diff --git a/.github/workflows/test.yml b/.github/workflows/test.yml
index 675831734..d7143202f 100644
--- a/.github/workflows/test.yml
+++ b/.github/workflows/test.yml
@@ -35,6 +35,7 @@ jobs:
     needs: lint
     runs-on: ${{ matrix.os }}
     strategy:
+      fail-fast: false
       matrix:
         os: [ubuntu-latest, ubuntu-24.04-arm, windows-latest, macos-13, macos-15]
         python_version: ['3.13']
diff --git a/bin/generate_schema.py b/bin/generate_schema.py
index 8ca6a1a76..28538e06f 100755
--- a/bin/generate_schema.py
+++ b/bin/generate_schema.py
@@ -54,21 +54,23 @@
     type: string_array
   build-frontend:
     default: default
-    description: Set the tool to use to build, either "pip" (default for now), "build", or "build[uv]"
+    description: Set the tool to use to build, either "pip" (default for now), "build", "build[uv]", or "uv".
     oneOf:
-      - enum: [pip, build, "build[uv]", default]
+      - enum: [pip, build, "build[uv]", uv, default]
       - type: string
         pattern: '^pip; ?args:'
       - type: string
         pattern: '^build; ?args:'
       - type: string
         pattern: '^build\\[uv\\]; ?args:'
+      - type: string
+        pattern: '^uv; ?args:'
       - type: object
         additionalProperties: false
         required: [name]
         properties:
           name:
-            enum: [pip, build, "build[uv]"]
+            enum: [pip, build, "build[uv]", uv]
           args:
             type: array
             items:
diff --git a/cibuildwheel/frontend.py b/cibuildwheel/frontend.py
index 79796a1be..a856fc42a 100644
--- a/cibuildwheel/frontend.py
+++ b/cibuildwheel/frontend.py
@@ -7,7 +7,7 @@
 from .logger import log
 from .util.helpers import parse_key_value_string
 
-BuildFrontendName = Literal["pip", "build", "build[uv]"]
+BuildFrontendName = Literal["pip", "build", "build[uv]", "uv"]
 
 
 @dataclass(frozen=True)
diff --git a/cibuildwheel/platforms/ios.py b/cibuildwheel/platforms/ios.py
index 3473ef740..fe2c1f281 100644
--- a/cibuildwheel/platforms/ios.py
+++ b/cibuildwheel/platforms/ios.py
@@ -283,7 +283,7 @@ def setup_python(
     build_frontend: BuildFrontendName,
     xbuild_tools: Sequence[str] | None,
 ) -> tuple[Path, dict[str, str]]:
-    if build_frontend == "build[uv]":
+    if build_frontend == "build[uv]" or build_frontend == "uv":
         msg = "uv doesn't support iOS"
         raise errors.FatalError(msg)
 
@@ -439,7 +439,7 @@ def build(options: Options, tmp_path: Path) -> None:
             build_options = options.build_options(config.identifier)
             build_frontend = build_options.build_frontend or BuildFrontendConfig("build")
             # uv doesn't support iOS
-            if build_frontend.name == "build[uv]":
+            if build_frontend.name == "build[uv]" or build_frontend.name == "uv":
                 msg = "uv doesn't support iOS"
                 raise errors.FatalError(msg)
 
diff --git a/cibuildwheel/platforms/linux.py b/cibuildwheel/platforms/linux.py
index 4932298aa..3795a9844 100644
--- a/cibuildwheel/platforms/linux.py
+++ b/cibuildwheel/platforms/linux.py
@@ -204,7 +204,7 @@ def build_in_container(
         local_identifier_tmp_dir = local_tmp_dir / config.identifier
         build_options = options.build_options(config.identifier)
         build_frontend = build_options.build_frontend or BuildFrontendConfig("build")
-        use_uv = build_frontend.name == "build[uv]"
+        use_uv = build_frontend.name in {"build[uv]", "uv"}
         pip = ["uv", "pip"] if use_uv else ["pip"]
 
         log.step("Setting up build environment...")
@@ -303,6 +303,19 @@ def build_in_container(
                     ],
                     env=env,
                 )
+            elif build_frontend.name == "uv":
+                container.call(
+                    [
+                        "uv",
+                        "build",
+                        "--python=python",
+                        container_package_dir,
+                        "--wheel",
+                        f"--out-dir={built_wheel_dir}",
+                        *extra_flags,
+                    ],
+                    env=env,
+                )
             else:
                 assert_never(build_frontend)
 
diff --git a/cibuildwheel/platforms/macos.py b/cibuildwheel/platforms/macos.py
index 428971263..a390061f5 100644
--- a/cibuildwheel/platforms/macos.py
+++ b/cibuildwheel/platforms/macos.py
@@ -199,7 +199,7 @@ def setup_python(
     build_frontend: BuildFrontendName,
 ) -> tuple[Path, dict[str, str]]:
     uv_path = find_uv()
-    use_uv = build_frontend == "build[uv]"
+    use_uv = build_frontend in {"build[uv]", "uv"}
 
     tmp.mkdir()
     implementation_id = python_configuration.identifier.split("-")[0]
@@ -375,6 +375,17 @@ def setup_python(
             *constraint_flags(dependency_constraint),
             env=env,
         )
+    elif build_frontend == "uv":
+        assert uv_path is not None
+        call(
+            uv_path,
+            "pip",
+            "install",
+            "--upgrade",
+            "delocate",
+            *constraint_flags(dependency_constraint),
+            env=env,
+        )
     else:
         assert_never(build_frontend)
 
