diff --git a/src/ontology/uberon-edit.obo b/src/ontology/uberon-edit.obo
index 4dfe3a275..5a9665529 100644
--- a/src/ontology/uberon-edit.obo
+++ b/src/ontology/uberon-edit.obo
@@ -1161,7 +1161,7 @@ xref: MA:0002907
 xref: SCTID:258665002
 is_a: UBERON:0001305 ! ovarian follicle
 intersection_of: UBERON:0001305 ! ovarian follicle
-intersection_of: has_component UBERON:0005170 {cardinality="1"} ! granulosa cell layer
+intersection_of: has_component UBERON:0005170 ! granulosa cell layer
 relationship: develops_from UBERON:0003981 ! primordial ovarian follicle
 
 [Term]
@@ -1183,7 +1183,7 @@ xref: FMA:18637
 xref: MA:0002908
 is_a: UBERON:0001305 ! ovarian follicle
 intersection_of: UBERON:0001305 ! ovarian follicle
-intersection_of: has_component UBERON:0005170 {minCardinality="2"} ! granulosa cell layer
+intersection_of: has_component UBERON:0005170 ! granulosa cell layer
 intersection_of: has_potential_to_develop_into UBERON:0000037 ! tertiary ovarian follicle
 relationship: develops_from UBERON:0000035 ! primary ovarian follicle
 property_value: editor_note "consider adopting distinction in MA" xsd:string
@@ -1214,7 +1214,7 @@ xref: SCTID:362261008
 xref: UMLS:C0600225 {source="ncithesaurus:Graafian_Follicle"}
 is_a: UBERON:0001305 ! ovarian follicle
 intersection_of: UBERON:0001305 ! ovarian follicle
-intersection_of: has_component UBERON:0005170 {minCardinality="2"} ! granulosa cell layer
+intersection_of: has_component UBERON:0005170 ! granulosa cell layer
 intersection_of: has_part UBERON:0000039 ! follicular antrum
 relationship: develops_from UBERON:0000036 ! secondary ovarian follicle
 property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/e/e6/Primary_follicle-4.JPG" xsd:anyURI
@@ -1527,7 +1527,7 @@ subset: grouping_class
 subset: uberon_slim
 xref: Wikipedia:Eye#Multiple_lenses
 is_a: UBERON:0000047 ! simple eye
-relationship: has_component UBERON:0005389 {min_cardinality="2"} ! transparent eye structure
+relationship: has_component UBERON:0005389 ! transparent eye structure
 relationship: never_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
 
 [Term]
@@ -3732,8 +3732,8 @@ xref: FMA:68877
 intersection_of: UBERON:0034925 ! anatomical collection
 intersection_of: has_member UBERON:0002167 ! right lung
 intersection_of: has_member UBERON:0002168 ! left lung
-relationship: has_member UBERON:0002167 {cardinality="1"} ! right lung
-relationship: has_member UBERON:0002168 {cardinality="1"} ! left lung
+relationship: has_member UBERON:0002167 ! right lung
+relationship: has_member UBERON:0002168 ! left lung
 relationship: located_in UBERON:0002224 ! thoracic cavity
 relationship: part_of UBERON:0001558 {source="FMA-abduced"} ! lower respiratory tract
 
