diff --git a/.github/workflows/vcpkg_ci_linux.yml b/.github/workflows/vcpkg_ci_linux.yml
index 2f389746..dffaa687 100644
--- a/.github/workflows/vcpkg_ci_linux.yml
+++ b/.github/workflows/vcpkg_ci_linux.yml
@@ -274,51 +274,6 @@ jobs:
           cmake --build . --target install
           ./install/bin/anvill-decompile-json-* -spec ../tools/decompile-json/tests/specs/ret0.json -bc_out ./ret0.bc -ir_out ret0.ir
 
-      - name: 'Anvill-McSema build - custom remill'
-        shell: 'bash'
-        if: ${{ matrix.llvm != 'llvm-12' && matrix.llvm != 'llvm-13' }}
-        run: |
-          cd anvill-mcsema
-          rm -rf build
-          mkdir -p build && cd build
-          cmake -G Ninja \
-            -DCMAKE_VERBOSE_MAKEFILE=ON \
-            -DCMAKE_INSTALL_PREFIX="$(pwd)/install" \
-            -DVCPKG_ROOT="${VCPKG_ROOT}" \
-            -DANVILL_ENABLE_INSTALL_TARGET=ON \
-            -Dremill_DIR="$(pwd)/../../remill/build/install/lib/cmake/remill" \
-            ..
-          cmake --build .
-          cmake --build . --target install
-          ./install/bin/anvill-decompile-json-* -spec ../tools/decompile-json/tests/specs/ret0.json -bc_out ./ret0.bc -ir_out ret0.ir
-
-      - name: 'Test mcsema build'
-        shell: 'bash'
-        if: ${{ matrix.llvm != 'llvm-12' && matrix.llvm != 'llvm-13' }}
-        run: |
-          cd mcsema
-          rm -rf build
-          mkdir -p build && cd build
-          cmake -G Ninja \
-            -DCMAKE_VERBOSE_MAKEFILE=ON \
-            -DCMAKE_INSTALL_PREFIX="$(pwd)/install" \
-            -DVCPKG_ROOT="${VCPKG_ROOT}" \
-            -Dremill_DIR="$(pwd)/../../remill/build/install/lib/cmake/remill" \
-            -Danvill_DIR="$(pwd)/../../anvill-mcsema/build/install/lib/cmake/anvill" \
-            ..
-          cmake --build .
-          cmake --build . --target install
-
-          ./install/bin/mcsema-lift-* --version
-          ./install/bin/mcsema-lift-* --arch amd64 --os linux --cfg ../tests/test_suite_generator/generated/prebuilt_cfg/amd64/linux/cfg/hello_world --output hello_world.bc
-
-          # See https://github.com/lifting-bits/mcsema/issues/753
-          if [ ${{ matrix.host.arch }} == "arm64" ] ; then
-            ./install/bin/mcsema-lift-* --arch x86 --os linux --cfg ../tests/test_suite_generator/generated/prebuilt_cfg/x86/linux/cfg/hello_world --output hello_world.bc || true
-          else
-            ./install/bin/mcsema-lift-* --arch x86 --os linux --cfg ../tests/test_suite_generator/generated/prebuilt_cfg/x86/linux/cfg/hello_world --output hello_world.bc
-          fi
-
       - name: Publish Release Assets
         if: |
           github.event.release
diff --git a/.github/workflows/vcpkg_ci_mac.yml b/.github/workflows/vcpkg_ci_mac.yml
index 9dc530c6..f75787dd 100644
--- a/.github/workflows/vcpkg_ci_mac.yml
+++ b/.github/workflows/vcpkg_ci_mac.yml
@@ -232,43 +232,6 @@ jobs:
           cmake --build . --target install
           ./install/bin/anvill-decompile-json-* -spec ../tools/decompile-json/tests/specs/ret0.json -bc_out ./ret0.bc -ir_out ret0.ir
 
-      - name: 'Anvill-McSema build - custom remill'
-        shell: 'bash'
-        if: ${{ matrix.llvm != 'llvm-12' && matrix.llvm != 'llvm-13' }}
-        run: |
-          cd anvill-mcsema
-          mkdir -p build && cd build
-          cmake -G Ninja \
-            -DCMAKE_VERBOSE_MAKEFILE=ON \
-            -DCMAKE_INSTALL_PREFIX="$(pwd)/install" \
-            -DVCPKG_ROOT="${VCPKG_ROOT}" \
-            -DANVILL_ENABLE_INSTALL_TARGET=ON \
-            -Dremill_DIR="$(pwd)/../../remill/build/install/lib/cmake/remill" \
-            ..
-          cmake --build .
-          cmake --build . --target install
-          ./install/bin/anvill-decompile-json-* -spec ../tools/decompile-json/tests/specs/ret0.json -bc_out ./ret0.bc -ir_out ret0.ir
-
-      - name: 'Test mcsema build'
-        shell: 'bash'
-        if: ${{ matrix.llvm != 'llvm-12' && matrix.llvm != 'llvm-13' }}
-        run: |
-          cd mcsema
-          mkdir -p build && cd build
-          cmake -G Ninja \
-            -DCMAKE_VERBOSE_MAKEFILE=ON \
-            -DCMAKE_INSTALL_PREFIX="$(pwd)/install" \
-            -DVCPKG_ROOT="${VCPKG_ROOT}" \
-            -Dremill_DIR="$(pwd)/../../remill/build/install/lib/cmake/remill" \
-            -Danvill_DIR="$(pwd)/../../anvill-mcsema/build/install/lib/cmake/anvill" \
-            ..
-          cmake --build .
-          cmake --build . --target install
-
-          ./install/bin/mcsema-lift-* --version
-          ./install/bin/mcsema-lift-* --arch amd64 --os linux --cfg ../tests/test_suite_generator/generated/prebuilt_cfg/amd64/linux/cfg/hello_world --output hello_world.bc
-          ./install/bin/mcsema-lift-* --arch x86 --os linux --cfg ../tests/test_suite_generator/generated/prebuilt_cfg/x86/linux/cfg/hello_world --output hello_world.bc
-
       - name: Publish Release Assets
         if: |
           github.event.release
diff --git a/.github/workflows/vcpkg_ci_windows.yml b/.github/workflows/vcpkg_ci_windows.yml
index 552245bb..5576a49d 100644
--- a/.github/workflows/vcpkg_ci_windows.yml
+++ b/.github/workflows/vcpkg_ci_windows.yml
@@ -232,48 +232,6 @@ jobs:
 
