diff --git a/.flake8 b/.flake8
new file mode 100644
index 00000000..b5874ff1
--- /dev/null
+++ b/.flake8
@@ -0,0 +1,5 @@
+[flake8]
+ignore = E226
+max-line-length = 120
+exclude = tests/*
+max-complexity = 10
\ No newline at end of file
diff --git a/base/application.py b/base/application.py
index 6d5abff3..43655d33 100644
--- a/base/application.py
+++ b/base/application.py
@@ -219,4 +219,4 @@ def internal_server_error(e):
from base.task import *
from base.views import *
from base.views.api import *
-from base.manage import (initdb)
+from base.manage import (init_db)
diff --git a/base/constants.py b/base/constants.py
index fb66fc8b..4bec4a93 100644
--- a/base/constants.py
+++ b/base/constants.py
@@ -2,11 +2,12 @@
"""
This page is intended to store application constants that change
-very infrequently (if ever).
+very infrequently (if ever).
Author: Daniel E. Cook (danielecook@gmail.com)
"""
+
# PRICES
class PRICES:
DIVERGENT_SET = 160
@@ -14,6 +15,7 @@ class PRICES:
STRAIN = 15
SHIPPING = 65
+
# BUILDS AND RELEASES
WORMBASE_BUILD = "WS261"
RELEASES = ["20170531",
@@ -21,9 +23,6 @@ class PRICES:
CURRENT_RELEASE = RELEASES[0]
-# URLS
-BAM_URL_PREFIX = "https://elegansvariation.org.s3.amazonaws.com/bam"
-
# Maps chromosome in roman numerals to integer
CHROM_NUMERIC = {"I": 1,
"II": 2,
@@ -31,4 +30,42 @@ class PRICES:
"IV": 4,
"V": 5,
"X": 6,
- "MtDNA": 7}
\ No newline at end of file
+ "MtDNA": 7}
+
+
+class URLS:
+ """
+ URLs are stored here so they can be easily integrated into the database
+ for provenance purposes.
+ """
+
+ #
+ # AWS URLS
+ #
+ BAM_URL_PREFIX = "https://elegansvariation.org.s3.amazonaws.com/bam"
+
+ #
+ # Wormbase URLs
+ #
+
+ # Gene GTF
+ GENE_GTF_URL = f"ftp://ftp.wormbase.org/pub/wormbase/releases/{WORMBASE_BUILD}/species/c_elegans/PRJNA13758/c_elegans.PRJNA13758.{WORMBASE_BUILD}.canonical_geneset.gtf.gz"
+
+ # GENE GFF_URL
+ GENE_GFF_URL = f"ftp://ftp.wormbase.org/pub/wormbase/releases/{WORMBASE_BUILD}/species/c_elegans/PRJNA13758/c_elegans.PRJNA13758.{WORMBASE_BUILD}.annotations.gff3.gz"
+
+ # Maps wormbase ID to locus name
+ GENE_IDS_URL = f"ftp://ftp.wormbase.org/pub/wormbase/species/c_elegans/annotation/geneIDs/c_elegans.PRJNA13758.current.geneIDs.txt.gz"
+
+ # Lists C. elegans orthologs
+ ORTHOLOG_URL = f"ftp://ftp.wormbase.org/pub/wormbase/species/c_elegans/PRJNA13758/annotation/orthologs/c_elegans.PRJNA13758.current_development.orthologs.txt"
+
+ #
+ # Ortholog URLs
+ #
+
+ # Homologene
+ HOMOLOGENE_URL = 'https://ftp.ncbi.nih.gov/pub/HomoloGene/current/homologene.data'
+
+ # Taxon IDs
+ TAXON_ID_URL = 'ftp://ftp.ncbi.nih.gov/pub/taxonomy/taxdump.tar.gz'
diff --git a/base/db/etl_homologene.py b/base/db/etl_homologene.py
index 46ba4dab..0f594c82 100644
--- a/base/db/etl_homologene.py
+++ b/base/db/etl_homologene.py
@@ -9,15 +9,10 @@
import tarfile
import csv
import requests
-from base.db.etl_wormbase import get_gene_ids
-from urllib.request import urlretrieve, urlopen
+from urllib.request import urlretrieve
from tempfile import NamedTemporaryFile
from base.models2 import wormbase_gene_summary_m
-
-
-# Homologene database
-HOMOLOGENE_URL = 'https://ftp.ncbi.nih.gov/pub/HomoloGene/current/homologene.data'
-TAXON_ID_URL = 'ftp://ftp.ncbi.nih.gov/pub/taxonomy/taxdump.tar.gz'
+from base.constants import URLS
def fetch_taxon_ids():
@@ -25,13 +20,13 @@ def fetch_taxon_ids():
Downloads mapping of taxon-ids to species names.
"""
taxon_file = NamedTemporaryFile(suffix='tar')
- out, err = urlretrieve(TAXON_ID_URL, taxon_file.name)
+ out, err = urlretrieve(URLS.TAXON_ID_URL, taxon_file.name)
tar = tarfile.open(out)
# Read names file
names_dmp = tar.extractfile('names.dmp')
names_dmp = names_dmp.read().decode('utf-8').splitlines()
lines = [re.split('\t\|[\t]?', x) for x in names_dmp]
- taxon_ids = {int(l[0]):l[1] for l in lines if l[3] == 'scientific name'}
+ taxon_ids = {int(l[0]): l[1] for l in lines if l[3] == 'scientific name'}
return taxon_ids
@@ -58,21 +53,10 @@ def fetch_homologene():
* gene_symbol = Gene Symbol
* species = species name
"""
- response = requests.get(HOMOLOGENE_URL)
+ response = requests.get(URLS.HOMOLOGENE_URL)
response_csv = list(csv.reader(response.content.decode('utf-8').splitlines(), delimiter='\t'))
-
- taxon_ids = fetch_taxon_ids()
- # In this loop we add the homologene id (line[0]) if there's a c_elegans gene
- # (line[1]) in the group.
