diff --git a/src/ontology/uberon-edit.obo b/src/ontology/uberon-edit.obo index bdb0f1896e..7ca0434238 100644 --- a/src/ontology/uberon-edit.obo +++ b/src/ontology/uberon-edit.obo @@ -34823,8 +34823,7 @@ xref: MA:0001862 xref: NCIT:C33797 xref: UMLS:C1179002 {source="ncithesaurus:Tracheal_Epithelium"} xref: VHOG:0001045 -is_a: UBERON:0000485 ! simple columnar epithelium -intersection_of: UBERON:0000483 ! epithelium +intersection_of: UBERON:1100003 ! conducting airway epithelium intersection_of: part_of UBERON:0003126 ! trachea relationship: contributes_to_morphology_of UBERON:0003126 ! trachea relationship: develops_from UBERON:0003258 ! endoderm of foregut @@ -36854,7 +36853,7 @@ intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002187 ! terminal bronchiole relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 ! Aleix Puig-Barbé relationship: has_part CL:0000158 {source="FMA"} ! club cell -relationship: has_part CL:1000271 ! lung ciliated cell +relationship: has_part CL:1000271 ! lung multiciliated epithelial cell property_value: taxon_notes "A pseudostratified epithelium, containing basal cells, stem cells of the airway, submucosal glands and cartilage rings, is limited to the trachea and large lobar airways in the mouse (Morrisey and Hogan, 2010). This more complex epithelium extends to terminal bronchioles in the human[DOI:10.1242/dev.115469]" xsd:string [Term] @@ -38967,8 +38966,7 @@ xref: FMA:67782 xref: MA:0001839 xref: NCIT:C32231 xref: UMLS:C0599333 {source="ncithesaurus:Bronchial_Epithelium"} -is_a: UBERON:0000485 ! simple columnar epithelium -intersection_of: UBERON:0000483 ! epithelium +intersection_of: UBERON:1100003 ! conducting airway epithelium intersection_of: part_of UBERON:0002185 ! bronchus relationship: contributes_to_morphology_of UBERON:0002185 ! bronchus relationship: has_part CL:0002209 {source="FMA"} ! intermediate epitheliocyte @@ -39642,8 +39640,8 @@ intersection_of: part_of UBERON:0002186 ! bronchiole relationship: contributes_to_morphology_of UBERON:0002186 ! bronchiole relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 ! Aleix Puig-Barbé relationship: has_part CL:0000158 ! club cell -relationship: has_part CL:0002145 {source="FMA"} ! ciliated columnar cell of tracheobronchial tree -relationship: has_part CL:1000271 ! lung ciliated cell +relationship: has_part CL:0002145 {source="FMA"} ! multiciliated columnar cell of tracheobronchial tree +relationship: has_part CL:1000271 ! lung multiciliated epithelial cell relationship: part_of UBERON:0005039 ! mucosa of bronchiole [Term] @@ -47862,11 +47860,11 @@ synonym: "secondary bronchus epithelium" EXACT [OBOL:automatic] xref: EMAPA:32695 xref: FMA:86624 xref: MA:0001842 -intersection_of: UBERON:0000483 ! epithelium +intersection_of: UBERON:1100003 ! conducting airway epithelium intersection_of: part_of UBERON:0002183 ! lobar bronchus relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 ! Aleix Puig-Barbé relationship: has_part CL:0002329 ! basal epithelial cell of tracheobronchial tree -relationship: has_part CL:0002332 ! ciliated cell of the bronchus +relationship: has_part CL:0002332 ! multiciliated epithelial cell of the bronchus relationship: has_part CL:0017000 ! pulmonary ionocyte [Term] @@ -47897,7 +47895,7 @@ xref: FMA:86625 xref: MA:0001847 xref: VHOG:0001034 is_a: UBERON:0002031 ! epithelium of bronchus -intersection_of: UBERON:0000483 ! epithelium +intersection_of: UBERON:1100003 ! conducting airway epithelium