@@ -22584,7 +22584,7 @@ xref: SCTID:244512000
 xref: UMLS:C1182940 {source="ncithesaurus:Vertebral_Joint"}
 is_a: UBERON:0002216 {source="FMA"} ! symphysis
 intersection_of: UBERON:0000982 ! skeletal joint
-intersection_of: connects UBERON:0001075 {cardinality="2"} ! bony vertebral centrum
+intersection_of: connects UBERON:0001075 ! bony vertebral centrum
 relationship: connects UBERON:0001075 {notes="connects successive pairs of centra"} ! bony vertebral centrum
 relationship: part_of UBERON:0001130 {source="FMA"} ! vertebral column
 property_value: external_ontology_notes "FMA has 'intervertebral joint' as a GAT, and has two distinct classes 'intervertebral symphysis' and 'intervertebral syndesmosis', but note that the latter do not connect the centra" xsd:string {external_ontology="FMA"}
@@ -38162,7 +38162,7 @@ xref: Wikipedia:Interchondral_articulations
 is_a: UBERON:0002001 {source="MA"} ! joint of rib
 is_a: UBERON:0002210 {source="FMA"} ! syndesmosis
 relationship: connects UBERON:0002228 {notes="connects two adjacent ribs"} ! rib
-relationship: connects UBERON:0002228 {cardinality="2"} ! rib
+relationship: connects UBERON:0002228 ! rib
 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/cc/Gray315.png" xsd:anyURI
 property_value: editor_note "Consider creating logical definition after obo2owl cardinality tests" xsd:string
 property_value: external_ontology_notes "FMA has both synovial and syndesmosis subtypes - consider adding separate class for FMA:7955 Synovial interchondral joint" xsd:string {external_ontology="FMA"}
@@ -41443,7 +41443,7 @@ synonym: "set of nares" RELATED [FMA:72005]
 xref: FMA:72005
 xref: Wikipedia:Nares
 intersection_of: UBERON:0034925 ! anatomical collection
-intersection_of: has_member UBERON:0000003 {cardinality="2"} ! naris
+intersection_of: has_member UBERON:0000003 ! naris
 relationship: has_part UBERON:0000003 ! naris
 relationship: never_in_taxon NCBITaxon:7745 {source="http://webs.lander.edu/rsfox/invertebrates/ammocoetes.html"} ! Petromyzontiformes
 relationship: part_of UBERON:0000004 ! nose
@@ -52525,7 +52525,7 @@ xref: SCTID:136854008
 xref: Wikipedia:Frontal_suture
 is_a: UBERON:0003685 ! cranial suture
 intersection_of: UBERON:0003685 ! cranial suture
-intersection_of: connects UBERON:0000209 {cardinality="2"} ! tetrapod frontal bone
+intersection_of: connects UBERON:0000209 ! tetrapod frontal bone
 relationship: connects UBERON:0000209 {notes="two halves of the frontal bone"} ! tetrapod frontal bone
 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/17/Gray134.png" xsd:anyURI
 property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/d/d1/Frontal_suture.png" xsd:anyURI
@@ -52568,7 +52568,7 @@ xref: SCTID:244511007
 xref: Wikipedia:Sagittal_suture
 is_a: UBERON:0003685 ! cranial suture
 intersection_of: UBERON:0003685 ! cranial suture
-intersection_of: connects UBERON:0000210 {cardinality="2"} ! tetrapod parietal bone
+intersection_of: connects UBERON:0000210 ! tetrapod parietal bone
 relationship: connects UBERON:0000210 {notes="both parietals"} ! tetrapod parietal bone
 relationship: part_of UBERON:0004339 ! vault of skull
 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/24/Kort-lang-skalle.gif" xsd:anyURI
@@ -82036,7 +82036,7 @@ xref: Wikipedia:Foramen
 intersection_of: UBERON:0010000 ! multicellular anatomical structure
 intersection_of: conduit_for UBERON:0000061 ! anatomical structure
 intersection_of: has_part UBERON:0013686 ! anatomical conduit space
-relationship: connects UBERON:0000464 {cardinality="2"} ! anatomical space
+relationship: connects UBERON:0000464 ! anatomical space
 relationship: present_in_taxon NCBITaxon:33090 ! Viridiplantae
 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa
 relationship: present_in_taxon NCBITaxon:4751 ! Fungi
@@ -107785,7 +107785,7 @@ xref: EMAPA:32618
 xref: MA:0003012
 xref: XAO:0004316
 is_a: UBERON:0010858 ! inter limb-segment region
-relationship: connects UBERON:0002544 {cardinality="2"} ! digit
+relationship: connects UBERON:0002544 ! digit
 relationship: part_of UBERON:0002470 ! autopod region
 property_value: external_ontology_notes "MA and EMAPA mapping from TH" xsd:string {external_ontology="MA"}
 
@@ -107802,7 +107802,7 @@ xref: MA:0000627
 xref: VHOG:0000991
 intersection_of: UBERON:0006012 ! interdigital region
 intersection_of: part_of UBERON:0002398 ! manus
-relationship: adjacent_to UBERON:0002389 {cardinality="2"} ! manual digit
+relationship: adjacent_to UBERON:0002389 ! manual digit
 
 [Term]
 id: UBERON:0006014
@@ -107817,7 +107817,7 @@ xref: MA:0000651
 xref: VHOG:0000992
 intersection_of: UBERON:0006012 ! interdigital region
 intersection_of: part_of UBERON:0002387 ! pes
-relationship: adjacent_to UBERON:0001466 {cardinality="2"} ! pedal digit
+relationship: adjacent_to UBERON:0001466 ! pedal digit
 
 [Term]
 id: UBERON:0006015
@@ -111693,7 +111693,7 @@ xref: NCIT:C52851
 xref: UMLS:C1707451 {source="ncithesaurus:Communicating_Artery"}
 is_a: UBERON:0001637 ! artery
 intersection_of: UBERON:0001637 ! artery
-intersection_of: connects UBERON:0001637 {cardinality="2"} ! artery
+intersection_of: connects UBERON:0001637 ! artery
 