- fields = ['homologene',
- 'taxon_id',
- 'gene_id',
- 'gene_symbol',
- 'protein_gi',
- 'protein_accession',
- 'species',
- 'locus_name']
+ taxon_ids = fetch_taxon_ids()
# First, fetch records with a homolog ID that possesses a C. elegans gene.
elegans_set = dict([[int(x[0]), x[3]] for x in response_csv if x[1] == '6239'])
@@ -91,4 +75,3 @@ def fetch_homologene():
'homolog_gene': line[3],
'homolog_source': "Homologene",
'is_ortholog': False}
-
diff --git a/base/db/etl_strains.py b/base/db/etl_strains.py
index 4c501fe0..64b24b76 100644
--- a/base/db/etl_strains.py
+++ b/base/db/etl_strains.py
@@ -13,15 +13,22 @@
from base.utils.google_sheets import get_google_sheet
from base.utils.gcloud import get_item
from logzero import logger
-ELEVATION_API_KEY=elevation_api_key = get_item('credential', 'elevation').get('apiKey')
+
+# Not a constant!
+ELEVATION_API_KEY = get_item('credential', 'elevation').get('apiKey')
@lru_cache(maxsize=32)
def fetch_elevations(lat, lon):
"""
- Fetch elevation
+ Fetch elevation.
+
+ @lru_cache decorator caches result so we only make one
+ call per unique lat/lon result.
+
"""
- result = requests.get(f"https://maps.googleapis.com/maps/api/elevation/json?locations={lat},{lon}&key={ELEVATION_API_KEY}")
+ elevation_url = f"https://maps.googleapis.com/maps/api/elevation/json?locations={lat},{lon}&key={ELEVATION_API_KEY}"
+ result = requests.get(elevation_url)
if result.ok:
elevation = result.json()['results'][0]['elevation']
return elevation
@@ -41,10 +48,9 @@ def fetch_andersen_strains():
strain_records = WI.get_all_records()
strain_records = list(filter(lambda x: x.get('isotype') not in ['', None, 'NA'], strain_records))
for n, record in enumerate(strain_records):
- set_list = ','.join([set_name.split("_")[1] for set_name, set_val in record.items()
+ set_list = ','.join([set_name.split("_")[1] for set_name, set_val in record.items()
if 'set_' in set_name and set_val == "TRUE"])
record['sets'] = set_list
- latlon_set = []
for k, v in record.items():
# Set NA to None
if v in ["NA", '']:
@@ -56,4 +62,4 @@ def fetch_andersen_strains():
record['elevation'] = fetch_elevations(record['latitude'], record['longitude'])
if n % 50 == 0:
logger.info(f"Loaded {n} strains")
- return strain_records
\ No newline at end of file
+ return strain_records
diff --git a/base/db/etl_wormbase.py b/base/db/etl_wormbase.py
index e74f9d85..556fd095 100644
--- a/base/db/etl_wormbase.py
+++ b/base/db/etl_wormbase.py
@@ -2,7 +2,7 @@
"""
Functions in this script are used to load
-information from wormbase into the
+information from wormbase into the
CeNDR database
Author: Daniel E. Cook (danielecook@gmail.com)
@@ -11,25 +11,11 @@
import csv
import gzip
from gtfparse import read_gtf_as_dataframe
-from urllib.request import urlretrieve, urlopen
+from urllib.request import urlretrieve
from tempfile import NamedTemporaryFile
-from base.constants import WORMBASE_BUILD, CHROM_NUMERIC
from base.utils.genetic_utils import arm_or_center
-from base.models2 import wormbase_gene_summary_m
+from base.constants import URLS, CHROM_NUMERIC
-# Gene GTF defines biotype, start, stop, etc.
-# The GTF does not include locus names (pot-2, etc), so we download them in the get_gene_ids function.
-GENE_GTF_URL = f"ftp://ftp.wormbase.org/pub/wormbase/releases/{WORMBASE_BUILD}/species/c_elegans/PRJNA13758/c_elegans.PRJNA13758.{WORMBASE_BUILD}.canonical_geneset.gtf.gz"
-
-
-# GENE GFF_URL
-GENE_GFF_URL = f"ftp://ftp.wormbase.org/pub/wormbase/releases/{WORMBASE_BUILD}/species/c_elegans/PRJNA13758/c_elegans.PRJNA13758.{WORMBASE_BUILD}.annotations.gff3.gz"
-
-# Maps wormbase ID to locus name
-GENE_IDS_URL = f"ftp://ftp.wormbase.org/pub/wormbase/species/c_elegans/annotation/geneIDs/c_elegans.PRJNA13758.current.geneIDs.txt.gz"
-
-# Lists C. elegans orthologs
-ORTHOLOG_URL = f"ftp://ftp.wormbase.org/pub/wormbase/species/c_elegans/PRJNA13758/annotation/orthologs/c_elegans.PRJNA13758.current_development.orthologs.txt"
def get_gene_ids():
"""
@@ -38,10 +24,9 @@ def get_gene_ids():
Gene locus names (e.g. pot-2)
"""
gene_locus_names_file = NamedTemporaryFile('wb', suffix=".gz")
- out, err = urlretrieve(GENE_IDS_URL, gene_locus_names_file.name)
- return dict([x.split(",")[1:3] for x in gzip.open(out, 'r').read().decode('utf-8').splitlines()])
-
-
+ out, err = urlretrieve(URLS.GENE_IDS_URL, gene_locus_names_file.name)
+ results = [x.split(",")[1:3] for x in gzip.open(out, 'r').read().decode('utf-8').splitlines()]
+ return dict(results)
def fetch_gene_gtf():
@@ -51,16 +36,16 @@ def fetch_gene_gtf():
and yields a dictionary for each row.