           & ( Get-ChildItem install\bin | Where-Object {$_.name -match "anvill-decompile-json-.*.exe"} ) -spec ..\tools\decompile-json\tests\specs\ret0.json -bc_out ret0.bc -ir_out ret0.ir
 
-      - name: 'Anvill-McSema build - custom remill'
-        if: ${{ matrix.llvm == 'llvm-11' }}
-        run: |
-          cd anvill-mcsema
-          Remove-Item -Recurse -Force -ErrorAction SilentlyContinue .\build
-          New-Item -Path .\build -ItemType Directory
-          cd build
-          cmake -T ClangCl `
-            -DCMAKE_VERBOSE_MAKEFILE=ON `
-            -DCMAKE_INSTALL_PREFIX="$(pwd)\install" `
-            -DVCPKG_ROOT="${env:VCPKG_ROOT}" `
-            -DANVILL_ENABLE_INSTALL_TARGET=ON `
-            -Dremill_DIR="$(pwd)\..\..\remill\build\install\lib\cmake\remill" `
-            ..
-          cmake --build . --config Release -j
-          cmake --build . --config Release --target install
-
-          & ( Get-ChildItem install\bin | Where-Object {$_.name -match "anvill-decompile-json-.*.exe"} ) -spec ..\tools\decompile-json\tests\specs\ret0.json -bc_out ret0.bc -ir_out ret0.ir
-
-      - name: 'Test mcsema build'
-        if: ${{ matrix.llvm == 'llvm-11' }}
-        run: |
-          cd mcsema
-          Remove-Item -Recurse -Force -ErrorAction SilentlyContinue .\build
-          New-Item -Path .\build -ItemType Directory
-          cd build
-          cmake -T ClangCl `
-            -DCMAKE_VERBOSE_MAKEFILE=ON `
-            -DCMAKE_INSTALL_PREFIX="$(pwd)\install" `
-            -DVCPKG_ROOT="${env:VCPKG_ROOT}" `
-            -DMCSEMA_INSTALL_PYTHON2_LIBS=OFF `
-            -DMCSEMA_INSTALL_PYTHON3_LIBS=OFF `
-            -Dremill_DIR="$(pwd)\..\..\remill\build\install\lib\cmake\remill" `
-            -Danvill_DIR="$(pwd)\..\..\anvill-mcsema\build\install\lib\cmake\anvill" `
-            ..
-          cmake --build . --config Release -j
-          cmake --build . --config Release --target install
-
-          & ( Get-ChildItem install\mcsema\bin | Where-Object {$_.name -match "mcsema-lift-.*.exe"} ) --version
-          & ( Get-ChildItem install\mcsema\bin | Where-Object {$_.name -match "mcsema-lift-.*.exe"} ) --arch amd64 --os linux --cfg ..\tests\test_suite_generator\generated\prebuilt_cfg\amd64\linux\cfg\hello_world --output hello_world.bc
-          & ( Get-ChildItem install\mcsema\bin | Where-Object {$_.name -match "mcsema-lift-.*.exe"} ) --arch x86 --os linux --cfg ..\tests\test_suite_generator\generated\prebuilt_cfg\x86\linux\cfg\hello_world --output hello_world.bc
-
       - name: Publish Release Assets
         if: |
           github.event.release
diff --git a/.gitmodules b/.gitmodules
index 4878be08..72843a78 100644
--- a/.gitmodules
+++ b/.gitmodules
@@ -1,7 +1,3 @@
-[submodule "mcsema"]
-	path = mcsema
-	url = https://github.com/lifting-bits/mcsema.git
-	branch = master
 [submodule "remill"]
 	path = remill
 	url = https://github.com/lifting-bits/remill.git
@@ -14,6 +10,3 @@
 	path = rellic
 	url = https://github.com/lifting-bits/rellic.git
 	branch = master
-[submodule "anvill-mcsema"]
-	path = anvill-mcsema
-	url = https://github.com/lifting-bits/anvill.git
diff --git a/anvill-mcsema b/anvill-mcsema
deleted file mode 160000
index bc3183b8..00000000
--- a/anvill-mcsema
+++ /dev/null
@@ -1 +0,0 @@
-Subproject commit bc3183b8a08f12b9c2f9b97af2bcc0f0138dbb7a
diff --git a/mcsema b/mcsema
deleted file mode 160000
index d538ca4a..00000000
--- a/mcsema
+++ /dev/null
@@ -1 +0,0 @@
-Subproject commit d538ca4acc0918894924ab28ce889d14157beb83