 [Term]
 id: UBERON:0006349
@@ -113855,7 +113855,7 @@ xref: Wikipedia:Symphysis_menti
 xref: ZFA:0005488
 is_a: UBERON:0002216 {source="FMA"} ! symphysis
 intersection_of: UBERON:0002213 ! cartilaginous joint
-intersection_of: connects UBERON:0004742 {cardinality="2"} ! dentary
+intersection_of: connects UBERON:0004742 ! dentary
 relationship: connects UBERON:0004742 {notes="connects adjacent mandibles"} ! dentary
 relationship: part_of UBERON:0001710 ! lower jaw region
 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray176.png" xsd:anyURI
@@ -114567,7 +114567,7 @@ xref: galen:InterphalangealJoint
 xref: NCIT:C101527
 is_a: UBERON:0002217 ! synovial joint
 intersection_of: UBERON:0000982 ! skeletal joint
-intersection_of: connects UBERON:0003221 {cardinality="2"} ! phalanx
+intersection_of: connects UBERON:0003221 ! phalanx
 relationship: connects UBERON:0003221 {notes="two phalanges in series"} ! phalanx
 relationship: part_of UBERON:0002544 {source="cjm"} ! digit
 property_value: external_definition "Hinge joints between the phalanges of the hand or foot[ncithesaurus:Interphalangeal_Joint]." xsd:string {source="ncithesaurus:Interphalangeal_Joint"}
@@ -122414,7 +122414,7 @@ synonym: "junction" BROAD []
 xref: FMA:5898
 xref: SCTID:91833003
 is_a: UBERON:0000061 {source="FMA"} ! anatomical structure
-relationship: connects UBERON:0000061 {minCardinality="2"} ! anatomical structure
+relationship: connects UBERON:0000061 ! anatomical structure
 relationship: present_in_taxon NCBITaxon:33090 ! Viridiplantae
 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa
 relationship: present_in_taxon NCBITaxon:4751 ! Fungi
@@ -122862,7 +122862,7 @@ xref: Wikipedia:Interphalangeal_articulations_of_the_foot
 intersection_of: UBERON:0006658 ! interphalangeal joint
 intersection_of: part_of UBERON:0001466 ! pedal digit
 relationship: connects UBERON:0001449 {notes="two in series"} ! phalanx of pes
-relationship: connects UBERON:0001449 {cardinality="2"} ! phalanx of pes
+relationship: connects UBERON:0001449 ! phalanx of pes
 
 [Term]
 id: UBERON:0007722
@@ -122886,7 +122886,7 @@ xref: Wikipedia:Interphalangeal_articulations_of_the_hand
 intersection_of: UBERON:0006658 ! interphalangeal joint
 intersection_of: part_of UBERON:0002389 ! manual digit
 relationship: connects UBERON:0001436 {notes="two in series"} ! phalanx of manus
-relationship: connects UBERON:0001436 {cardinality="2"} ! phalanx of manus
+relationship: connects UBERON:0001436 ! phalanx of manus
 property_value: editor_note "consider renaming: 'finger' is ambiguous as the term in some usages excludes the thumb (we include it)" xsd:string
 
 [Term]
@@ -122906,7 +122906,7 @@ xref: NCIT:C102306
 xref: SCTID:182192008
 intersection_of: UBERON:0007722 ! interphalangeal joint of manus
 intersection_of: part_of UBERON:0001463 ! manual digit 1
-relationship: connects UBERON:0003620 {cardinality="2"} ! manual digit 1 phalanx
+relationship: connects UBERON:0003620 ! manual digit 1 phalanx
 property_value: taxon_notes "in humans, this connects proximal and distal phalanges of the thumb, so there is only a single inter-phalangeal joint - i.e. there is no distinct proximal and distal joints" xsd:string
 
 [Term]
@@ -122927,7 +122927,7 @@ xref: FMA:35353
 xref: SCTID:363671008
 intersection_of: UBERON:0007721 ! interphalangeal joint of pes
 intersection_of: part_of UBERON:0003631 ! pedal digit 1
-relationship: connects UBERON:0003640 {cardinality="2"} ! pedal digit 1 phalanx
+relationship: connects UBERON:0003640 ! pedal digit 1 phalanx
 
 [Term]
 id: UBERON:0007725
@@ -122940,7 +122940,7 @@ xref: EMAPA:26448
 xref: FMA:35356
 intersection_of: UBERON:0007721 ! interphalangeal joint of pes
 intersection_of: part_of UBERON:0003632 ! pedal digit 2
-relationship: connects UBERON:0003641 {cardinality="2"} ! pedal digit 2 phalanx
+relationship: connects UBERON:0003641 ! pedal digit 2 phalanx
 
 [Term]
 id: UBERON:0007726
@@ -122953,7 +122953,7 @@ xref: EMAPA:26454
 xref: FMA:35359
 intersection_of: UBERON:0007721 ! interphalangeal joint of pes
 intersection_of: part_of UBERON:0003633 ! pedal digit 3
-relationship: connects UBERON:0003642 {cardinality="2"} ! pedal digit 3 phalanx
+relationship: connects UBERON:0003642 ! pedal digit 3 phalanx
 
 [Term]
 id: UBERON:0007727
@@ -122966,7 +122966,7 @@ xref: EMAPA:26466
 xref: FMA:35362
 intersection_of: UBERON:0007721 ! interphalangeal joint of pes
 intersection_of: part_of UBERON:0003634 ! pedal digit 4
-relationship: connects UBERON:0003862 {cardinality="2"} ! pedal digit 4 phalanx
+relationship: connects UBERON:0003862 ! pedal digit 4 phalanx
 