"""
gene_gtf_file = NamedTemporaryFile('wb', suffix=".gz")
- out, err = urlretrieve(GENE_GTF_URL, gene_gtf_file.name)
+ out, err = urlretrieve(URLS.GENE_GTF_URL, gene_gtf_file.name)
gene_gtf = read_gtf_as_dataframe(gene_gtf_file.name)
gene_ids = get_gene_ids()
# Add locus column
# Rename seqname to chrom
- gene_gtf = gene_gtf.rename({'seqname':'chrom'}, axis='columns')
+ gene_gtf = gene_gtf.rename({'seqname': 'chrom'}, axis='columns')
gene_gtf = gene_gtf.assign(locus=[gene_ids.get(x) for x in gene_gtf.gene_id])
gene_gtf = gene_gtf.assign(chrom_num=[CHROM_NUMERIC[x] for x in gene_gtf.chrom])
- gene_gtf = gene_gtf.assign(pos = (((gene_gtf.end - gene_gtf.start)/2) + gene_gtf.start).map(int))
+ gene_gtf = gene_gtf.assign(pos=(((gene_gtf.end - gene_gtf.start)/2) + gene_gtf.start).map(int))
gene_gtf['arm_or_center'] = gene_gtf.apply(lambda row: arm_or_center(row['chrom'], row['pos']), axis=1)
for row in gene_gtf.to_dict('records'):
yield row
@@ -75,7 +60,7 @@ def fetch_gene_gff_summary():
"""
gene_gff_file = NamedTemporaryFile('wb', suffix=".gz")
- out, err = urlretrieve(GENE_GFF_URL, gene_gff_file.name)
+ out, err = urlretrieve(URLS.GENE_GFF_URL, gene_gff_file.name)
WB_GENE_FIELDSET = ['ID', 'biotype', 'sequence_name', 'chrom', 'start', 'end', 'locus']
@@ -88,7 +73,7 @@ def fetch_gene_gff_summary():
gene.update(zip(["chrom", "start", "end"],
[line[0], line[3], line[4]]))
gene = {k.lower(): v for k, v in gene.items() if k in WB_GENE_FIELDSET}
-
+
# Change add chrom_num
gene['chrom_num'] = CHROM_NUMERIC[gene['chrom']]
gene['start'] = int(gene['start'])
@@ -110,7 +95,7 @@ def fetch_orthologs():
Fetches orthologs from wormbase; Stored in the homolog table.
"""
orthologs_file = NamedTemporaryFile('wb', suffix=".txt")
- out, err = urlretrieve(ORTHOLOG_URL , orthologs_file.name)
+ out, err = urlretrieve(URLS.ORTHOLOG_URL, orthologs_file.name)
csv_out = list(csv.reader(open(out, 'r'), delimiter='\t'))
for line in csv_out:
@@ -126,4 +111,4 @@ def fetch_orthologs():
'homolog_taxon_id': None,
'homolog_gene': line[2],
'homolog_source': line[3],
- 'is_ortholog': line[0] == 'Caenorhabditis elegans'}
\ No newline at end of file
+ 'is_ortholog': line[0] == 'Caenorhabditis elegans'}
diff --git a/base/manage.py b/base/manage.py
index a81a8ca8..fb280463 100644
--- a/base/manage.py
+++ b/base/manage.py
@@ -2,13 +2,21 @@
import arrow
from click import secho
from base.application import app, db_2
-from base.models2 import strain_m, wormbase_gene_summary_m, wormbase_gene_m, homologs_m
+from base.models2 import (metadata_m,
+ strain_m,
+ wormbase_gene_summary_m,
+ wormbase_gene_m,
+ homologs_m)
from base.db.etl_strains import fetch_andersen_strains
-from base.db.etl_wormbase import fetch_gene_gtf, fetch_gene_gff_summary, fetch_orthologs
+from base.db.etl_wormbase import (fetch_gene_gtf,
+ fetch_gene_gff_summary,
+ fetch_orthologs)
from base.db.etl_homologene import fetch_homologene
+from base import constants
+
@app.cli.command()
-def initdb():
+def init_db():
"""Initialize the database."""
start = arrow.utcnow()
secho('Initializing Database', fg="green")
@@ -18,6 +26,31 @@ def initdb():
secho('Created cendr.db', fg="green")
+ ################
+ # Set metadata #
+ ################
+ secho('Inserting metadata', fg="green")
+ date_created = metadata_m(key="date_created", value=arrow.utcnow().datetime.isoformat())
+ db_2.session.add(date_created)
+ for var in vars(constants):
+ if not var.startswith("_"):
+ # For nested constants:
+ current_var = getattr(constants, var)
+ if type(current_var) == type:
+ for name in [x for x in vars(current_var) if not x.startswith("_")]:
+ key_val = metadata_m(key="{}/{}".format(var, name),
+ value=getattr(current_var, name))
+ db_2.session.add(key_val)
+ elif type(current_var) == list:
+ key_val = metadata_m(key=var,
+ value=','.join(getattr(constants, var)))
+ db_2.session.add(key_val)
+ else:
+ key_val = metadata_m(key=var, value=str(getattr(constants, var)))
+ db_2.session.add(key_val)
+
+ db_2.session.commit()
+
##############
# Load Genes #
##############
@@ -39,7 +72,7 @@ def initdb():
db_2.session.bulk_insert_mappings(homologs_m, fetch_homologene())
secho('Loading orthologs from WormBase', fg='green')
db_2.session.bulk_insert_mappings(homologs_m, fetch_orthologs())
-
+
################
# Load Strains #
################
@@ -48,4 +81,6 @@ def initdb():
db_2.session.commit()
secho(f"Inserted {strain_m.query.count()} strains", fg="blue")
diff = int((arrow.utcnow() - start).total_seconds())
- secho(f"{diff} seconds")
\ No newline at end of file
+ secho(f"{diff} seconds")
+
+
diff --git a/base/models2.py b/base/models2.py
index 38b23fa2..52b384c4 100644
--- a/base/models2.py
+++ b/base/models2.py
@@ -1,10 +1,20 @@
from flask import Markup
from base.application import db_2
-from base.constants import BAM_URL_PREFIX
+from base.constants import URLS
from sqlalchemy import or_, func
+class metadata_m(db_2.Model):
+ """
+ Table for storing information about other tables
+ """
+ __tablename__ = "metadata"
+ key = db_2.Column(db_2.String(50), index=True, primary_key=True)
+ value = db_2.Column(db_2.String)
+
+
+
class strain_m(db_2.Model):
__tablename__ = "strain"
strain = db_2.Column(db_2.String(25), primary_key=True)
@@ -41,11 +51,11 @@ def bam_url(self):
"""
url_set = Markup(f"""
-
+
BAM
/
-
+
bai
""".strip())
@@ -139,3 +149,4 @@ def unnest(self):
def __repr__(self):
