diff --git a/src/webgpu/gpu_test.ts b/src/webgpu/gpu_test.ts
index b9ee2b776db5..ed8c170d93d2 100644
--- a/src/webgpu/gpu_test.ts
+++ b/src/webgpu/gpu_test.ts
@@ -300,6 +300,14 @@ export class GPUTestSubcaseBatchState extends SubcaseBatchState {
     }
   }
 
+  /** Skips this test case if a depth texture can not be used with a non-comparison sampler. */
+  skipIfDepthTextureCanNotBeUsedWithNonComparisonSampler() {
+    this.skipIf(
+      this.isCompatibility,
+      'depth textures are not usable with non-comparison samplers in compatibility mode'
+    );
+  }
+
   /** Skips this test case if the `langFeature` is *not* supported. */
   skipIfLanguageFeatureNotSupported(langFeature: WGSLLanguageFeature) {
     if (!this.hasLanguageFeature(langFeature)) {
diff --git a/src/webgpu/shader/execution/expression/call/builtin/textureGather.spec.ts b/src/webgpu/shader/execution/expression/call/builtin/textureGather.spec.ts
index 85ff9027bf88..5aae5bafbe57 100644
--- a/src/webgpu/shader/execution/expression/call/builtin/textureGather.spec.ts
+++ b/src/webgpu/shader/execution/expression/call/builtin/textureGather.spec.ts
@@ -512,7 +512,10 @@ Parameters:
       .beginSubcases()
       .combine('samplePoints', kSamplePointMethods)
   )
-  .beforeAllSubcases(t => t.selectDeviceForTextureFormatOrSkipTestCase(t.params.format))
+  .beforeAllSubcases(t => {
+    t.skipIfDepthTextureCanNotBeUsedWithNonComparisonSampler();
+    t.selectDeviceForTextureFormatOrSkipTestCase(t.params.format);
+  })
   .fn(async t => {
     const { format, stage, samplePoints, modeU, modeV, offset } = t.params;
 
@@ -591,7 +594,10 @@ Parameters:
       .beginSubcases()
       .combine('samplePoints', kCubeSamplePointMethods)
   )
-  .beforeAllSubcases(t => t.selectDeviceForTextureFormatOrSkipTestCase(t.params.format))
+  .beforeAllSubcases(t => {
+    t.skipIfDepthTextureCanNotBeUsedWithNonComparisonSampler();
+    t.selectDeviceForTextureFormatOrSkipTestCase(t.params.format);
+  })
   .fn(async t => {
     const { format, stage, samplePoints, mode } = t.params;
 
@@ -688,6 +694,7 @@ Parameters:
       .combine('A', ['i32', 'u32'] as const)
   )
   .beforeAllSubcases(t => {
+    t.skipIfDepthTextureCanNotBeUsedWithNonComparisonSampler();
     t.skipIfTextureFormatNotSupported(t.params.format);
     t.selectDeviceForTextureFormatOrSkipTestCase(t.params.format);
   })
@@ -779,6 +786,7 @@ Parameters:
       .combine('A', ['i32', 'u32'] as const)
   )
   .beforeAllSubcases(t => {
+    t.skipIfDepthTextureCanNotBeUsedWithNonComparisonSampler();
     t.skipIfTextureViewDimensionNotSupported('cube-array');
     t.selectDeviceForTextureFormatOrSkipTestCase(t.params.format);
   })
diff --git a/src/webgpu/shader/execution/expression/call/builtin/textureSample.spec.ts b/src/webgpu/shader/execution/expression/call/builtin/textureSample.spec.ts
index 1aa84583ee55..386101462eb8 100644
--- a/src/webgpu/shader/execution/expression/call/builtin/textureSample.spec.ts
+++ b/src/webgpu/shader/execution/expression/call/builtin/textureSample.spec.ts
@@ -389,7 +389,10 @@ Parameters:
       .beginSubcases()
       .combine('samplePoints', kSamplePointMethods)
   )
-  .beforeAllSubcases(t => t.selectDeviceForTextureFormatOrSkipTestCase(t.params.format))
+  .beforeAllSubcases(t => {
+    t.skipIfDepthTextureCanNotBeUsedWithNonComparisonSampler();
+    t.selectDeviceForTextureFormatOrSkipTestCase(t.params.format);
+  })
   .fn(async t => {
     const { format, samplePoints, modeU, modeV, offset } = t.params;
 