 [Term]
 id: UBERON:0007728
@@ -122980,7 +122980,7 @@ xref: EMAPA:26478
 xref: FMA:35365
 intersection_of: UBERON:0007721 ! interphalangeal joint of pes
 intersection_of: part_of UBERON:0003635 ! pedal digit 5
-relationship: connects UBERON:0003863 {cardinality="2"} ! pedal digit 5 phalanx
+relationship: connects UBERON:0003863 ! pedal digit 5 phalanx
 
 [Term]
 id: UBERON:0007729
@@ -122994,7 +122994,7 @@ xref: EMAPA:25061
 xref: FMA:35397
 intersection_of: UBERON:0007722 ! interphalangeal joint of manus
 intersection_of: part_of UBERON:0003622 ! manual digit 2
-relationship: connects UBERON:0003641 {cardinality="2"} ! pedal digit 2 phalanx
+relationship: connects UBERON:0003641 ! pedal digit 2 phalanx
 relationship: part_of UBERON:0003622 {source="EMAPA"} ! manual digit 2
 
 [Term]
@@ -123009,7 +123009,7 @@ xref: EMAPA:25064
 xref: FMA:35400
 intersection_of: UBERON:0007722 ! interphalangeal joint of manus
 intersection_of: part_of UBERON:0003623 ! manual digit 3
-relationship: connects UBERON:0003642 {cardinality="2"} ! pedal digit 3 phalanx
+relationship: connects UBERON:0003642 ! pedal digit 3 phalanx
 
 [Term]
 id: UBERON:0007731
@@ -123023,7 +123023,7 @@ xref: EMAPA:25067
 xref: FMA:35403
 intersection_of: UBERON:0007722 ! interphalangeal joint of manus
 intersection_of: part_of UBERON:0003624 ! manual digit 4
-relationship: connects UBERON:0003862 {cardinality="2"} ! pedal digit 4 phalanx
+relationship: connects UBERON:0003862 ! pedal digit 4 phalanx
 
 [Term]
 id: UBERON:0007732
@@ -123037,7 +123037,7 @@ xref: EMAPA:25070
 xref: FMA:35407
 intersection_of: UBERON:0007722 ! interphalangeal joint of manus
 intersection_of: part_of UBERON:0003625 ! manual digit 5
-relationship: connects UBERON:0003863 {cardinality="2"} ! pedal digit 5 phalanx
+relationship: connects UBERON:0003863 ! pedal digit 5 phalanx
 
 [Term]
 id: UBERON:0007735
@@ -125812,7 +125812,7 @@ xref: UMLS:C1527245 {source="ncithesaurus:Tarsal_Joint"}
 xref: Wikipedia:Intertarsal_articulations
 is_a: UBERON:0002217 {source="FMA"} ! synovial joint
 intersection_of: UBERON:0000982 ! skeletal joint
-intersection_of: connects UBERON:0001447 {cardinality="2"} ! tarsal bone
+intersection_of: connects UBERON:0001447 ! tarsal bone
 relationship: connects UBERON:0001447 {notes="two adjacent tarsals"} ! tarsal bone
 relationship: part_of UBERON:0004454 ! tarsal region
 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray360.png" xsd:anyURI
@@ -129400,7 +129400,7 @@ xref: SCTID:181772008
 xref: UMLS:C0015641 {source="ncithesaurus:Fascia"}
 xref: Wikipedia:Fascia
 is_a: UBERON:0007846 {source="Wikipedia"} ! dense regular connective tissue
-relationship: connects UBERON:0001630 {cardinality="2"} ! muscle organ
+relationship: connects UBERON:0001630 ! muscle organ
 relationship: connects UBERON:0001630 {notes="fasciae connect muscles to other muscles"} ! muscle organ
 relationship: part_of UBERON:0002204 ! musculoskeletal system
 
@@ -130781,7 +130781,7 @@ def: "Any suture between cranial and/or facial bones." [GO:0097094]
 synonym: "articulation of skull bones" RELATED [OBOL:automatic]
 synonym: "joint of the skull bones" EXACT [OBOL:automatic]
 intersection_of: UBERON:0002209 ! fibrous joint
-intersection_of: connects UBERON:0003457 {minCardinality="2"} ! head bone
+intersection_of: connects UBERON:0003457 ! head bone
 relationship: part_of UBERON:0010323 ! cranial skeletal system
 property_value: editor_note "we follow GO in dividing sutures into cranial and facial and making a grouping class, but this is not consistent with FMA" xsd:string
 
@@ -130791,7 +130791,7 @@ name: facial suture
 def: "Any suture between facial bones." [GO:0097096]
 is_a: UBERON:0009198 ! craniofacial suture
 intersection_of: UBERON:0009198 ! craniofacial suture
-intersection_of: connects UBERON:0003462 {minCardinality="2"} ! facial bone
+intersection_of: connects UBERON:0003462 ! facial bone
 relationship: connects UBERON:0003462 {notes="between two adjacent facial bones"} ! facial bone
 relationship: part_of UBERON:0011156 ! facial skeleton
 
