diff --git a/.github/workflows/macos.yml b/.github/workflows/macos.yml
index e9e693e57c3..ac3ed0ad0b1 100644
--- a/.github/workflows/macos.yml
+++ b/.github/workflows/macos.yml
@@ -23,6 +23,7 @@ jobs:
     runs-on: macos-14
     env:
       PYTHONWARNINGS: always
+      ASAN_OPTIONS: detect_leaks=1,detect_odr_violation=1
     steps:
       - name: Info
         run: |
@@ -80,9 +81,34 @@ jobs:
           $CC --version
       - name: Create installation directory
         run: mkdir $HOME/install
+      - name: Show clang path
+        shell: micromamba-shell {0}
+        run: which clang
+      # llvm-symbolizer, if on path or specified with ASAN_SYMBOLIZER_PATH,
+      # enhances tracebacks with line numbers instead of addresses
+      - name: Show llvm-symbolizer
+        shell: micromamba-shell {0}
+        run: which llvm-symbolizer
+      # Commented below are some possible flags to pass to not exit on failures
       - name: Build and install
         shell: micromamba-shell {0}
-        run: source ./.github/workflows/macos_install.sh $HOME/install
+        run: source ./.github/workflows/macos_install.sh $HOME/install $G_CFLAGS_APPEND
+        env:
+          G_CFLAGS_APPEND: >-
+            -g
+            -fcolor-diagnostics
+            -fno-omit-frame-pointer
+            -fsanitize=address
+            -Wno-error=deprecated-declarations
+            -Wdeprecated-declarations
+#            -fsanitize-recover=address
+#            -fsanitize-recover=all
+          G_LDFLAGS_APPEND: >-
+            -fno-omit-frame-pointer
+            -fsanitize=address
+#            -fsanitize-recover=address
+          ASAN_OPTIONS: detect_leaks=0,detect_odr_violation=1
+          DYLD_INSERT_LIBRARIES: /Users/runner/micromamba/envs/grass-env/lib/clang/20/lib/darwin/libclang_rt.asan_osx_dynamic.dylib
       - name: Add the bin directory to PATH
         run: echo "$HOME/install/bin" >> $GITHUB_PATH
       - name: Check installed version
diff --git a/.github/workflows/macos_install.sh b/.github/workflows/macos_install.sh
index 4f340c73f9e..3e66af6c053 100755
--- a/.github/workflows/macos_install.sh
+++ b/.github/workflows/macos_install.sh
@@ -63,10 +63,27 @@ export CFLAGS="-O2 -pipe -ffp-contract=off -arch ${CONDA_ARCH} -DGL_SILENCE_DEPR
 export CXXFLAGS="-O2 -pipe -ffp-contract=off -stdlib=libc++ -arch ${CONDA_ARCH} -Wall -Wextra -Wpedantic"
 export CPPFLAGS="-isystem${CONDA_PREFIX}/include"
 
-./configure $CONFIGURE_FLAGS
+LDFLAGS="$LDFLAGS $G_LDFLAGS_APPEND" ./configure $CONFIGURE_FLAGS
 
 EXEMPT=""
-make -j$(sysctl -n hw.ncpu) CFLAGS="$CFLAGS -Werror $EXEMPT" \
-  CXXFLAGS="$CXXFLAGS -Werror $EXEMPT"
 
+# Adding -Werror to make's CFLAGS is a workaround for configuring with
+# an old version of configure, which issues compiler warnings and
+# errors out. This may be removed with upgraded configure.in file.
+#makecmd="make"
+#makecmd="make -j$(sysctl -n hw.ncpu) CFLAGS='$CFLAGS  -Werror $EXEMPT' CXXFLAGS='$CXXFLAGS -Werror $EXEMPT' LDFLAGS='$LDFLAGS $G_LDFLAGS_APPEND'"
+makecmd="make -j$(sysctl -n hw.ncpu) CFLAGS='$CFLAGS  -Werror $EXEMPT' CXXFLAGS='$CXXFLAGS -Werror $EXEMPT'"
+
+#echo "Running normal make, with flags"
+#make -j$(sysctl -n hw.ncpu) CFLAGS="$CFLAGS  -Werror $EXEMPT" CXXFLAGS="$CXXFLAGS -Werror $EXEMPT"
+
+echo "before extra args"
+if [[ "$#" -ge 2 ]]; then
+    ARGS=("$@")
+    echo "in extra args"
+    makecmd="make -j$(sysctl -n hw.ncpu) CFLAGS='$CFLAGS  -Werror ${ARGS[@]:1} $EXEMPT' CXXFLAGS='$CXXFLAGS -Werror ${ARGS[@]:1} $EXEMPT'"
+fi
+
+echo "The make command is: $makecmd"
+eval $makecmd
 make install
diff --git a/python/libgrass_interface_generator/Makefile b/python/libgrass_interface_generator/Makefile
index c2aa362db56..4db0c00b978 100644
--- a/python/libgrass_interface_generator/Makefile
+++ b/python/libgrass_interface_generator/Makefile
@@ -60,7 +60,7 @@ ifneq ($(MINGW),)
 INTLLIB = -lintl-8
 endif
 
-CTYPESGEN = ./run.py
+CTYPESGEN = DYLD_INSERT_LIBRARIES=/Users/runner/micromamba/envs/grass-env/lib/clang/20/lib/darwin/libclang_rt.asan_osx_dynamic.dylib ./run.py
 CTYPESFLAGS = --no-embed-preamble --strip-build-path "$(ARCH_DISTDIR)" \
 	--cpp "$(CC) -E $(CPPFLAGS) $(LFS_CFLAGS) $(EXTRA_CFLAGS) $(NLS_CFLAGS) $(DEFS) $(EXTRA_INC) $(INC) -D__GLIBC_HAVE_LONG_LONG"
 EXTRA_CLEAN_FILES := $(wildcard ctypesgen/*.pyc) $(wildcard ctypesgen/*/*.pyc)