question about multiplicative weights

[katecycho]

Hello,

I am trying to generate a bias file for FitHiC2 from my .mcool file.
I was wondering how I can extract the multiplicative weights from the cool files? I could only find this clr.matrix(divisive_weights=True)[:] but wasn't sure how to dump the weights. Thank you so much for the help.

[nvictus]

If the weights are divisive (like "KR"), you would simply need to grab them from the bin table and invert them:

multiplicative_weights = 1/clr.bins()["KR"][:]