@@ -130837,9 +130837,6 @@ xref: FMA:52959
 xref: SCTID:368990004
 xref: Wikipedia:Internasal_suture
 is_a: UBERON:0011160 ! nasal suture
-intersection_of: UBERON:0009199 ! facial suture
-intersection_of: connects UBERON:0001681 {cardinality="2"} ! nasal bone
-relationship: connects UBERON:0001681 {notes="between both nasal bones"} ! nasal bone
 
 [Term]
 id: UBERON:0009204
@@ -141669,7 +141666,7 @@ name: inter limb-segment region
 comment: Examples - region between digits in a human embryo; segments of a bat's patagium
 synonym: "interlimb" RELATED []
 is_a: UBERON:0034929 ! external soft tissue zone
-relationship: connects UBERON:0002529 {cardinality="2"} ! limb segment
+relationship: connects UBERON:0002529 ! limb segment
 
 [Term]
 id: UBERON:0010861
@@ -143620,7 +143617,7 @@ xref: SCTID:303065007
 xref: Wikipedia:Intermetacarpal_articulations
 is_a: UBERON:0002217 {source="FMA"} ! synovial joint
 intersection_of: UBERON:0000982 ! skeletal joint
-intersection_of: connects UBERON:0002374 {cardinality="2"} ! metacarpal bone
+intersection_of: connects UBERON:0002374 ! metacarpal bone
 relationship: connects UBERON:0002374 {notes="two adjacent metacarpals"} ! metacarpal bone
 relationship: part_of UBERON:0004453 ! metacarpus region
 
@@ -143639,7 +143636,7 @@ xref: UMLS:C1262468 {source="ncithesaurus:Carpal_Joint"}
 xref: Wikipedia:Intercarpal_articulations
 is_a: UBERON:0002217 {source="FMA"} ! synovial joint
 intersection_of: UBERON:0000982 ! skeletal joint
-intersection_of: connects UBERON:0001435 {cardinality="2"} ! carpal bone
+intersection_of: connects UBERON:0001435 ! carpal bone
 relationship: connects UBERON:0001435 {notes="two adjacent carpals"} ! carpal bone
 relationship: part_of UBERON:0004452 {source="FMA"} ! carpal region
 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/37/Gray336.png" xsd:anyURI
@@ -143653,7 +143650,7 @@ xref: SCTID:361868009
 xref: Wikipedia:Intermetatarsal_articulations
 is_a: UBERON:0002217 {source="FMA"} ! synovial joint
 intersection_of: UBERON:0000982 ! skeletal joint
-intersection_of: connects UBERON:0001448 {cardinality="2"} ! metatarsal bone
+intersection_of: connects UBERON:0001448 ! metatarsal bone
 relationship: connects UBERON:0001448 {notes="two adjacent metatarsals"} ! metatarsal bone
 relationship: part_of UBERON:0000983 ! metatarsus region
 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/dc/Gray358.png" xsd:anyURI
@@ -143674,7 +143671,7 @@ def: "A cartilage element that lies between two successive vertebral centra." [I
 xref: AAO:0000795
 is_a: UBERON:0007844 ! cartilage element
 intersection_of: UBERON:0007844 ! cartilage element
-intersection_of: adjacent_to UBERON:0001075 {cardinality="2"} ! bony vertebral centrum
+intersection_of: adjacent_to UBERON:0001075 ! bony vertebral centrum
 relationship: adjacent_to UBERON:0001075 {notes="between two centra"} ! bony vertebral centrum
 relationship: part_of UBERON:0001468 {source="FMA", source="MA"} ! intervertebral joint
 property_value: external_definition "Block of cartilage, which usually ossifies, that lies between successive vertebral centra.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000795", ontology="AAO", source="AAO:Trueb_1973"}
@@ -150412,7 +150409,6 @@ xref: SCTID:410003009
 xref: Wikipedia:Diastema_(dentistry)
 is_a: UBERON:0000464 ! anatomical space
 relationship: adjacent_to UBERON:0001091 ! calcareous tooth
-relationship: adjacent_to UBERON:0001091 {cardinality="2"} ! calcareous tooth
 relationship: part_of UBERON:0001708 ! jaw skeleton
 relationship: part_of UBERON:0003672 ! dentition
 property_value: taxon_notes "Many species of mammals have diastemata as a normal feature, most commonly between the incisors and molars" xsd:string
@@ -150652,7 +150648,6 @@ synonym: "intercuneiform joints" RELATED [Wikipedia:Intercuneiform_articulations
 xref: FMA:35213
 xref: Wikipedia:Intercuneiform_articulations
 is_a: UBERON:0000982 ! skeletal joint
-relationship: connects UBERON:0010721 {cardinality="2"} ! distal tarsal bone
 relationship: connects UBERON:0010721 ! distal tarsal bone
 property_value: terminology_notes "The term 'cuneocuboid articulation' is sometimes used to describe the joint between the cuboid and lateral cuneiform, but this term isn't recognized by Terminologia Anatomica" xsd:string {source="WP"}
 
