diff --git a/apps/minimal/tests/cocotb/prepare.sh b/apps/minimal/tests/cocotb/prepare.sh
index 8f9ade14c..27fb6cdee 100755
--- a/apps/minimal/tests/cocotb/prepare.sh
+++ b/apps/minimal/tests/cocotb/prepare.sh
@@ -1,26 +1,9 @@
 #!/bin/sh
 
-OFM_PATH=../../../../
+NDK_FPGA_PATH=../../../..
+source $NDK_FPGA_PATH/env.sh
 
-#swbase=../../../swbase/
-swbase=git+https://github.com/CESNET/ndk-sw.git#subdirectory=
+ndk_fpga_venv_prepare "venv-cocotb"
 
-PKG_PYNFB=${swbase}pynfb/
-PKG_LIBNFBEXT_PYTHON=${swbase}ext/libnfb_ext_python/
-PKG_COCOTBEXT_OFM=$OFM_PATH/python/cocotbext/
-
-# Python virtual environment
-python -m venv venv-cocotb
-source venv-cocotb/bin/activate
-
-python -m pip install cython wheel setuptools
-python -m pip install pylibfdt fdt
-python -m pip install scapy
-python -m pip wheel -w ./cocotbwheels $PKG_PYNFB
-python -m pip install --find-links ./cocotbwheels nfb
-python -m pip install --find-links ./cocotbwheels $PKG_LIBNFBEXT_PYTHON
-python -m pip install $PKG_COCOTBEXT_OFM
-
-echo ""
-echo "Now activate environment with:"
-echo "source venv-cocotb/bin/activate"
+pip install .
+#pip install "cocotbext-ofm[nfb]@$NDK_FPGA_COCOTBEXT_OFM_URL"
diff --git a/apps/minimal/tests/cocotb/pyproject.toml b/apps/minimal/tests/cocotb/pyproject.toml
new file mode 100644
index 000000000..e19b41831
--- /dev/null
+++ b/apps/minimal/tests/cocotb/pyproject.toml
@@ -0,0 +1,10 @@
+[project]
+name = "cocotb-ndk-minimal-test-toplevel"
+version = "0.1.0"
+dependencies = [
+	"cocotbext-ofm[nfb] @ ${NDK_FPGA_COCOTBEXT_OFM_URL}",
+]
+
+[build-system]
+requires = ["pdm-backend"]
+build-backend = "pdm.backend"
diff --git a/apps/minimal/tests/cocotb/top-level-sim.jenkinsfile b/apps/minimal/tests/cocotb/top-level-sim.jenkinsfile
index 49056583a..5973d30c2 100644
--- a/apps/minimal/tests/cocotb/top-level-sim.jenkinsfile
+++ b/apps/minimal/tests/cocotb/top-level-sim.jenkinsfile
@@ -27,13 +27,8 @@ def CARDS = ["alveo-u200", "alveo-u55c", "vcu118", "ia-420f", "n6010", "fb2cghh"
 
 node("preklad") {
     cleanWs()
-    def swbase = "ndk-sw"
     checkout scm
 
-    stage("Clone required repository") {
-        sh "git clone https://github.com/CESNET/ndk-sw.git"
-    }
-
     if (params.nightly != null && params.nightly == true) {
         stage("Prepare for nightly build") {
             sh "(cd extra/nfb-200g2ql; git checkout main)"
@@ -41,17 +36,11 @@ node("preklad") {
         }
     }
 
-    sh "python3.9 -m venv venv-cocotb"
-
     stage("Prepare environment") {
         sh """
-            source venv-cocotb/bin/activate
-            python3.9 -m pip install cython wheel
-            python3.9 -m pip install pylibfdt fdt
-            python3.9 -m pip wheel -w ./cocotbwheels ${swbase}/pynfb/
-            python3.9 -m pip install --find-links ./cocotbwheels nfb
-            python3.9 -m pip install --find-links ./cocotbwheels ${swbase}/ext/libnfb_ext_python/
-            python3.9 -m pip install python/cocotbext/
+            source ./env.sh
+            ndk_fpga_venv_prepare "venv-cocotb"
+            pip install apps/minimal/tests/cocotb
         """
     }
 