return f"homolog: {self.gene_name} -- {self.homolog_gene}"
+
diff --git a/base/static/css/bootstrap.css b/base/static/css/bootstrap.css
deleted file mode 100644
index c5502f38..00000000
--- a/base/static/css/bootstrap.css
+++ /dev/null
@@ -1,5774 +0,0 @@
-/*! normalize.css v3.0.0 | MIT License | git.io/normalize */
-html {
- font-family: sans-serif;
- -ms-text-size-adjust: 100%;
- -webkit-text-size-adjust: 100%;
-}
-body {
- margin: 0;
-}
-article,
-aside,
-details,
-figcaption,
-figure,
-footer,
-header,
-hgroup,
-main,
-nav,
-section,
-summary {
- display: block;
-}
-audio,
-canvas,
-progress,
-video {
- display: inline-block;
- vertical-align: baseline;
-}
-audio:not([controls]) {
- display: none;
- height: 0;
-}
-[hidden],
-template {
- display: none;
-}
-a {
- background: transparent;
-}
-a:active,
-a:hover {
- outline: 0;
-}
-abbr[title] {
- border-bottom: 1px dotted;
-}
-b,
-strong {
- font-weight: bold;
-}
-dfn {
- font-style: italic;
-}
-h1 {
- font-size: 2em;
- margin: 0.67em 0;
-}
-mark {
- background: #ff0;
- color: #000;
-}
-small {
- font-size: 80%;
-}
-sub,
-sup {
- font-size: 75%;
- line-height: 0;
- position: relative;
- vertical-align: baseline;
-}
-sup {
- top: -0.5em;
-}
-sub {
- bottom: -0.25em;
-}
-img {
- border: 0;
-}
-svg:not(:root) {
- overflow: hidden;
-}
-figure {
- margin: 1em 40px;
-}
-hr {
- -moz-box-sizing: content-box;
- box-sizing: content-box;
- height: 0;
-}
-pre {
- overflow: auto;
-}
-code,
-kbd,
-pre,
-samp {
- font-family: monospace, monospace;
- font-size: 1em;
-}
-button,
-input,
-optgroup,
-select,
-textarea {
- color: inherit;
- font: inherit;
- margin: 0;
-}
-button {
- overflow: visible;
-}
-button,
-select {
- text-transform: none;
-}
-button,
-html input[type="button"],
-input[type="reset"],
-input[type="submit"] {
- -webkit-appearance: button;
- cursor: pointer;
-}
-button[disabled],
-html input[disabled] {
- cursor: default;
-}
-button::-moz-focus-inner,
-input::-moz-focus-inner {
- border: 0;
- padding: 0;
-}
-input {
- line-height: normal;
-}
-input[type="checkbox"],
-input[type="radio"] {
- box-sizing: border-box;
- padding: 0;
-}
-input[type="number"]::-webkit-inner-spin-button,
-input[type="number"]::-webkit-outer-spin-button {
- height: auto;
-}
-input[type="search"] {
- -webkit-appearance: textfield;
- -moz-box-sizing: content-box;
- -webkit-box-sizing: content-box;
- box-sizing: content-box;
-}
-input[type="search"]::-webkit-search-cancel-button,
-input[type="search"]::-webkit-search-decoration {
- -webkit-appearance: none;
-}
-fieldset {
- border: 1px solid #c0c0c0;
- margin: 0 2px;
- padding: 0.35em 0.625em 0.75em;
-}
-legend {
- border: 0;
- padding: 0;
-}
-textarea {
- overflow: auto;
-}
-optgroup {
- font-weight: bold;
-}
-table {
- border-collapse: collapse;
- border-spacing: 0;
-}
-td,
-th {
- padding: 0;
-}
-@media print {
- * {
- text-shadow: none !important;
- color: #000 !important;
- background: transparent !important;
- box-shadow: none !important;
- }
- a,
- a:visited {
- text-decoration: underline;
- }
- a[href]:after {
- content: " (" attr(href) ")";
- }
- abbr[title]:after {
- content: " (" attr(title) ")";
- }
- a[href^="javascript:"]:after,
- a[href^="#"]:after {
- content: "";
- }
- pre,
- blockquote {
- border: 1px solid #999;
- page-break-inside: avoid;
- }
- thead {
- display: table-header-group;
- }
- tr,
- img {
- page-break-inside: avoid;
- }
- img {
- max-width: 100% !important;
- }
- p,
- h2,
- h3 {
- orphans: 3;
- widows: 3;
- }
- h2,
- h3 {
- page-break-after: avoid;
- }
- select {
- background: #fff !important;
- }
- .navbar {
- display: none;
- }
- .table td,
- .table th {
- background-color: #fff !important;
- }
- .btn > .caret,
- .dropup > .btn > .caret {
- border-top-color: #000 !important;
- }
- .label {
- border: 1px solid #000;
- }
- .table {
- border-collapse: collapse !important;
- }
- .table-bordered th,
- .table-bordered td {
- border: 1px solid #ddd !important;
- }
-}
-* {
- -webkit-box-sizing: border-box;
- -moz-box-sizing: border-box;
- box-sizing: border-box;
-}
-*:before,
-*:after {
- -webkit-box-sizing: border-box;
- -moz-box-sizing: border-box;
- box-sizing: border-box;
-}
-html {
- font-size: 62.5%;
- -webkit-tap-highlight-color: rgba(0, 0, 0, 0);
-}
-body {
- font-family: "Helvetica Neue", Helvetica, Arial, sans-serif;
- font-size: 14px;
- line-height: 1.42857143;
- color: #333333;
- background-color: #ffffff;
-}
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- box-shadow: 0 5px 15px rgba(0, 0, 0, 0.5);
- }
- .modal-sm {
- width: 300px;
- }
-}
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- width: 900px;
- }
-}
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- display: block;
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-}
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- opacity: 0.9;
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- margin-left: 3px;
- padding: 0 5px;
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- background-color: #000000;
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-}
-.tooltip-arrow {
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- height: 0;
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-}
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- margin-left: -5px;
- border-width: 5px 5px 0;
- border-top-color: #000000;
-}
-.tooltip.top-left .tooltip-arrow {
- bottom: 0;