@@ -154951,7 +154946,7 @@ def: "A large pendulous organ consisting of two or more mammary glands enclosed
 xref: SCTID:27528008
 xref: Wikipedia:Udder
 is_a: UBERON:0000481 ! multi-tissue structure
-relationship: has_component UBERON:0001911 {minCardinality="2"} ! mammary gland
+relationship: has_component UBERON:0001911 ! mammary gland
 relationship: has_component UBERON:0002030 {cardonality="1"} ! nipple
 relationship: has_part UBERON:0001911 ! mammary gland
 relationship: has_part UBERON:0002030 ! nipple
@@ -154998,7 +154993,6 @@ def: "A hole with that connects the left and right aorta in animals of the order
 xref: Wikipedia:Foramen_of_Panizza
 is_a: UBERON:0000464 ! anatomical space
 relationship: connects UBERON:0000947 ! aorta
-relationship: connects UBERON:0000947 {cardinality="2"} ! aorta
 relationship: in_taxon NCBITaxon:8493 {source="Wikipedia"} ! Crocodylidae
 relationship: part_of UBERON:0000948 ! heart
 relationship: part_of UBERON:0004535 {source="Wikipedia"} ! cardiovascular system
@@ -157747,7 +157741,7 @@ subset: common_anatomy
 synonym: "foramen space" NARROW []
 xref: FMA:9338
 is_a: UBERON:0000464 {source="FMA"} ! anatomical space
-relationship: connects UBERON:0000464 {cardinality="2"} ! anatomical space
+relationship: connects UBERON:0000464 ! anatomical space
 relationship: luminal_space_of UBERON:0004111 ! anatomical conduit
 relationship: present_in_taxon NCBITaxon:33090 ! Viridiplantae
 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa
@@ -162209,7 +162203,7 @@ subset: upper_level
 xref: CARO:0010002
 is_a: UBERON:0000062 ! organ
 relationship: composed_primarily_of UBERON:0010001 ! cell cluster organ
-relationship: has_component UBERON:0010001 {min_cardinality="2"} ! cell cluster organ
+relationship: has_component UBERON:0010001 ! cell cluster organ
 
 [Term]
 id: UBERON:0014733
@@ -166860,7 +166854,7 @@ def: "An anatomical line that connects two successive vertebral pedicles. The le
 synonym: "inter-vertebral-pedicle line" EXACT []
 synonym: "interpedicular distance" RELATED [HP:0008450]
 intersection_of: UBERON:0006800 ! anatomical line
-intersection_of: connects UBERON:0001078 {cardinality="2"} ! pedicle of vertebra
+intersection_of: connects UBERON:0001078 ! pedicle of vertebra
 relationship: connects UBERON:0001078 ! pedicle of vertebra
 relationship: part_of UBERON:0001130 ! vertebral column
 
@@ -167634,7 +167628,7 @@ xref: FMA:52851
 xref: FMA:57136
 xref: SCTID:137561005
 intersection_of: UBERON:0005913 ! zone of bone organ
-intersection_of: connects UBERON:0011576 {cardinality="2"} ! supraorbital ridge
+intersection_of: connects UBERON:0011576 ! supraorbital ridge
 relationship: connects UBERON:0011576 ! supraorbital ridge
 relationship: part_of UBERON:0000209 ! tetrapod frontal bone
 relationship: part_of UBERON:0034766 ! glabella region
@@ -167650,7 +167644,7 @@ synonym: "midpalatal suture of skull" EXACT [FMA:52966]
 xref: FMA:52966
 is_a: UBERON:0035127 ! suture of hard palate
 intersection_of: UBERON:0035127 ! suture of hard palate
-intersection_of: connects UBERON:0001682 {cardinality="2"} ! palatine bone
+intersection_of: connects UBERON:0001682 ! palatine bone
 
 [Term]
 id: UBERON:0016446
@@ -181143,7 +181137,7 @@ synonym: "intermaxillary suture of skull" EXACT [FMA:52963]
 xref: FMA:52963
 is_a: UBERON:0009199 ! facial suture
 intersection_of: UBERON:0003685 ! cranial suture
-intersection_of: connects UBERON:0002397 {cardinality="2"} ! maxilla
+intersection_of: connects UBERON:0002397 ! maxilla
 relationship: part_of UBERON:0001709 ! upper jaw region
 