intersection_of: part_of UBERON:0002182 ! main bronchus relationship: part_of UBERON:0002182 ! main bronchus @@ -47917,16 +47915,16 @@ xref: EMAPA:37740 {source="MA:th"} xref: FMA:86626 xref: MA:0001850 is_a: UBERON:0002031 ! epithelium of bronchus -intersection_of: UBERON:0000483 ! epithelium +intersection_of: UBERON:1100003 ! conducting airway epithelium intersection_of: part_of UBERON:0002184 ! segmental bronchus relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 ! Aleix Puig-Barbé relationship: has_part CL:0000158 ! club cell relationship: has_part CL:0002208 ! brush cell of bronchus relationship: has_part CL:0002329 ! basal epithelial cell of tracheobronchial tree -relationship: has_part CL:0002332 ! ciliated cell of the bronchus +relationship: has_part CL:0002332 ! multiciliated epithelial cell of the bronchus relationship: has_part CL:0017000 ! pulmonary ionocyte relationship: has_part CL:1000143 ! lung goblet cell -relationship: has_part CL:1000223 ! lung neuroendocrine cell +relationship: has_part CL:1000223 ! pulmonary neuroendocrine cell relationship: part_of UBERON:0002184 ! segmental bronchus [Term] @@ -72967,8 +72965,8 @@ id: UBERON:0003532 name: hindlimb skin def: "A zone of skin that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb skin" EXACT [OBOL:automatic] -synonym: "lower limb skin" EXACT [FMA:23102] synonym: "lower limb skin" EXACT [https://orcid.org/0000-0002-0819-0473] +synonym: "lower limb skin" EXACT [FMA:23102] synonym: "skin of hind limb" EXACT [OBOL:automatic] synonym: "skin of hindlimb" EXACT [OBOL:automatic] synonym: "skin of lower extremity" EXACT [OBOL:automatic] @@ -92458,8 +92456,7 @@ property_value: structure_notes "The epithelium of the cervix is varied. The ect [Term] id: UBERON:0004802 name: respiratory tract epithelium -def: "The pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi." [ISBN:0-683-40008-8, MGI:anna, MP:0010942] -subset: pheno_slim +def: "An epithelium that is part of the respiratory tract." [ISBN:0-683-40008-8] synonym: "airway epithelium" RELATED [BTO:0000419] synonym: "epithelial tissue of respiratory tract" EXACT [OBOL:automatic] synonym: "epithelium of respiratory tract" EXACT [OBOL:automatic] @@ -92467,10 +92464,7 @@ synonym: "respiratory epithelium" RELATED [BTO:0000419] synonym: "respiratory tract epithelial tissue" EXACT [OBOL:automatic] xref: BTO:0000419 xref: CALOHA:TS-0023 -xref: EMAPA:32827 -xref: MA:0001480 xref: SCTID:321764001 -is_a: UBERON:0010499 ! pseudostratified ciliated columnar epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000065 ! respiratory tract relationship: contributes_to_morphology_of UBERON:0001004 ! respiratory system @@ -116141,7 +116135,7 @@ xref: NCIT:C45715 xref: UMLS:C0682578 {source="ncithesaurus:Glandular_Epithelium"} xref: UMLS:C1708242 {source="ncithesaurus:Glandular_Epithelial_Tissue"} intersection_of: UBERON:0000483 ! epithelium -intersection_of: composed_primarily_of CL:0000150 ! glandular epithelial cell +intersection_of: composed_primarily_of CL:0000150 ! glandular secretory epithelial cell disjoint_from: UBERON:0011952 ! non-glandular epithelium property_value: editor_note "consider splitting epithelium from epithelial tissue" xsd:string @@ -117484,14 +117478,14 @@ xref: FMA:64800 xref: NCIT:C13182 xref: UMLS:C0225337 {source="ncithesaurus:Columnar_Epithelium"} intersection_of: UBERON:0000485 ! simple columnar epithelium -intersection_of: composed_primarily_of CL:0000150 ! glandular epithelial