diff --git a/Makefile.am b/Makefile.am
index 734b6f3597..92e6171175 100644
--- a/Makefile.am
+++ b/Makefile.am
@@ -158,6 +158,7 @@ TESTS+=test/test-cases/regression/issue-2099.json
 TESTS+=test/test-cases/regression/issue-2000.json
 TESTS+=test/test-cases/regression/issue-2111.json
 TESTS+=test/test-cases/regression/issue-2196.json
+TESTS+=test/test-cases/regression/issue-2296.json
 TESTS+=test/test-cases/regression/issue-394.json
 TESTS+=test/test-cases/regression/issue-849.json
 TESTS+=test/test-cases/regression/issue-960.json
diff --git a/src/collection/backend/in_memory-per_process.cc b/src/collection/backend/in_memory-per_process.cc
index 717f998216..630b3fd213 100644
--- a/src/collection/backend/in_memory-per_process.cc
+++ b/src/collection/backend/in_memory-per_process.cc
@@ -134,7 +134,7 @@ void InMemoryPerProcess::resolveRegularExpression(const std::string& var,
     //std::string name = std::string(var, var.find(":") + 2,
     //    var.size() - var.find(":") - 3);
     //size_t keySize = col.size();
-    Utils::Regex r(var);
+    Utils::Regex r(var, true);
 
     for (const auto& x : *this) {
         //if (x.first.size() <= keySize + 1) {
diff --git a/src/collection/backend/lmdb.cc b/src/collection/backend/lmdb.cc
index 55afb1c548..9ee05a0ed8 100644
--- a/src/collection/backend/lmdb.cc
+++ b/src/collection/backend/lmdb.cc
@@ -537,7 +537,7 @@ void LMDB::resolveRegularExpression(const std::string& var,
     MDB_stat mst;
     MDB_cursor *cursor;
 
-    Utils::Regex r(var);
+    Utils::Regex r(var, true);
 
     rc = mdb_txn_begin(m_env, NULL, 0, &txn);
     lmdb_debug(rc, "txn", "resolveRegularExpression");
diff --git a/src/utils/regex.cc b/src/utils/regex.cc
index be56e378a0..9f5304f1e8 100644
--- a/src/utils/regex.cc
+++ b/src/utils/regex.cc
@@ -38,12 +38,16 @@ namespace modsecurity {
 namespace Utils {
 
 
-Regex::Regex(const std::string& pattern_)
+Regex::Regex(const std::string& pattern_, bool ignoreCase)
     : pattern(pattern_.empty() ? ".*" : pattern_) {
     const char *errptr = NULL;
     int erroffset;
+    int flags = (PCRE_DOTALL|PCRE_MULTILINE);
 
-    m_pc = pcre_compile(pattern.c_str(), PCRE_DOTALL|PCRE_MULTILINE,
+    if (ignoreCase == true) {
+        flags |= PCRE_CASELESS;
+    }
+    m_pc = pcre_compile(pattern.c_str(), flags,
         &errptr, &erroffset, NULL);
 
     m_pce = pcre_study(m_pc, pcre_study_opt, &errptr);
diff --git a/src/utils/regex.h b/src/utils/regex.h
index 7dcc4dbf61..dd47bd7a27 100644
--- a/src/utils/regex.h
+++ b/src/utils/regex.h
@@ -50,7 +50,7 @@ class SMatch {
 
 class Regex {
  public:
-    explicit Regex(const std::string& pattern_);
+    explicit Regex(const std::string& pattern_, bool ignoreCase = false);
     ~Regex();
 
     // m_pc and m_pce can't be easily copied
diff --git a/test/test-cases/regression/issue-2296.json b/test/test-cases/regression/issue-2296.json
new file mode 100644
index 0000000000..6b73a024b6
--- /dev/null
+++ b/test/test-cases/regression/issue-2296.json
@@ -0,0 +1,90 @@
+[
+  {
+    "enabled":1,
+    "version_min":300000,
+    "title":"Check TX variable case sensitivity (1/2)",
+    "url": "https:\/\/github.com\/SpiderLabs\/ModSecurity\/issues\/2296",
+    "gihub_issue": 2296,
+    "client":{
+      "ip":"200.249.12.31",
+      "port":123
+    },
+    "server":{
+      "ip":"200.249.12.31",
+      "port":80
+    },
+    "request":{
+      "headers":{
+        "Host":"localhost",
+        "User-Agent":"curl/7.38.0",
+        "name1": "value1"
+      },
+      "uri":"/",
+      "method":"GET"
+    },
+    "response":{
+      "headers":{
+        "Date":"Mon, 13 Jul 2015 20:02:41 GMT",
+        "Last-Modified":"Sun, 26 Oct 2014 22:33:37 GMT",
+        "Content-Type":"text/html"
+      },
+      "body":[
+        "no need."
+      ]
+    },
+    "expected":{
+      "http_code":437,
+      "error_log":"`Within' with parameter `/name1/ /name2/' against variable `TX:header_name_name1'"
+    },
+    "rules":[
+        "SecRuleEngine On",
+        "SecAction \"id:1,phase:1,setvar:'TX.restricted_headers=/name1/ /name2/'\"",
+        "SecRule REQUEST_HEADERS_NAMES \"^.*$\" \"id:2,phase:2,t:none,t:lowercase,setvar:'tx.header_name_%{tx.0}=/%{tx.0}/',deny,status:437,msg:'capture',capture,chain\"",
+        "SecRule TX:/^header_name_/ \"@within %{tx.restricted_headers}\" \"setvar:'tx.matched=1',log\""
+    ]
+  },
+  {
+    "enabled":1,
+    "version_min":300000,
+    "title":"Check TX variable case sensitivity (2/2)",
+    "url": "https:\/\/github.com\/SpiderLabs\/ModSecurity\/issues\/2296",
+    "gihub_issue": 2296,
+    "client":{
+      "ip":"200.249.12.31",
+      "port":123
+    },
+    "server":{
+      "ip":"200.249.12.31",
+      "port":80
+    },
+    "request":{
+      "headers":{
+        "Host":"localhost",
+        "User-Agent":"curl/7.38.0",
+        "name1": "value1"
+      },
+      "uri":"/",
+      "method":"GET"
+    },
+    "response":{
+      "headers":{
+        "Date":"Mon, 13 Jul 2015 20:02:41 GMT",
+        "Last-Modified":"Sun, 26 Oct 2014 22:33:37 GMT",
+        "Content-Type":"text/html"
+      },
+      "body":[
+        "no need."
+      ]
+    },
+    "expected":{
+      "http_code":437,
+      "error_log":"`Within' with parameter `/name1/ /name2/' against variable `TX:header_name_name1'"
+    },
+    "rules":[
+        "SecRuleEngine On",
+        "SecAction \"id:1,phase:1,setvar:'TX.restricted_headers=/name1/ /name2/'\"",
+        "SecRule REQUEST_HEADERS_NAMES \"^.*$\" \"id:2,phase:2,t:none,t:lowercase,setvar:'tx.header_name_%{tx.0}=/%{tx.0}/',deny,status:437,msg:'capture',capture,chain\"",
+        "SecRule TX:/^HEADER_NAME_/ \"@within %{tx.restricted_headers}\" \"setvar:'tx.matched=1',log\""
+    ]
+  }
+]