@@ -407,7 +418,7 @@ def build(options: Options, tmp_path: Path) -> None:
         for config in python_configurations:
             build_options = options.build_options(config.identifier)
             build_frontend = build_options.build_frontend or BuildFrontendConfig("build")
-            use_uv = build_frontend.name == "build[uv]"
+            use_uv = build_frontend.name in {"build[uv]", "uv"}
             uv_path = find_uv()
             if use_uv and uv_path is None:
                 msg = "uv not found"
@@ -494,6 +505,17 @@ def build(options: Options, tmp_path: Path) -> None:
                         *extra_flags,
                         env=build_env,
                     )
+                elif build_frontend.name == "uv":
+                    call(
+                        "uv",
+                        "build",
+                        "--python=python",
+                        build_options.package_dir,
+                        "--wheel",
+                        f"--out-dir={built_wheel_dir}",
+                        *extra_flags,
+                        env=build_env,
+                    )
                 else:
                     assert_never(build_frontend)
 
diff --git a/cibuildwheel/platforms/windows.py b/cibuildwheel/platforms/windows.py
index e429015b9..12b95e8c5 100644
--- a/cibuildwheel/platforms/windows.py
+++ b/cibuildwheel/platforms/windows.py
@@ -244,10 +244,10 @@ def setup_python(
         raise ValueError(msg)
     assert base_python.exists()
 
-    if build_frontend == "build[uv]" and not can_use_uv(python_configuration):
+    if build_frontend in {"build[uv]", "uv"} and not can_use_uv(python_configuration):
         build_frontend = "build"
 
-    use_uv = build_frontend == "build[uv]"
+    use_uv = build_frontend in {"build[uv]", "uv"}
     uv_path = find_uv()
 
     log.step("Setting up build environment...")
@@ -357,7 +357,7 @@ def build(options: Options, tmp_path: Path) -> None:
         for config in python_configurations:
             build_options = options.build_options(config.identifier)
             build_frontend = build_options.build_frontend or BuildFrontendConfig("build")
-            use_uv = build_frontend.name == "build[uv]" and can_use_uv(config)
+            use_uv = build_frontend.name in {"build[uv]", "uv"} and can_use_uv(config)
             log.build_start(config.identifier)
 
             identifier_tmp_dir = tmp_path / config.identifier
@@ -440,6 +440,17 @@ def build(options: Options, tmp_path: Path) -> None:
                         *extra_flags,
                         env=build_env,
                     )
+                elif build_frontend.name == "uv":
+                    call(
+                        "uv",
+                        "build",
+                        "--python=python",
+                        build_options.package_dir,
+                        "--wheel",
+                        f"--out-dir={built_wheel_dir}",
+                        *extra_flags,
+                        env=build_env,
+                    )
                 else:
                     assert_never(build_frontend)
 
diff --git a/cibuildwheel/util/packaging.py b/cibuildwheel/util/packaging.py
index f6619dd92..0b7bf11a6 100644
--- a/cibuildwheel/util/packaging.py
+++ b/cibuildwheel/util/packaging.py
@@ -198,6 +198,6 @@ def combine_constraints(
 
     user_constraints = env.get("PIP_CONSTRAINT")
 
-    env["UV_CONSTRAINT"] = env["PIP_CONSTRAINT"] = " ".join(
+    env["UV_BUILD_CONSTRAINT"] = env["UV_CONSTRAINT"] = env["PIP_CONSTRAINT"] = " ".join(
         c for c in [our_constraints, user_constraints] if c
     )
diff --git a/test/conftest.py b/test/conftest.py
index 8c0c9504c..30b442ab4 100644
--- a/test/conftest.py
+++ b/test/conftest.py
@@ -108,11 +108,13 @@ def docker_warmup_fixture(
     return None
 
 
-@pytest.fixture(params=["pip", "build"])
+@pytest.fixture(params=["pip", "build", "uv"])
 def build_frontend_env_nouv(request: pytest.FixtureRequest) -> dict[str, str]:
     frontend = request.param
-    if platform == "pyodide" and frontend == "pip":
-        pytest.skip("Can't use pip as build frontend for pyodide platform")
+    if platform == "pyodide" and frontend in {"pip", "uv"}:
+        pytest.skip("Can't use pip or uv as build frontend for pyodide platform")
+    if frontend == "uv" and find_uv() is None:
+        pytest.skip("Can't find uv")
 
     return {"CIBW_BUILD_FRONTEND": frontend}
 
diff --git a/unit_test/options_test.py b/unit_test/options_test.py
index fbf181754..94f5ccc3a 100644
--- a/unit_test/options_test.py
+++ b/unit_test/options_test.py
@@ -321,6 +321,11 @@ def test_environment_pass_references():
             "build",
             [],
         ),
+        (
+            'build-frontend = "uv"',
+            "uv",
+            [],
+        ),
         (
             'build-frontend = {name = "build"}',
             "build",