 [Term]
@@ -181229,7 +181223,7 @@ subset: common_anatomy
 xref: CARO:0020000
 is_a: UBERON:0000465 {source="CARO"} ! material anatomical entity
 relationship: composed_primarily_of UBERON:0000061 ! anatomical structure
-relationship: has_component UBERON:0000061 {minCardinality="2"} ! anatomical structure
+relationship: has_component UBERON:0000061 ! anatomical structure
 relationship: has_quality PATO:0010001 ! disconnected
 relationship: present_in_taxon NCBITaxon:33090 ! Viridiplantae
 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa
@@ -182566,7 +182560,7 @@ synonym: "scrotal sac" EXACT [FMA:18251]
 synonym: "testis comartment" EXACT []
 xref: FMA:18251
 is_a: UBERON:0000063 ! organ subunit
-relationship: has_component UBERON:0000473 {cardinality="1"} ! testis
+relationship: has_component UBERON:0000473 ! testis
 relationship: part_of UBERON:0001300 ! scrotum
 
 [Term]
@@ -182673,7 +182667,7 @@ synonym: "interdental space, central incisors" EXACT []
 synonym: "midline diastema" EXACT []
 is_a: UBERON:0012111 ! diastema
 intersection_of: UBERON:0035119 ! diastema between incisors
-intersection_of: adjacent_to UBERON:0018551 {cardinality="2"} ! incisor tooth 1
+intersection_of: adjacent_to UBERON:0018551 ! incisor tooth 1
 relationship: intersects_midsagittal_plane_of UBERON:0001708 ! jaw skeleton
 
 [Term]
@@ -182685,7 +182679,7 @@ synonym: "interdental space, upper central incisors" EXACT []
 synonym: "midline maxillary diastema" EXACT []
 intersection_of: UBERON:0035115 ! diastema between central incisors
 intersection_of: part_of UBERON:0001709 ! upper jaw region
-relationship: adjacent_to UBERON:0018603 {cardinality="2"} ! upper central incisor tooth
+relationship: adjacent_to UBERON:0018603 ! upper central incisor tooth
 relationship: intersects_midsagittal_plane_of UBERON:0003277 ! skeleton of upper jaw
 
 [Term]
@@ -182697,7 +182691,7 @@ synonym: "interdental space, lower central incisors" EXACT []
 synonym: "midline mandibular diastema" EXACT []
 intersection_of: UBERON:0035115 ! diastema between central incisors
 intersection_of: part_of UBERON:0001710 ! lower jaw region
-relationship: adjacent_to UBERON:0018601 {cardinality="2"} ! lower central incisor tooth
+relationship: adjacent_to UBERON:0018601 ! lower central incisor tooth
 relationship: intersects_midsagittal_plane_of UBERON:0003278 ! skeleton of lower jaw
 
 [Term]
@@ -182718,7 +182712,7 @@ synonym: "incisor diastema" EXACT []
 synonym: "interdental space, incisors" EXACT []
 is_a: UBERON:0012111 ! diastema
 intersection_of: UBERON:0012111 ! diastema
-intersection_of: adjacent_to UBERON:0001098 {cardinality="2"} ! incisor tooth
+intersection_of: adjacent_to UBERON:0001098 ! incisor tooth
 relationship: intersects_midsagittal_plane_of UBERON:0001708 ! jaw skeleton
 
 [Term]
@@ -187060,8 +187054,8 @@ synonym: "crena interglutealis" EXACT OMO:0003011 [FMA:TA]
 synonym: "intergluteal crease" EXACT [FMA:20234]
 synonym: "natal cleft" EXACT [FMA:20234]
 xref: FMA:20234
-intersection_of: UBERON:0006800 {exactly="2"} ! anatomical line
-intersection_of: adjacent_to UBERON:0013691 {exactly="2"} ! buttock
+intersection_of: UBERON:0006800 ! anatomical line
+intersection_of: adjacent_to UBERON:0013691 ! buttock
 relationship: adjacent_to UBERON:0013691 ! buttock
 relationship: part_of UBERON:0001137 ! dorsum
 relationship: part_of UBERON:0002355 ! pelvic region of trunk
@@ -187733,7 +187727,7 @@ name: interdigital space
 def: "The space between the digits of the hand or foot." [NCIT:C106201]
 xref: NCIT:C106201
 is_a: UBERON:0000464 ! anatomical space
-relationship: adjacent_to UBERON:0002544 {cardinality="2"} ! digit
+relationship: adjacent_to UBERON:0002544 ! digit
 
