Preprocessing/Hyperparameters of MEC and RNA-Imaging Experiments for SCOTv2

[peterpaohuang]

Hi,

I'm hoping to reproduce the results of SCOTv2 on the MEC and RNA-Imaging datasets. I have a couple of questions:

(1) Where can I gain access to the MEC dataset (there were no links in the paper) and how did you preprocess this data? Was it conducted in the same way as SNARE-seq and scGEM?
(2) I tried replicating the results of the RNA-imaging dataset using SCOTv2's default parameters but was not able to achieve good metrics. Can you share the specific hyperparameters you used for this experiment? Additionally, was there any additional preprocessing that you took after the data loaders provided by https://github.com/uhlerlab/cross-modal-autoencoders/tree/master or did you directly use those tensor representations? For instance, did you do any of the same preprocessing steps you took in SNARE-seq/scGEM for the gene expression profiles of this dataset?

Thank you in advance for your guidance.