Horse GI tract, ventral colon AND dorsal colon: important for horse transcriptomics

[ANiknejad]

Hello Uberon Team,

The horse colon contains 4 distinct parts, not available so far in UBERON, could be applied to all Equidae, I guess (not found literature so far, will try):

• right ventral
• left ventral
• right dorsal
• left dorsal

https://ohioline.osu.edu/factsheet/1022

Note that the 'pelvic flexure' such as described for horse is also not available in UBERON: "The large colon doubles back on itself and becomes narrower—from 8 inches (20 cm) in diameter to 3–4 inches (9 cm) in diameter—between the ventral and dorsal sections. This location is known as the pelvic flexure (Figure 9).", but UBERON:0022275 colic flexure exists, with a larger definition ("A sharp bend between consecutive segments of the colon.")

I wondering if at least UBERON classes related to ventral colon and dorsal colon could be created, because some transcriptomics studies support a dedicated function for each one:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11350661/#sec5-animals-14-02303

"The differences in gene expression between the ventral and dorsal colons in the equine hindgut relate to tissue function and could impact microbial composition."

Note that the 'pelvic flexure' such as described for horse is also not available in UBERON: "The large colon doubles back on itself and becomes narrower—from 8 inches (20 cm) in diameter to 3–4 inches (9 cm) in diameter—between the ventral and dorsal sections. This location is known as the pelvic flexure (Figure 9). "

• ventral colon
  relationship: part_of UBERON:0001156 ! ascending colon
  def: "One of the U shaped loops of the large colon. The ventral colon has four bands, of which the two ventral ones are free, and the two dorsal ones are associated with the mesentery. The medial dorsal band is associated with the colonic vasculature; In the ventral colon, the site of bacterial fermentation, the teniae have a greater proportion of elastin than in the dorsal colon." [ISBN:9781416001232]
  relationship: present_in_taxon NCBITaxon:9788 ! Equidae

• dorsal colon
  relationship: part_of UBERON:0001156 ! ascending colon
  relationship: present_in_taxon NCBITaxon:9788 ! Equidae

Definition (free text, please give PubMed ID)

https://www.sciencedirect.com/topics/veterinary-science-and-veterinary-medicine/ascending-colon

https://vanat.ahc.umn.edu/ungDissect/Lab13/Lab13.html

https://www.sciencedirect.com/science/article/pii/S0737080621002318

https://pmc.ncbi.nlm.nih.gov/articles/PMC11350661/

Parent term (use https://www.ebi.ac.uk/ols/ontologies/uberon)

Your nano-attribution (ORCID)

[github-actions]

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