diff --git a/build/common.sh b/build/common.sh
new file mode 100644
index 000000000..dfbd31109
--- /dev/null
+++ b/build/common.sh
@@ -0,0 +1,12 @@
+# Common functions
+function ndk_fpga_venv_prepare {
+	if [ -z "$1" ]; then
+		VENV_NAME="venv-cocotb"
+	else
+		VENV_NAME="$1"
+	fi
+
+	echo "Creating virtual environment '$VENV_NAME'"
+	python -m venv $VENV_NAME
+	source $VENV_NAME/bin/activate
+}
diff --git a/core/cocotb/prepare.sh b/core/cocotb/prepare.sh
deleted file mode 100755
index 3bfb13e3b..000000000
--- a/core/cocotb/prepare.sh
+++ /dev/null
@@ -1,28 +0,0 @@
-#!/bin/sh
-# Example script for preparing ndk-app repository to run top-level cocotb simulation
-# Run it once in the build/CARD folder !
-
-# Check base folder
-ls ../../ndk/core/intel/cocotb/examples/cocotb_test.py > /dev/null
-if [ $! ]; then
-	echo "Run this script in the build/CARD folder!"
-	exit 1
-fi
-
-# These commands already done on preklad machines:
-# pip3 install cocotb
-# pip3 install cocotb-bus
-# pip3 install fdt
-# git clone https://github.com/dgibson/dtc.git --branch v1.6.0
-# (cd dtc; make; cd pylibfdt; python3.9 setup.py install --user)
-
-# Install cocotbext-ofm and its cocotbext.axi4stream dependency
-pip3 install git+https://github.com/martinspinler/cocotbext-axi4stream.git#egg=cocotbext.axi4stream -U
-pip3 install git+ssh://git@gitlab.liberouter.org/ndk/cocotbext.git#egg=cocotbext-ofm -U
-
-# Use example test
-cp ../../ndk/core/intel/cocotb/examples/cocotb_test* ./
-
-# Run simulation:
-# make TARGET=cocotb
-echo "Now run simulation with command: make TARGET=cocotb"
diff --git a/core/cocotb/requirements.txt b/core/cocotb/requirements.txt
deleted file mode 100644
index d1e585656..000000000
--- a/core/cocotb/requirements.txt
+++ /dev/null
@@ -1,2 +0,0 @@
-git+https://github.com/martinspinler/cocotbext-axi4stream.git#egg=cocotbext.axi4stream
-git+ssh://git@gitlab.liberouter.org/ndk/cocotbext-ofm.git#egg=cocotbext-ofm
diff --git a/env.sh b/env.sh
new file mode 100644
index 000000000..9c208165b
--- /dev/null
+++ b/env.sh
@@ -0,0 +1,22 @@
+#!/bin/sh
+if [ -z "${NDK_FPGA_PATH}" ]; then
+	NDK_FPGA_PATH=$(dirname "${BASH_SOURCE[0]}")
+fi
+
+source $NDK_FPGA_PATH/build/common.sh
+
+
+# REALPATHs are necessary for local Python packages based on PDM
+NDK_FPGA_REALPATH=$(realpath $NDK_FPGA_PATH)
+
+# ####################################################################
+# Default package paths
+
+# OFM extension for cocotb
+export NDK_FPGA_COCOTBEXT_OFM_URL="file://${NDK_FPGA_REALPATH}/python/cocotbext/"
+
+# NDK software Python packages are dependencies of cocotbext-ofm[nfb]
+export NDK_SW_PYTHON_URL="git+https://github.com/CESNET/ndk-sw.git#subdirectory="
+# NDK software alternative path for local ndk-sw repository
+#NDK_SW_REALPATH=$(realpath $NDK_FPGA_PATH/../swbase)
+#NDK_SW_PYTHON_URL="file:///$(realpath $NDK_SW_PATH)/"
diff --git a/python/cocotbext/pyproject.toml b/python/cocotbext/pyproject.toml
new file mode 100644
index 000000000..6a6d5993e
--- /dev/null
+++ b/python/cocotbext/pyproject.toml
@@ -0,0 +1,23 @@
+[project]
+name = "cocotbext-ofm"
+version = "0.1.0"
+dependencies = [
+	"cocotb",
+	"cocotb-bus",
+]
+
+[project.optional-dependencies]
+nfb = [
+	"pylibfdt",
+	"nfb @ ${NDK_SW_PYTHON_URL}pynfb",
+	"libnfb-ext-python @ ${NDK_SW_PYTHON_URL}ext/libnfb_ext_python",
+]
+
+[build-system]
+requires = [
+	"pdm-backend",
+]
+build-backend = "pdm.backend"
+
+[tool.pdm.build]
+includes = ["cocotbext"]
diff --git a/python/cocotbext/setup.py b/python/cocotbext/setup.py
index 6a7afe961..e32476360 100644
--- a/python/cocotbext/setup.py
+++ b/python/cocotbext/setup.py
@@ -11,7 +11,7 @@
 
     keywords=['python'],
     packages=find_namespace_packages(include=["cocotbext.*"]),
-    install_requires=["cocotb", "cocotb-bus"],
+    install_requires=["cocotb", "cocotb-bus", "pylibfdt"],
     python_requires=">=3.5",
     classifiers=[
         "Programming Language :: Python :: 3",