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New benchmark reference geometry stability #664

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@lwehrhan

Summary

This benchmark assesses the MLIP's capability to preserve the ground-state geometry of organic small molecules during energy minimization. It draws its test set from the OpenFF industry dataset, which contains 73,301 conformers of thousands of different molecules, collected by industry partners of the OpenFF consortium. 200 neutral molecules and 20 charged molecules were picked from this dataset, maximizing chemical diversity based on Morgan fingerprints.

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Histogram plot

Category

molecular

Data availability

Selected input structures on MLIP Audit HuggingFace page. Geometries sourced from:

L. D’Amore, […], Gary Tresadern, J. Chem. Inf. Model. 2022. DOI: https://doi.org/10.1021/acs.jcim.2c01185

Computational cost

Medium: 220 short geometry optimizations of organic small molecules

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