diff --git a/python/CuTeDSL/cutlass/base_dsl/ast_preprocessor.py b/python/CuTeDSL/cutlass/base_dsl/ast_preprocessor.py
index 11f2d1ae84..dd1b4b7311 100644
--- a/python/CuTeDSL/cutlass/base_dsl/ast_preprocessor.py
+++ b/python/CuTeDSL/cutlass/base_dsl/ast_preprocessor.py
@@ -304,9 +304,21 @@ def transform_function(self, func_name, function_pointer):
             return []
 
         # Step 1. Parse the given function
-        file_name = inspect.getsourcefile(function_pointer)
-        lines, start_line = inspect.getsourcelines(function_pointer)
-        dedented_source = textwrap.dedent("".join(lines))
+        try:
+            file_name = inspect.getsourcefile(function_pointer)
+            lines, start_line = inspect.getsourcelines(function_pointer)
+            dedented_source = textwrap.dedent("".join(lines))
+        except (OSError, TypeError):
+            # Handle interactive mode (e.g., Python shell, Jupyter) where source is not available
+            # In this case, we cannot preprocess the function
+            log().warning(
+                "Cannot get source code for function [%s]. "
+                "Interactive mode (Python shell/Jupyter) is not supported for preprocessing. "
+                "Please define functions in a .py file instead.",
+                func_name
+            )
+            return []
+        
         tree = ast.parse(dedented_source, filename=file_name)
         # Bump the line numbers so they match the real source file
         ast.increment_lineno(tree, start_line - 1)
@@ -446,7 +458,12 @@ def transform(self, original_function, exec_globals):
         """
         Transforms the provided function using the preprocessor.
         """
-        self.file_name = inspect.getsourcefile(original_function)
+        try:
+            self.file_name = inspect.getsourcefile(original_function)
+        except (OSError, TypeError):
+            # Interactive mode - use placeholder filename
+            self.file_name = "<interactive>"
+        
         self.function_globals = exec_globals
         transformed_tree = self.transform_function(
             original_function.__name__, original_function
diff --git a/python/CuTeDSL/cutlass/base_dsl/dsl.py b/python/CuTeDSL/cutlass/base_dsl/dsl.py
index 2b17d22b1e..7cf0f7579c 100644
--- a/python/CuTeDSL/cutlass/base_dsl/dsl.py
+++ b/python/CuTeDSL/cutlass/base_dsl/dsl.py
@@ -1259,7 +1259,12 @@ def run_preprocessor(self, funcBody):
         return None
 
     def get_function_ptr(self, original_function):
-        file_name = inspect.getsourcefile(original_function)
+        try:
+            file_name = inspect.getsourcefile(original_function)
+        except (OSError, TypeError):
+            # Interactive mode - use placeholder filename
+            file_name = "<interactive>"
+        
         code_object = compile(
             original_function._transformed_ast, filename=file_name, mode="exec"
         )