 	memcpy(man_module->struct_id, "$AME", 4);
 	man_module->entry_point = sof_mod->module.entry_point;
 	memcpy(man_module->name, sof_mod->module.name, SOF_MAN_MOD_NAME_LEN);
-	memcpy(man_module->uuid, sof_mod->module.uuid, 16);
+	memcpy(&man_module->uuid, &sof_mod->module.uuid, sizeof(man_module->uuid));
 	man_module->affinity_mask = sof_mod->module.affinity_mask;
 	man_module->instance_max_count = sof_mod->module.instance_max_count;
 	man_module->type.auto_start = sof_mod->module.type.auto_start;
diff --git a/tools/rimage/src/toml_utils.c b/tools/rimage/src/toml_utils.c
index 7570c5b1f7bb..d7abc1e82296 100644
--- a/tools/rimage/src/toml_utils.c
+++ b/tools/rimage/src/toml_utils.c
@@ -290,7 +290,7 @@ void parse_str_key(const toml_table_t *table, struct parse_ctx *ctx, const char
 	dst[capacity - 1] = 0;
 }
 
-void parse_uuid(const char *buf, uint8_t *uuid)
+void parse_uuid(const char *buf, void *uuid)
 {
 	struct uuid_t id;
 	uint32_t d[11];