When g:tmux_navigator_no_wrap is enabled, #{pane_at_*} variables are used to detect being at the edge of the tmux window and conditionally disable navigation. However, when in zoomed mode, all #{pane_at_*} variables are 1 preventing navigation in all directions.
I think the most correct behavior would be to navigate as if the pane was not zoomed (detect if pane would be the last in a given direction in unzoomed mode), but I don't think it can be implemented in the current version of tmux in a nice way.
As a workaround, it would be good to have an option to disable the wrap check when in zoomed mode, so that navigation outside of vim is possible, albeit wrapped.