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- border-top-color: #000000;
-}
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- border-top-color: #000000;
-}
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-}
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-}
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- top: 0;
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- border-bottom-color: #000000;
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- top: 0;
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- z-index: 1010;
- display: none;
- max-width: 276px;
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- background-color: #ffffff;
- background-clip: padding-box;
- border: 1px solid #cccccc;
- border: 1px solid rgba(0, 0, 0, 0.2);
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- -webkit-box-shadow: 0 5px 10px rgba(0, 0, 0, 0.2);
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-}
-.popover.top {
- margin-top: -10px;
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-.popover.right {
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- margin: 0;
- padding: 8px 14px;
- font-size: 14px;
- font-weight: normal;
- line-height: 18px;
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- border-bottom: 1px solid #ebebeb;
- border-radius: 5px 5px 0 0;
-}
-.popover-content {
- padding: 9px 14px;
-}
-.popover > .arrow,
-.popover > .arrow:after {
- position: absolute;
- display: block;
- width: 0;
- height: 0;
- border-color: transparent;
- border-style: solid;
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-.popover > .arrow {
- border-width: 11px;
-}
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- border-width: 10px;
- content: "";
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- left: 50%;
- margin-left: -11px;
- border-bottom-width: 0;
- border-top-color: #999999;
- border-top-color: rgba(0, 0, 0, 0.25);
- bottom: -11px;
-}
-.popover.top > .arrow:after {
- content: " ";
- bottom: 1px;
- margin-left: -10px;
- border-bottom-width: 0;
- border-top-color: #ffffff;
-}
-.popover.right > .arrow {
- top: 50%;
- left: -11px;
- margin-top: -11px;
- border-left-width: 0;
- border-right-color: #999999;
- border-right-color: rgba(0, 0, 0, 0.25);
-}
-.popover.right > .arrow:after {
- content: " ";
- left: 1px;
- bottom: -10px;
- border-left-width: 0;
- border-right-color: #ffffff;
-}
-.popover.bottom > .arrow {
- left: 50%;
- margin-left: -11px;
- border-top-width: 0;
- border-bottom-color: #999999;
- border-bottom-color: rgba(0, 0, 0, 0.25);
- top: -11px;
-}
-.popover.bottom > .arrow:after {
- content: " ";
- top: 1px;
- margin-left: -10px;
- border-top-width: 0;
- border-bottom-color: #ffffff;
-}
-.popover.left > .arrow {
- top: 50%;
- right: -11px;
- margin-top: -11px;
- border-right-width: 0;
- border-left-color: #999999;
- border-left-color: rgba(0, 0, 0, 0.25);
-}
-.popover.left > .arrow:after {
- content: " ";
- right: 1px;
- border-right-width: 0;
- border-left-color: #ffffff;
- bottom: -10px;
-}
-.carousel {
- position: relative;
-}
-.carousel-inner {
- position: relative;
- overflow: hidden;
- width: 100%;
-}
-.carousel-inner > .item {
- display: none;
- position: relative;
- -webkit-transition: 0.6s ease-in-out left;
- transition: 0.6s ease-in-out left;
-}
-.carousel-inner > .item > img,
-.carousel-inner > .item > a > img {
- line-height: 1;
-}
-.carousel-inner > .active,
-.carousel-inner > .next,
-.carousel-inner > .prev {
- display: block;
-}
-.carousel-inner > .active {
- left: 0;
-}
-.carousel-inner > .next,
-.carousel-inner > .prev {
- position: absolute;
- top: 0;
- width: 100%;
-}
-.carousel-inner > .next {
- left: 100%;
-}
-.carousel-inner > .prev {
- left: -100%;
-}
-.carousel-inner > .next.left,
-.carousel-inner > .prev.right {
- left: 0;
-}
-.carousel-inner > .active.left {
- left: -100%;
-}
-.carousel-inner > .active.right {
- left: 100%;
-}
-.carousel-control {
- position: absolute;
- top: 0;
- left: 0;
- bottom: 0;
- width: 15%;
- opacity: 0.5;
- filter: alpha(opacity=50);
- font-size: 20px;
- color: #ffffff;
- text-align: center;
- text-shadow: 0 1px 2px rgba(0, 0, 0, 0.6);
-}
-.carousel-control.left {
- background-image: -webkit-linear-gradient(left, color-stop(rgba(0, 0, 0, 0.5) 0%), color-stop(rgba(0, 0, 0, 0.0001) 100%));
- background-image: linear-gradient(to right, rgba(0, 0, 0, 0.5) 0%, rgba(0, 0, 0, 0.0001) 100%);
- background-repeat: repeat-x;
- filter: progid:DXImageTransform.Microsoft.gradient(startColorstr='#80000000', endColorstr='#00000000', GradientType=1);
-}
-.carousel-control.right {
- left: auto;
- right: 0;
- background-image: -webkit-linear-gradient(left, color-stop(rgba(0, 0, 0, 0.0001) 0%), color-stop(rgba(0, 0, 0, 0.5) 100%));
- background-image: linear-gradient(to right, rgba(0, 0, 0, 0.0001) 0%, rgba(0, 0, 0, 0.5) 100%);
- background-repeat: repeat-x;
- filter: progid:DXImageTransform.Microsoft.gradient(startColorstr='#00000000', endColorstr='#80000000', GradientType=1);
-}
-.carousel-control:hover,
-.carousel-control:focus {
- outline: none;
- color: #ffffff;
- text-decoration: none;
- opacity: 0.9;
- filter: alpha(opacity=90);
-}
-.carousel-control .icon-prev,
-.carousel-control .icon-next,
-.carousel-control .glyphicon-chevron-left,
-.carousel-control .glyphicon-chevron-right {
- position: absolute;
- top: 50%;
- z-index: 5;
- display: inline-block;
-}
-.carousel-control .icon-prev,
