diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 9f7008c3c4..cd2d085b72 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -38,6 +38,10 @@ jobs:
       - name: Check
         run: cargo check --workspace --all-targets --all-features
 
+      # Check with musl libc target which is used for `deltachat-rpc-server` releases.
+      - name: Check musl
+        run: scripts/zig-musl-check.sh
+
   cargo_deny:
     name: cargo deny
     runs-on: ubuntu-latest
diff --git a/Cargo.lock b/Cargo.lock
index 15900472ae..634d081f51 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -2661,9 +2661,9 @@ dependencies = [
 
 [[package]]
 name = "libc"
-version = "0.2.145"
+version = "0.2.146"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "fc86cde3ff845662b8f4ef6cb50ea0e20c524eb3d29ae048287e06a1b3fa6a81"
+checksum = "f92be4933c13fd498862a9e02a3055f8a8d9c039ce33db97306fd5a6caa7f29b"
 
 [[package]]
 name = "libm"
diff --git a/scripts/zig-musl-check.sh b/scripts/zig-musl-check.sh
new file mode 100755
index 0000000000..1e4afd6db1
--- /dev/null
+++ b/scripts/zig-musl-check.sh
@@ -0,0 +1,28 @@
+#!/bin/sh
+#
+# Run `cargo check` with musl libc.
+# This requires `zig` to compile vendored openssl.
+
+set -x
+set -e
+
+unset RUSTFLAGS
+
+# Pin Rust version to avoid uncontrolled changes in the compiler and linker flags.
+export RUSTUP_TOOLCHAIN=1.70.0
+
+ZIG_VERSION=0.11.0-dev.2213+515e1c93e
+
+# Download Zig
+rm -fr "$ZIG_VERSION" "zig-linux-x86_64-$ZIG_VERSION.tar.xz"
+wget "https://ziglang.org/builds/zig-linux-x86_64-$ZIG_VERSION.tar.xz"
+tar xf "zig-linux-x86_64-$ZIG_VERSION.tar.xz"
+export PATH="$PWD/zig-linux-x86_64-$ZIG_VERSION:$PATH"
+
+rustup target add x86_64-unknown-linux-musl
+CC="$PWD/scripts/zig-cc" \
+TARGET_CC="$PWD/scripts/zig-cc" \
+CARGO_TARGET_X86_64_UNKNOWN_LINUX_MUSL_LINKER="$PWD/scripts/zig-cc" \
+LD="$PWD/scripts/zig-cc" \
+ZIG_TARGET="x86_64-linux-musl" \
+cargo check --release --target x86_64-unknown-linux-musl -p deltachat_ffi --features jsonrpc
diff --git a/scripts/zig-rpc-server.sh b/scripts/zig-rpc-server.sh
index e411b20bb8..ee96905bb7 100755
--- a/scripts/zig-rpc-server.sh
+++ b/scripts/zig-rpc-server.sh
@@ -8,7 +8,7 @@ set -e
 unset RUSTFLAGS
 
 # Pin Rust version to avoid uncontrolled changes in the compiler and linker flags.
-export RUSTUP_TOOLCHAIN=1.68.1
+export RUSTUP_TOOLCHAIN=1.70.0
 
 ZIG_VERSION=0.11.0-dev.2213+515e1c93e