cell +intersection_of: composed_primarily_of CL:0000150 ! glandular secretory epithelial cell [Term] id: UBERON:0006930 name: glandular cuboidal epithelium xref: FMA:66809 intersection_of: UBERON:0000484 ! simple cuboidal epithelium -intersection_of: composed_primarily_of CL:0000150 ! glandular epithelial cell +intersection_of: composed_primarily_of CL:0000150 ! glandular secretory epithelial cell [Term] id: UBERON:0006931 @@ -134919,7 +134913,7 @@ synonym: "pulmonary neuroepithelial body" EXACT [MP:0010921] xref: EMAPA:37943 {source="MA:th"} is_a: UBERON:0000061 {source="MP"} ! anatomical structure relationship: contributes_to_morphology_of UBERON:0000115 ! lung epithelium -relationship: has_part CL:1000223 ! lung neuroendocrine cell +relationship: has_part CL:1000223 ! pulmonary neuroendocrine cell relationship: part_of UBERON:0000115 ! lung epithelium relationship: part_of UBERON:8600018 ! neuroendocrine system @@ -166343,7 +166337,7 @@ name: left lung lobar bronchus epithelium def: "An epithelium that is part of a lobar bronchus of left lung." [OBOL:automatic] xref: EMAPA:17658 xref: MA:0003135 -intersection_of: UBERON:0000483 ! epithelium +intersection_of: UBERON:1100003 ! conducting airway epithelium intersection_of: part_of UBERON:0003405 ! lobar bronchus of left lung [Term] @@ -166352,7 +166346,7 @@ name: right lung lobar bronchus epitheium def: "An epithelium that is part of a lobar bronchus of right lung." [OBOL:automatic] xref: EMAPA:17666 xref: MA:0003136 -intersection_of: UBERON:0000483 ! epithelium +intersection_of: UBERON:1100003 ! conducting airway epithelium intersection_of: part_of UBERON:0003404 ! lobar bronchus of right lung [Term] @@ -189986,6 +189980,28 @@ intersection_of: connects UBERON:0004921 ! subdivision of digestive tract relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 ! David Osumi-Sutherland creation_date: 2021-02-05T11:19:31Z +[Term] +id: UBERON:1100003 +name: conducting airway epithelium +def: "The pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi." [ISBN:0-683-40008-8, MGI:anna, MP:0010942] +synonym: "airway epithelium" RELATED [BTO:0000419] +xref: CALOHA:TS-0023 +xref: EMAPA:32827 +xref: MA:0001480 +xref: SCTID:321764001 +intersection_of: UBERON:0010499 ! pseudostratified ciliated columnar epithelium +intersection_of: part_of UBERON:0000065 ! respiratory tract +relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 ! David Osumi-Sutherland +property_value: dcterms-date "2025-03-17T12:43:44Z" xsd:dateTime + +[Term] +id: UBERON:1100004 +name: pseudostratified ciliated epithelium of larynx +intersection_of: UBERON:0010499 ! pseudostratified ciliated columnar epithelium +intersection_of: part_of UBERON:0001737 ! larynx +relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 ! David Osumi-Sutherland +property_value: dcterms-date "2025-03-17T12:59:29Z" xsd:dateTime + [Term] id: UBERON:1500000 name: scapular blade @@ -223958,7 +223974,7 @@ name: epithelium of lobular bronchiole def: "An epithelium of the lobular bronchiole." [FMA:62497] synonym: "epithelium of preterminal bronchiole" EXACT [PMID:16543587] synonym: "lobular bronchiole epithelium" EXACT [FMA:62497] -intersection_of: UBERON:0000483 ! epithelium +intersection_of: UBERON:1100003 ! conducting airway epithelium intersection_of: part_of UBERON:8600000 ! lobular bronchiole relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 ! Aleix Puig-Barbé property_value: dcterms-date "2023-02-10T14:26:09Z" xsd:dateTime