-.carousel-control .glyphicon-chevron-left {
- left: 50%;
-}
-.carousel-control .icon-next,
-.carousel-control .glyphicon-chevron-right {
- right: 50%;
-}
-.carousel-control .icon-prev,
-.carousel-control .icon-next {
- width: 20px;
- height: 20px;
- margin-top: -10px;
- margin-left: -10px;
- font-family: serif;
-}
-.carousel-control .icon-prev:before {
- content: '\2039';
-}
-.carousel-control .icon-next:before {
- content: '\203a';
-}
-.carousel-indicators {
- position: absolute;
- bottom: 10px;
- left: 50%;
- z-index: 15;
- width: 60%;
- margin-left: -30%;
- padding-left: 0;
- list-style: none;
- text-align: center;
-}
-.carousel-indicators li {
- display: inline-block;
- width: 10px;
- height: 10px;
- margin: 1px;
- text-indent: -999px;
- border: 1px solid #ffffff;
- border-radius: 10px;
- cursor: pointer;
- background-color: #000 \9;
- background-color: rgba(0, 0, 0, 0);
-}
-.carousel-indicators .active {
- margin: 0;
- width: 12px;
- height: 12px;
- background-color: #ffffff;
-}
-.carousel-caption {
- position: absolute;
- left: 15%;
- right: 15%;
- bottom: 20px;
- z-index: 10;
- padding-top: 20px;
- padding-bottom: 20px;
- color: #ffffff;
- text-align: center;
- text-shadow: 0 1px 2px rgba(0, 0, 0, 0.6);
-}
-.carousel-caption .btn {
- text-shadow: none;
-}
-@media screen and (min-width: 768px) {
- .carousel-control .glyphicon-chevron-left,
- .carousel-control .glyphicon-chevron-right,
- .carousel-control .icon-prev,
- .carousel-control .icon-next {
- width: 30px;
- height: 30px;
- margin-top: -15px;
- margin-left: -15px;
- font-size: 30px;
- }
- .carousel-caption {
- left: 20%;
- right: 20%;
- padding-bottom: 30px;
- }
- .carousel-indicators {
- bottom: 20px;
- }
-}
-.clearfix:before,
-.clearfix:after,
-.container:before,
-.container:after,
-.container-fluid:before,
-.container-fluid:after,
-.row:before,
-.row:after,
-.form-horizontal .form-group:before,
-.form-horizontal .form-group:after,
-.btn-toolbar:before,
-.btn-toolbar:after,
-.btn-group-vertical > .btn-group:before,
-.btn-group-vertical > .btn-group:after,
-.nav:before,
-.nav:after,
-.navbar:before,
-.navbar:after,
-.navbar-header:before,
-.navbar-header:after,
-.navbar-collapse:before,
-.navbar-collapse:after,
-.pager:before,
-.pager:after,
-.panel-body:before,
-.panel-body:after,
-.modal-footer:before,
-.modal-footer:after {
- content: " ";
- display: table;
-}
-.clearfix:after,
-.container:after,
-.container-fluid:after,
-.row:after,
-.form-horizontal .form-group:after,
-.btn-toolbar:after,
-.btn-group-vertical > .btn-group:after,
-.nav:after,
-.navbar:after,
-.navbar-header:after,
-.navbar-collapse:after,
-.pager:after,
-.panel-body:after,
-.modal-footer:after {
- clear: both;
-}
-.center-block {
- display: block;
- margin-left: auto;
- margin-right: auto;
-}
-.pull-right {
- float: right !important;
-}
-.pull-left {
- float: left !important;
-}
-.hide {
- display: none !important;
-}
-.show {
- display: block !important;
-}
-.invisible {
- visibility: hidden;
-}
-.text-hide {
- font: 0/0 a;
- color: transparent;
- text-shadow: none;
- background-color: transparent;
- border: 0;
-}
-.hidden {
- display: none !important;
- visibility: hidden !important;
-}
-.affix {
- position: fixed;
-}
-@-ms-viewport {
- width: device-width;
-}
-.visible-xs,
-.visible-sm,
-.visible-md,
-.visible-lg {
- display: none !important;
-}
-@media (max-width: 767px) {
- .visible-xs {
- display: block !important;
- }
- table.visible-xs {
- display: table;
- }
- tr.visible-xs {
- display: table-row !important;
- }
- th.visible-xs,
- td.visible-xs {
- display: table-cell !important;
- }
-}
-@media (min-width: 768px) and (max-width: 991px) {
- .visible-sm {
- display: block !important;
- }
- table.visible-sm {
- display: table;
- }
- tr.visible-sm {
- display: table-row !important;
- }
- th.visible-sm,
- td.visible-sm {
- display: table-cell !important;
- }
-}
-@media (min-width: 992px) and (max-width: 1199px) {
- .visible-md {
- display: block !important;
- }
- table.visible-md {
- display: table;
- }
- tr.visible-md {
- display: table-row !important;
- }
- th.visible-md,
- td.visible-md {
- display: table-cell !important;
- }
-}
-@media (min-width: 1200px) {
- .visible-lg {
- display: block !important;
- }
- table.visible-lg {
- display: table;
- }
- tr.visible-lg {
- display: table-row !important;
- }
- th.visible-lg,
- td.visible-lg {
- display: table-cell !important;
- }
-}
-@media (max-width: 767px) {
- .hidden-xs {
- display: none !important;
- }
-}
-@media (min-width: 768px) and (max-width: 991px) {
- .hidden-sm {
- display: none !important;
- }
-}
-@media (min-width: 992px) and (max-width: 1199px) {
- .hidden-md {
- display: none !important;
- }
-}
-@media (min-width: 1200px) {
- .hidden-lg {
- display: none !important;
- }
-}
-.visible-print {
- display: none !important;
-}
-@media print {
- .visible-print {
- display: block !important;
- }
- table.visible-print {
- display: table;
- }
- tr.visible-print {
- display: table-row !important;
- }
- th.visible-print,
- td.visible-print {
- display: table-cell !important;
- }
-}
-@media print {
- .hidden-print {
- display: none !important;
- }
-}
diff --git a/base/static/css/pileup.css b/base/static/css/pileup.css
deleted file mode 100644
index cc42dbc3..00000000
--- a/base/static/css/pileup.css
+++ /dev/null
@@ -1,279 +0,0 @@
-/**
- * This is the default stylesheet for pileup.js.