 [Term]
 id: UBERON:0036253
diff --git a/src/scripts/relax-cardinality-restrictions.pl b/src/scripts/relax-cardinality-restrictions.pl
new file mode 100755
index 000000000..4d0b841d5
--- /dev/null
+++ b/src/scripts/relax-cardinality-restrictions.pl
@@ -0,0 +1,148 @@
+#!/usr/bin/perl
+# Script to relax all cardinality restrictions in OBO format
+# Removes cardinality, minCardinality, min_cardinality, and exactly constraints
+# from relationship statements
+
+use strict;
+use warnings;
+
+sub relax_cardinality_restrictions {
+    my ($input_file, $output_file) = @_;
+    
+    open my $input_fh, '<', $input_file or die "Cannot open $input_file: $!";
+    open my $output_fh, '>', $output_file or die "Cannot open $output_file: $!";
+    
+    my $changes_made = 0;
+    my @removed_restrictions = ();
+    
+    while (my $line = <$input_fh>) {
+        chomp $line;
+        my $original_line = $line;
+        
+        # Handle various cardinality restriction patterns
+        # Pattern 1: min_cardinality="n" (underscore variant) - check this first
+        if ($line =~ s/\s*\{min_cardinality="(\d+)"\}// ||
+            $line =~ s/\s*\{min_cardinality=(\d+)\}// ||
+            $line =~ s/\s*min_cardinality="(\d+)"// ||
+            $line =~ s/\s*min_cardinality=(\d+)//) {
+            
+            my $min_cardinality_value = $1;
+            push @removed_restrictions, {
+                type => 'min_cardinality_underscore',
+                value => $min_cardinality_value,
+                original => $original_line,
+                modified => $line
+            };
+            $changes_made++;
+        }
+        
+        # Pattern 2: minCardinality="n"  
+        elsif ($line =~ s/\s*\{minCardinality="(\d+)"\}// ||
+               $line =~ s/\s*\{minCardinality=(\d+)\}// ||
+               $line =~ s/\s*minCardinality="(\d+)"// ||
+               $line =~ s/\s*minCardinality=(\d+)//) {
+            
+            my $min_cardinality_value = $1;
+            push @removed_restrictions, {
+                type => 'min_cardinality',
+                value => $min_cardinality_value,
+                original => $original_line,
+                modified => $line
+            };
+            $changes_made++;
+        }
+        
+        # Pattern 3: cardinality="n"
+        elsif ($line =~ s/\s*\{cardinality="(\d+)"\}// || 
+            $line =~ s/\s*\{cardinality=(\d+)\}// ||
+            $line =~ s/\s*cardinality="(\d+)"// ||
+            $line =~ s/\s*cardinality=(\d+)//) {
+            
+            my $cardinality_value = $1;
+            push @removed_restrictions, {
+                type => 'exact_cardinality',
+                value => $cardinality_value,
+                original => $original_line,
+                modified => $line
+            };
+            $changes_made++;
+        }
+        
+        # Pattern 4: exactly="n"
+        elsif ($line =~ s/\s*\{exactly="(\d+)"\}// ||
+               $line =~ s/\s*\{exactly=(\d+)\}// ||
+               $line =~ s/\s*exactly="(\d+)"// ||
+               $line =~ s/\s*exactly=(\d+)//) {
+            
+            my $exactly_value = $1;
+            push @removed_restrictions, {
+                type => 'exactly',
+                value => $exactly_value,
+                original => $original_line,
+                modified => $line
+            };
+            $changes_made++;
+        }
+        
+        # Pattern 5: maxCardinality="n" (for completeness, though not found in current data)
+        elsif ($line =~ s/\s*\{maxCardinality="(\d+)"\}// ||
+               $line =~ s/\s*\{maxCardinality=(\d+)\}// ||
+               $line =~ s/\s*maxCardinality="(\d+)"// ||
+               $line =~ s/\s*maxCardinality=(\d+)//) {
+            
+            my $max_cardinality_value = $1;
+            push @removed_restrictions, {
+                type => 'max_cardinality',
+                value => $max_cardinality_value,
+                original => $original_line,
+                modified => $line
+            };
+            $changes_made++;
+        }
+        
+        print $output_fh "$line\n";
+    }
+    
+    close $input_fh;
+    close $output_fh;
+    
+    # Print summary of changes
+    print STDERR "=== CARDINALITY RESTRICTION RELAXATION SUMMARY ===\n";
+    print STDERR "Total restrictions removed: $changes_made\n";
+    
+    if (@removed_restrictions) {
+        print STDERR "\nDetailed changes:\n";
+        
+        my %type_counts = ();
+        for my $restriction (@removed_restrictions) {
+            $type_counts{$restriction->{type}}++;
+            print STDERR "  $restriction->{type} ($restriction->{value}): $restriction->{original}\n";
+            print STDERR "    -> $restriction->{modified}\n\n";
+        }
+        
+        print STDERR "Summary by type:\n";
+        for my $type (sort keys %type_counts) {
+            print STDERR "  $type: $type_counts{$type} restrictions removed\n";
+        }
+    }
+    
+    return $changes_made;
+}
+
+# Main execution
+if (@ARGV != 2) {
+    die "Usage: $0 <input_obo_file> <output_obo_file>\n";
+}
+
+my ($input_file, $output_file) = @ARGV;
+
+print STDERR "Relaxing cardinality restrictions in $input_file -> $output_file\n";
+my $changes = relax_cardinality_restrictions($input_file, $output_file);
+
+if ($changes > 0) {
+    print STDERR "Successfully relaxed $changes cardinality restrictions.\n";
+} else {
+    print STDERR "No cardinality restrictions found to relax.\n";
+}
+
+exit 0;
\ No newline at end of file