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assemblers
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README.md

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## Data
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Associated sequencing data have been deposited at the European Genome-phenome Archive under the accession number EGAS00001005410.
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Associated sequencing data have been deposited at the European Genome-phenome Archive under the accession number EGAS00001006576 and EGAS00001006629.

genomics/README.md

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## Targeted assembly
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[Lorax](https://github.com/tobiasrausch/lorax) can be used to select reads for a targeted amplicon assembly using phased germline variants and amplicon regions from a somatic copy-number alteration analysis (SCNAs) as input. Selected reads can then be used with any long-read assembler, our choice in this project was [wtdbg2](https://github.com/ruanjue/wtdbg2). Lastly, we projected the alignments back to the reference to infer SV breakpoints.
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[Lorax](https://github.com/tobiasrausch/lorax) can be used to select reads for a targeted amplicon assembly using phased germline variants and amplicon regions from a somatic copy-number alteration analysis (SCNAs) as input. Selected reads can then be used with any long-read assembler, our choice in this project was [wtdbg2](https://github.com/ruanjue/wtdbg2), [flye](https://github.com/fenderglass/Flye) and [shasta](https://github.com/chanzuckerberg/shasta). Lastly, we projected the alignments back to the reference to infer SV breakpoints.
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`cd targeted_assembly/ && ./assemble.sh`
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