@@ -680,6 +683,7 @@ Parameters:
       .combine('samplePoints', kCubeSamplePointMethods)
   )
   .beforeAllSubcases(t => {
+    t.skipIfDepthTextureCanNotBeUsedWithNonComparisonSampler();
     t.skipIfTextureViewDimensionNotSupported(t.params.viewDimension);
     t.selectDeviceForTextureFormatOrSkipTestCase(t.params.format);
   })
@@ -786,7 +790,10 @@ Parameters:
       .combine('A', ['i32', 'u32'] as const)
       .combine('L', ['i32', 'u32'] as const)
   )
-  .beforeAllSubcases(t => t.selectDeviceForTextureFormatOrSkipTestCase(t.params.format))
+  .beforeAllSubcases(t => {
+    t.skipIfDepthTextureCanNotBeUsedWithNonComparisonSampler();
+    t.selectDeviceForTextureFormatOrSkipTestCase(t.params.format);
+  })
   .fn(async t => {
     const { format, samplePoints, mode, A, L, offset } = t.params;
 
@@ -874,6 +881,7 @@ Parameters:
       .combine('A', ['i32', 'u32'] as const)
   )
   .beforeAllSubcases(t => {
+    t.skipIfDepthTextureCanNotBeUsedWithNonComparisonSampler();
     t.skipIfTextureViewDimensionNotSupported('cube-array');
     t.selectDeviceForTextureFormatOrSkipTestCase(t.params.format);
   })
diff --git a/src/webgpu/shader/execution/expression/call/builtin/textureSampleLevel.spec.ts b/src/webgpu/shader/execution/expression/call/builtin/textureSampleLevel.spec.ts
index bbc387927f16..78a3c6361379 100644
--- a/src/webgpu/shader/execution/expression/call/builtin/textureSampleLevel.spec.ts
+++ b/src/webgpu/shader/execution/expression/call/builtin/textureSampleLevel.spec.ts
@@ -538,9 +538,10 @@ Parameters:
       .combine('samplePoints', kSamplePointMethods)
       .combine('L', ['i32', 'u32'] as const)
   )
-  .beforeAllSubcases(t =>
-    skipIfTextureFormatNotSupportedNotAvailableOrNotFilterable(t, t.params.format)
-  )
+  .beforeAllSubcases(t => {
+    t.skipIfDepthTextureCanNotBeUsedWithNonComparisonSampler();
+    skipIfTextureFormatNotSupportedNotAvailableOrNotFilterable(t, t.params.format);
+  })
   .fn(async t => {
     const { format, stage, samplePoints, mode, L, offset } = t.params;
 
@@ -640,9 +641,10 @@ Parameters:
       .combine('A', ['i32', 'u32'] as const)
       .combine('L', ['i32', 'u32'] as const)
   )
-  .beforeAllSubcases(t =>
-    skipIfTextureFormatNotSupportedNotAvailableOrNotFilterable(t, t.params.format)
-  )
+  .beforeAllSubcases(t => {
+    t.skipIfDepthTextureCanNotBeUsedWithNonComparisonSampler();
+    skipIfTextureFormatNotSupportedNotAvailableOrNotFilterable(t, t.params.format);
+  })
   .fn(async t => {
     const { format, stage, samplePoints, mode, A, L, offset } = t.params;
 
@@ -749,6 +751,7 @@ Parameters:
       .combine('L', ['i32', 'u32'] as const)
   )
   .beforeAllSubcases(t => {
+    t.skipIfDepthTextureCanNotBeUsedWithNonComparisonSampler();
     skipIfTextureFormatNotSupportedNotAvailableOrNotFilterable(t, t.params.format);
     t.skipIfTextureViewDimensionNotSupported(t.params.viewDimension);
   })