download.file("ftp://ftp.jax.org/sanger/current_snps/mgp.v5.merged.snps_all.dbSNP142.vcf.gz", "mgp.v5.merged.snps_all.dbSNP142.vcf.gz", method = "auto", quiet=TRUE) source("https://bioconductor.org/biocLite.R") biocLite("VariantAnnotation") source("https://bioconductor.org/biocLite.R") biocLite("AnnotationHub")