- * In general, it attempts to look like IGV.
- * You are encouraged to override anything you like.
- */
-
-.pileup-root {
- display: flex;
- flex-direction: column;
- height: 100%;
-}
-
-.pileup-root > .track {
- display: flex;
- flex-direction: row;
-}
-.pileup-root text, .track-label {
- font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;
-}
-.track-label {
- flex: 0 0 100px; /* fixed-width track labels */
- text-align: right;
- font-size: 0.9em;
- position: relative; /* make this an offset parent for positioning the label. */
-}
-.track-label > span {
- padding-right: 5px;
-}
-/* bottom-justify these track labels */
-.track.reference .track-label > span,
-.track.variants .track-label > span
-{
- position: absolute;
- bottom: 0;
- right: 0;
-}
-.track-content {
- flex: 1; /* stretch to fill remaining space */
- overflow-y: auto;
- overflow-x: hidden;
- position: relative;
-}
-.track-content > div {
- position: absolute; /* Gets the child of the flex-item to fill height 100% */
-}
-.track-content canvas {
- display: block;
-}
-
-/* controls */
-.pileup-root > .controls {
- flex: 0 0 30px; /* fixed height */
-}
-.pileup-root > .controls > .track-content {
- overflow: visible;
-}
-.pileup-root > .controls form.controls {
- margin-bottom: 0; /* overrides browser default */
-}
-.pileup-root > .controls .zoom-controls {
- display: inline-block;
-}
-.pileup-root > .controls .btn-zoom-out:before {
- content: '-';
-}
-.pileup-root > .controls .btn-zoom-in:before {
- content: '+';
-}
-.pileup-root > .controls input,
-.pileup-root > .controls button,
-.pileup-root > .controls select,
-.pileup-root > .controls option {
- font-size: 0.9em;
-}
-
-.gear {
- margin-left: 0.5em;
- font-size: 2em;
- color: #666;
-}
-.gear:hover {
- color: black;
-}
-.menu-container {
- z-index: 1;
- width: 250px; /* not really 250px, but clears parent constraint */
-}
-.menu {
- border: 1px solid black;
- border-radius: 2px;
- display: table;
- background: white;
- font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;
- text-align: left;
-}
-.menu-header {
- font-weight: bold;
- border-bottom: 1px solid #777;
- padding: 2px 4px;
-}
-.menu-item {
- padding: 4px;
-}
-.menu-separator {
- border-top: 1px solid #777;
- height: 0px;
-}
-.menu-item:hover {
- background: lightblue;
-}
-
-.check {
- display: inline-block;
- width: 1em;
-}
-.check.checked:before {
- content: '✓';
-}
-
-/* reference track */
-.pileup-root > .reference {
- flex: 0 0 20px; /* fixed height */
-}
-
-.background {
- fill: white;
-}
-.basepair.A { fill: #188712; }
-.basepair.G { fill: #C45C16; }
-.basepair.C { fill: #0600F9; }
-.basepair.T { fill: #F70016; }
-.basepair.U { fill: #F70016; }
-.basepair text, text.basepair {
- text-anchor: middle;
-}
-.loose text {
- font-size: 24;
-}
-.tight text {
- font-size: 12;
- font-weight: bold;
-}
-
-/* gene track */
-.pileup-root > .genes {
- flex: 0 0 50px;
-}
-.gene {
- stroke-width: 1;
- stroke: blue;
-}
-.gene text {
- font-size: 16px;
- text-anchor: middle;
- stroke: black;
- alignment-baseline: hanging;
-}
-#sense, #antisense .main {
- stroke: blue;
- fill: none;
- stroke-width: 1;
-}
-#antisense .offset, #sense .offset {
- stroke: white;
- fill: none;
- stroke-width: 1;
-}
-.exon {
- fill: blue;
- stroke: none;
-}
-
-/* pileup track */
-.pileup-root > .pileup {
- flex: 1; /* stretch to fill remaining space */
-}
-.pileup .alignment .match {
- fill: #c8c8c8; /* matches IGV */
-}
-.pileup text.basepair {
- alignment-baseline: hanging;
- font-size: 12;
- font-weight: bold;
-}
-.pileup .insert {
- stroke: rgb(97, 0, 216); /* matches IGV */
- stroke-width: 2;
-}
-.pileup .delete {
- stroke: black;
- stroke-width: 2;
-}
-.pileup .network-status {
- height: 100%;
- width: 100%;
- display: flex;
- align-items: center;
- justify-content: center;
-}
-.pileup .network-status-message {
- padding: 4px 8px;
- width: auto;
- background: #eee;
- border-radius: 3px;
- border: 1px solid #ccc;
- font-size: small;
-}
-
-.pileup .mate-connector {
- stroke: #c8c8c8; /* matches IGV */
-}
-
-/* variants */
-.pileup-root > .variants {
- flex: 0 0 25px; /* fixed height */
-}
-.variants rect {
- fill: #ddd;
- stroke: blue;
-}
-
-/* coverage track */
-.pileup-root > .coverage {
- flex: 0 0 50px; /* fixed height */
-}
-.coverage rect.bin {
- stroke-width: 0.1;
- stroke: white;
- fill: #a0a0a0;
-}
-.coverage .y-axis {
- stroke: black;
- stroke-width: 1;
-}
-.coverage .y-axis g.tick text {
- color: black;
- font-size: x-small;
- stroke: whitesmoke;
- stroke-width: 2;
- paint-order: stroke;
-}
-.coverage .y-axis path {
- stroke-width: 0;
-}
-.coverage rect.y-axis-background {
- fill: white;
- opacity: 0.5;
-}
-
-/* location track */
-.pileup-root > .location {
- flex: 0 0 20px; /* fixed height */
-}
-.location .location-hline, .location .location-vline-left, .location .location-vline-right {
- stroke: gray;
- stroke-width: 1.5;
-}
-.location .location-label {
- color: black;
- font-size: smaller;
- text-anchor: start;
- dominant-baseline: central;
-}
-
-/* scale track */
-.pileup-root > .scale {
- flex: 0 0 20px; /* fixed height */
-}
-.scale .scale-lline, .scale .scale-rline {
- stroke: gray;
- stroke-width: 1.5;
-}
-.scale .scale-label {
- color: black;
- font-weight: bold;
- font-size: smaller;
- dominant-baseline: central;
- text-anchor: middle;
-}
diff --git a/base/utils/gcloud.py b/base/utils/gcloud.py
index b44854a3..82dc4414 100644
--- a/base/utils/gcloud.py
+++ b/base/utils/gcloud.py
@@ -20,6 +20,9 @@ def store_item(kind, name, **kwargs):
def query_item(kind, filters=None, projection=()):
+ """
+ Filter items from google datastore using a query
+ """
# filters:
# [("var_name", "=", 1)]
ds = google_datastore()
@@ -32,7 +35,7 @@ def query_item(kind, filters=None, projection=()):
def get_item(kind, name):
"""
- returns item by kind and name
+ returns item by kind and name from google datastore
"""
ds = google_datastore()
result = ds.get(ds.key(kind, name))
diff --git a/base/utils/genetic_utils.py b/base/utils/genetic_utils.py
index 16e0912c..ea6b2225 100644
--- a/base/utils/genetic_utils.py
+++ b/base/utils/genetic_utils.py
@@ -18,6 +18,10 @@
def arm_or_center(chrom, pos):
+ """
+ Determines whether a position is on the
+ arm or center of a chromosome.
