diff --git a/Source/Core/DolphinQt/EmulatedUSB/WiiSpeakWindow.cpp b/Source/Core/DolphinQt/EmulatedUSB/WiiSpeakWindow.cpp
index 093c08b778b5..11b41fc797a3 100644
--- a/Source/Core/DolphinQt/EmulatedUSB/WiiSpeakWindow.cpp
+++ b/Source/Core/DolphinQt/EmulatedUSB/WiiSpeakWindow.cpp
@@ -7,6 +7,7 @@
 #include <QComboBox>
 #include <QGroupBox>
 #include <QHBoxLayout>
+#include <QLabel>
 #include <QString>
 #include <QVBoxLayout>
 
@@ -38,6 +39,10 @@ WiiSpeakWindow::~WiiSpeakWindow() = default;
 void WiiSpeakWindow::CreateMainWindow()
 {
   auto* main_layout = new QVBoxLayout();
+  auto* label = new QLabel();
+  label->setText(QStringLiteral("<center><i>%1</i></center>")
+                     .arg(tr("Some settings cannot be changed when emulation is running.")));
+  main_layout->addWidget(label);
 
   auto* checkbox_group = new QGroupBox();
   auto* checkbox_layout = new QHBoxLayout();
@@ -74,7 +79,6 @@ void WiiSpeakWindow::CreateMainWindow()
   config_layout->addWidget(m_combobox_microphones);
 
   m_config_group->setLayout(config_layout);
-  m_config_group->setVisible(Config::Get(Config::MAIN_EMULATE_WII_SPEAK));
   main_layout->addWidget(m_config_group);
 
   setLayout(main_layout);