diff --git a/cmake/BuildParameters.cmake b/cmake/BuildParameters.cmake
index 4987fca42bb49..89ab1db70e9ab 100644
--- a/cmake/BuildParameters.cmake
+++ b/cmake/BuildParameters.cmake
@@ -39,6 +39,11 @@ option(USE_VTUNE "Plug VTUNE to profile GS JIT.")
 #-------------------------------------------------------------------------------
 option(BUILD_REPLAY_LOADERS "Build GS replayer to ease testing (developer option)")
 option(USE_VULKAN "Enable Vulkan GS renderer" ON)
+if (APPLE)
+	option(USE_METAL "Enable Metal GS renderer" ON)
+else()
+	option(USE_METAL "Enable Metal GS renderer" OFF)
+endif()
 
 #-------------------------------------------------------------------------------
 # Path and lib option
@@ -242,6 +247,10 @@ if(USE_VULKAN)
 	list(APPEND PCSX2_DEFS ENABLE_VULKAN)
 endif()
 
+if (USE_METAL)
+	list(APPEND PCSX2_DEFS ENABLE_METAL)
+endif()
+
 if(X11_API)
 	list(APPEND PCSX2_DEFS X11_API)
 endif()
diff --git a/pcsx2/CMakeLists.txt b/pcsx2/CMakeLists.txt
index 564547c7af082..df701a915de44 100644
--- a/pcsx2/CMakeLists.txt
+++ b/pcsx2/CMakeLists.txt
@@ -982,7 +982,7 @@ if(WIN32)
 	list(APPEND pcsx2FrontendHeaders
 		Frontend/D3D11HostDisplay.h
 	)
-elseif(APPLE)
+elseif(USE_METAL)
 	list(APPEND pcsx2GSSources
 		GS/Renderers/Metal/GSDeviceMTL.mm
 		GS/Renderers/Metal/GSMTLDeviceInfo.mm
@@ -1708,6 +1708,7 @@ if(GETTEXT_FOUND AND NOT NO_TRANSLATION AND NOT PCSX2_CORE)
 endif()
 
 if (APPLE)
+	if(USE_METAL)
 	find_library(METAL_LIBRARY Metal)
 	target_link_libraries(PCSX2 PRIVATE ${METAL_LIBRARY})
 
@@ -1750,6 +1751,7 @@ if (APPLE)
 		generateMetallib(macos-metal2.2 air64-apple-macos10.15 Metal22)
 		generateMetallib(macos-metal2.3 air64-apple-macos11.0  Metal23)
 	endif()
+	endif(USE_METAL)
 
 	# MacOS defaults to having a maximum protection of the __DATA segment of rw (non-executable)
 	# We have a bunch of page-sized arrays in bss that we use for jit
diff --git a/pcsx2/GS/GS.cpp b/pcsx2/GS/GS.cpp
index 1c2d9042dd3dc..7130c7dc3870a 100644
--- a/pcsx2/GS/GS.cpp
+++ b/pcsx2/GS/GS.cpp
@@ -164,7 +164,7 @@ static HostDisplay::RenderAPI GetAPIForRenderer(GSRendererType renderer)
 		case GSRendererType::VK:
 			return HostDisplay::RenderAPI::Vulkan;
 
-#ifdef __APPLE__
+#ifdef ENABLE_METAL
 		case GSRendererType::Metal:
 			return HostDisplay::RenderAPI::Metal;
 #endif
@@ -191,7 +191,7 @@ static bool DoGSOpen(GSRendererType renderer, u8* basemem)
 			g_gs_device = std::make_unique<GSDevice11>();
 			break;
 #endif
-#ifdef __APPLE__
+#ifdef ENABLE_METAL
 		case HostDisplay::RenderAPI::Metal:
 			g_gs_device = std::unique_ptr<GSDevice>(MakeGSDeviceMTL());
 			break;
@@ -1199,7 +1199,7 @@ void GSApp::Init()
 #ifdef _WIN32
 	m_gs_renderers.push_back(GSSetting(static_cast<u32>(GSRendererType::DX11), "Direct3D 11", ""));
 #endif
-#ifdef __APPLE__
+#ifdef ENABLE_METAL
 	m_gs_renderers.push_back(GSSetting(static_cast<u32>(GSRendererType::Metal), "Metal", ""));
 #endif
 	m_gs_renderers.push_back(GSSetting(static_cast<u32>(GSRendererType::OGL), "OpenGL", ""));
diff --git a/pcsx2/GS/Renderers/Metal/GSMetalCPPAccessible.h b/pcsx2/GS/Renderers/Metal/GSMetalCPPAccessible.h
index cd4fae81200e3..231da76901734 100644
--- a/pcsx2/GS/Renderers/Metal/GSMetalCPPAccessible.h
+++ b/pcsx2/GS/Renderers/Metal/GSMetalCPPAccessible.h
@@ -16,7 +16,7 @@
 #pragma once
 // Header with all metal stuff available for use with C++ (rather than Objective-C++)
 
-#ifdef __APPLE__
+#ifdef ENABLE_METAL
 
 #include "HostDisplay.h"
 
diff --git a/pcsx2/GS/Window/GSwxDialog.cpp b/pcsx2/GS/Window/GSwxDialog.cpp
index 7c080e0b6e311..cd4bfa337543d 100644
--- a/pcsx2/GS/Window/GSwxDialog.cpp
+++ b/pcsx2/GS/Window/GSwxDialog.cpp
@@ -94,7 +94,7 @@ namespace
 			, inner(new wxBoxSizer(orientation))
 		{
 			wxSizerFlags flags = wxSizerFlags().Expand();
-#ifdef __APPLE__
+#ifdef ENABLE_METAL
 			if (!std::is_same<OuterSizer, wxStaticBoxSizer>::value) // wxMac already adds padding to static box sizers
 #endif
 				flags.Border();
@@ -700,7 +700,7 @@ void Dialog::RendererChange()
 		list = VulkanHostDisplay::StaticGetAdapterAndModeList(nullptr);
 		break;
 #endif
-#ifdef __APPLE__
+#ifdef ENABLE_METAL
 	case GSRendererType::Metal:
 		list = GetMetalAdapterAndModeList();
 		break;
diff --git a/pcsx2/HostDisplay.cpp b/pcsx2/HostDisplay.cpp
index 576c1ea0bfe08..e083acfebf74a 100644
--- a/pcsx2/HostDisplay.cpp
+++ b/pcsx2/HostDisplay.cpp
@@ -134,7 +134,7 @@ std::unique_ptr<HostDisplay> HostDisplay::CreateDisplayForAPI(RenderAPI api)
 		case RenderAPI::D3D11:
 			return std::make_unique<D3D11HostDisplay>();
 #endif
-#ifdef __APPLE__
+#ifdef ENABLE_METAL
 		case HostDisplay::RenderAPI::Metal:
 			return std::unique_ptr<HostDisplay>(MakeMetalHostDisplay());
 #endif