+ """
if chrom == 'MtDNA':
return None
ca = CHROM_ARM_CENTER[chrom]
diff --git a/base/utils/google_sheets.py b/base/utils/google_sheets.py
index 68bc106f..55060ebc 100644
--- a/base/utils/google_sheets.py
+++ b/base/utils/google_sheets.py
@@ -33,8 +33,12 @@ def authenticate_google_sheets():
def get_google_sheet(google_sheet):
- # In order for this to work you must share the worksheet with the travis service-account.
- # cendr-travis-ci@andersen-lab.iam.gserviceaccount.com
- # Note that the GOOGLE_SHEET dict is used above and expects the key to match the worksheet.
+ """
+ In order for this to work you must share the worksheet with the travis service-account.
+ cendr-travis-ci@andersen-lab.iam.gserviceaccount.com
+
+ Note that the GOOGLE_SHEET dict is used above and expects the key to match the worksheet.
+ """
gsheet = authenticate_google_sheets()
- return gsheet.open_by_key(GOOGLE_SHEETS[google_sheet]).worksheet(google_sheet)
\ No newline at end of file
+ google_sheets_key = GOOGLE_SHEETS[google_sheet]
+ return gsheet.open_by_key(google_sheets_key).worksheet(google_sheet)
diff --git a/base/utils/template_filters.py b/base/utils/template_filters.py
index 05e74aa6..f8d948eb 100644
--- a/base/utils/template_filters.py
+++ b/base/utils/template_filters.py
@@ -5,6 +5,7 @@
# Custom Filters
#
+
@app.template_filter('comma')
def comma_filter(value):
return "{:,.0f}".format(value)
diff --git a/base/utils/text_utils.py b/base/utils/text_utils.py
index 6dc699b9..0c76110e 100644
--- a/base/utils/text_utils.py
+++ b/base/utils/text_utils.py
@@ -13,4 +13,4 @@
def render_markdown(filename, directory="base/static/content/markdown"):
with open(os.path.join(directory, filename)) as f:
- return Markup(markdown.markdown(f.read()))
\ No newline at end of file
+ return Markup(markdown.markdown(f.read()))
diff --git a/base/views/api/api_docs.py b/base/views/api/api_docs.py
index fcd9f39d..2f77de4c 100644
--- a/base/views/api/api_docs.py
+++ b/base/views/api/api_docs.py
@@ -1,7 +1,4 @@
-from base.models import strain
-from base.models2 import strain_m
from base.application import app
-from base.utils.decorators import jsonify_request
from flask import send_from_directory
@@ -9,4 +6,4 @@
@app.route("/data/api/docs/")
def docs(path="index.html"):
print(path)
- return send_from_directory('../docs/build/', path)
+ return send_from_directory('../cendr-api-docs/docs/', path)
diff --git a/base/views/api/variant.py b/base/views/api/variant.py
index f5b0c188..2232d623 100644
--- a/base/views/api/variant.py
+++ b/base/views/api/variant.py
@@ -72,11 +72,11 @@ def variant_api():
'variant_impact': query['variant_impact'].split("_"),
'sample_tracks': query['sample_tracks'].split("_"),
'output': query['output'],
- 'list-all-strains': query['list-all-strains']
+ 'list-all-strains': query['list-all-strains'] == 'true'
}
app.logger.info(query)
samples = query['sample_tracks']
- if query['list-all-strains'] == 'true':
+ if query['list-all-strains']:
samples = "ALL"
elif not samples[0]:
samples = "N2"
diff --git a/base/views/data.py b/base/views/data.py
index 8186dc39..6183e780 100644
--- a/base/views/data.py
+++ b/base/views/data.py
@@ -19,7 +19,7 @@
# Data Page
#
-@data_bp.route('/')
+@data_bp.route('/release/latest')
@data_bp.route('/release/')
@data_bp.route('/release/')
@cache.memoize(50)
@@ -28,7 +28,7 @@ def data(selected_release=CURRENT_RELEASE):
Default data page - lists
available releases.
"""
- title = "Data"
+ title = "Releases"
strain_listing = query_strains(release=selected_release)
# Fetch variant data
url = "https://storage.googleapis.com/elegansvariation.org/releases/{selected_release}/multiqc_bcftools_stats.json".format(selected_release=selected_release)
diff --git a/cendr-api-docs b/cendr-api-docs
index f184772b..fa46fdc4 160000
--- a/cendr-api-docs
+++ b/cendr-api-docs
@@ -1 +1 @@
-Subproject commit f184772b04ee86d196fc130dd91b8d1f658bb566
+Subproject commit fa46fdc43d6e7a91b9c3f645efccc4614b5e6a53